Literature DB >> 34014408

Reducing the risk of bleeding after myomectomy: is preemptive embolization a valuable tool?

Ylann Abrahami1, Sophia Najid1, Arthur Petit2, Eric Sauvanet3, Luigi Novelli2.   

Abstract

PURPOSE: Abdominal myomectomy can be a challenging procedure, with elevated intraoperative blood loss and post-operative complications such as the need for blood transfusion and hemostasis with sometimes hysterectomy. Previous studies suggested that preemptive uterine artery embolization (PUAE) might reduce intraoperative blood loss.
MATERIALS AND METHODS: We reviewed all cases of abdominal myomectomy in our institution between January 2016 and June 2018. Out of 119 cases, 16 patients had PUAE and 103 did not. The objective of our study was to determine whereas PUAE reduced blood loss and post-operative complication rate.
RESULTS: In our study, there was no difference between the two groups in regard to average blood loss (128 vs 192 mL, OR 1,00 [0.99;1,01], p = 0,73), difference between pre- and post-operative hemoglobin level (- 1,15 g/dL vs - 1,32 g/dL, OR 0,91 [0.47;1,73], p = 0,79), and post-operative complications (need for transfusion, surgical revision, post-operative embolization, hysterectomy).
CONCLUSION: Our findings could not conclude that PUAE is effective in reducing intraoperative blood loss during abdominal myomectomy, but it should still be considered an option for patients with large or multiple myomas, with a specific situation or previously operated, who wish to preserve their uterus.

Entities:  

Keywords:  Gelatin sponge-like particles; Myomectomy; Preemptive; Uterine artery embolization; Uterine fibroids

Year:  2021        PMID: 34014408     DOI: 10.1186/s42155-021-00231-9

Source DB:  PubMed          Journal:  CVIR Endovasc        ISSN: 2520-8934


  16 in total

1.  Giant uterine leiomyoma devascularized by embolization prior to surgical removal.

Authors:  J Djelmis; D Mayer; M Majerovic; B Radanovic; V Starcevic
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  2001-12-01       Impact factor: 2.435

2.  Treatment of intrauterine and large pedunculated subserosal leiomyomata with sequential uterine artery embolization and myomectomy.

Authors:  Ben E Paxton; Judy M Lee; Hyun S Kim
Journal:  J Vasc Interv Radiol       Date:  2006-12       Impact factor: 3.464

Review 3.  Endovascular therapeutic embolisation: an overview of occluding agents and their effects on embolised tissues.

Authors:  Romaric Loffroy; Boris Guiu; Jean-Pierre Cercueil; Denis Krausé
Journal:  Curr Vasc Pharmacol       Date:  2009-04       Impact factor: 2.719

4.  [Preoperative embolization of uterine fibroma. Preliminary results (10 cases)].

Authors:  J H Ravina; J J Merland; D Herbreteau; E Houdart; J M Bouret; P Madelenat
Journal:  Presse Med       Date:  1994-10-29       Impact factor: 1.228

5.  Long-term outcome of uterine artery embolization for symptomatic uterine leiomyomas.

Authors:  Paul N M Lohle; Marianne J Voogt; Jolanda De Vries; Albert J Smeets; Harry A M Vervest; Leo E H Lampmann; Peter F Boekkooi
Journal:  J Vasc Interv Radiol       Date:  2008-03       Impact factor: 3.464

6.  Uterine artery embolization for treatment of leiomyomata: long-term outcomes from the FIBROID Registry.

Authors:  Scott C Goodwin; James B Spies; Robert Worthington-Kirsch; Eric Peterson; Gaylene Pron; Shuang Li; Evan R Myers
Journal:  Obstet Gynecol       Date:  2008-01       Impact factor: 7.661

7.  Morbidity associated with abdominal myomectomy.

Authors:  A I LaMorte; S Lalwani; M P Diamond
Journal:  Obstet Gynecol       Date:  1993-12       Impact factor: 7.661

8.  Interest of uterine artery embolization with gelatin sponge particles prior to myomectomy for large and/or multiple fibroids.

Authors:  Noémie Butori; Hervé Tixier; Laurence Filipuzzi; William Mutamba; Boris Guiu; Jean-Pierre Cercueil; Serge Douvier; Paul Sagot; Denis Krausé; Romaric Loffroy
Journal:  Eur J Radiol       Date:  2009-10-28       Impact factor: 3.528

9.  Preoperative uterine artery embolization (PUAE) before uterine fibroid myomectomy.

Authors:  E Dumousset; P Chabrot; B Rabischong; N Mazet; S Nasser; C Darcha; J M Garcier; G Mage; L Boyer
Journal:  Cardiovasc Intervent Radiol       Date:  2008 May-Jun       Impact factor: 2.740

10.  Myomectomy by laparoscopy: a preliminary report of 43 cases.

Authors:  J B Dubuisson; F Lecuru; H Foulot; L Mandelbrot; F X Aubriot; M Mouly
Journal:  Fertil Steril       Date:  1991-11       Impact factor: 7.329

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