Literature DB >> 34006910

A deep learning model for detection of cervical spinal cord compression in MRI scans.

Zamir Merali1, Justin Z Wang1, Jetan H Badhiwala1, Christopher D Witiw1,2, Jefferson R Wilson1,2, Michael G Fehlings3,4.   

Abstract

Magnetic Resonance Imaging (MRI) evidence of spinal cord compression plays a central role in the diagnosis of degenerative cervical myelopathy (DCM). There is growing recognition that deep learning models may assist in addressing the increasing volume of medical imaging data and provide initial interpretation of images gathered in a primary-care setting. We aimed to develop and validate a deep learning model for detection of cervical spinal cord compression in MRI scans. Patients undergoing surgery for DCM as a part of the AO Spine CSM-NA or CSM-I prospective cohort studies were included in our study. Patients were divided into a training/validation or holdout dataset. Images were labelled by two specialist physicians. We trained a deep convolutional neural network using images from the training/validation dataset and assessed model performance on the holdout dataset. The training/validation cohort included 201 patients with 6588 images and the holdout dataset included 88 patients with 2991 images. On the holdout dataset the deep learning model achieved an overall AUC of 0.94, sensitivity of 0.88, specificity of 0.89, and f1-score of 0.82. This model could improve the efficiency and objectivity of the interpretation of cervical spine MRI scans.

Entities:  

Year:  2021        PMID: 34006910     DOI: 10.1038/s41598-021-89848-3

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


  20 in total

Review 1.  Degenerative Cervical Myelopathy: Epidemiology, Genetics, and Pathogenesis.

Authors:  Aria Nouri; Lindsay Tetreault; Anoushka Singh; Spyridon K Karadimas; Michael G Fehlings
Journal:  Spine (Phila Pa 1976)       Date:  2015-06-15       Impact factor: 3.468

Review 2.  An overview of deep learning in medical imaging focusing on MRI.

Authors:  Alexander Selvikvåg Lundervold; Arvid Lundervold
Journal:  Z Med Phys       Date:  2018-12-13       Impact factor: 4.820

Review 3.  Imaging Evaluation of Degenerative Cervical Myelopathy: Current State of the Art and Future Directions.

Authors:  Allan R Martin; Nobuaki Tadokoro; Lindsay Tetreault; Elsa V Arocho-Quinones; Matthew D Budde; Shekar N Kurpad; Michael G Fehlings
Journal:  Neurosurg Clin N Am       Date:  2018-01       Impact factor: 2.509

4.  Pulmonary Nodule Detection in CT Images: False Positive Reduction Using Multi-View Convolutional Networks.

Authors:  Arnaud Arindra Adiyoso Setio; Francesco Ciompi; Geert Litjens; Paul Gerke; Colin Jacobs; Sarah J van Riel; Mathilde Marie Winkler Wille; Matiullah Naqibullah; Clara I Sanchez; Bram van Ginneken
Journal:  IEEE Trans Med Imaging       Date:  2016-03-01       Impact factor: 10.048

Review 5.  Machine learning and radiology.

Authors:  Shijun Wang; Ronald M Summers
Journal:  Med Image Anal       Date:  2012-02-23       Impact factor: 8.545

6.  Cervical myelopathy: a clinical and radiographic evaluation and correlation to cervical spondylotic myelopathy.

Authors:  James S Harrop; Swetha Naroji; Mitchell Maltenfort; D Greg Anderson; Todd Albert; John K Ratliff; Ravi K Ponnappan; Jeffery A Rihn; Harvey E Smith; Alan Hilibrand; Ashwini D Sharan; Alexander Vaccaro
Journal:  Spine (Phila Pa 1976)       Date:  2010-03-15       Impact factor: 3.468

7.  The modified Japanese Orthopaedic Association scale: establishing criteria for mild, moderate and severe impairment in patients with degenerative cervical myelopathy.

Authors:  Lindsay Tetreault; Branko Kopjar; Aria Nouri; Paul Arnold; Giuseppe Barbagallo; Ronald Bartels; Zhou Qiang; Anoushka Singh; Mehmet Zileli; Alexander Vaccaro; Michael G Fehlings
Journal:  Eur Spine J       Date:  2016-06-24       Impact factor: 3.134

Review 8.  Pathophysiology and natural history of cervical spondylotic myelopathy.

Authors:  Spyridon K Karadimas; W Mark Erwin; Claire G Ely; Joseph R Dettori; Michael G Fehlings
Journal:  Spine (Phila Pa 1976)       Date:  2013-10-15       Impact factor: 3.468

9.  Atlas-based segmentation of degenerated lumbar intervertebral discs from MR images of the spine.

Authors:  Sofia K Michopoulou; Lena Costaridou; Elias Panagiotopoulos; Robert Speller; George Panayiotakis; Andrew Todd-Pokropek
Journal:  IEEE Trans Biomed Eng       Date:  2009-04-14       Impact factor: 4.538

10.  Deep Learning in Medical Imaging.

Authors:  Mingyu Kim; Jihye Yun; Yongwon Cho; Keewon Shin; Ryoungwoo Jang; Hyun-Jin Bae; Namkug Kim
Journal:  Neurospine       Date:  2019-12-31
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  6 in total

1.  Brain Structural and Functional Dissociated Patterns in Degenerative Cervical Myelopathy: A Case-Controlled Retrospective Resting-State fMRI Study.

Authors:  Yi Zhou; Jiaqi Shi
Journal:  Front Neurol       Date:  2022-06-15       Impact factor: 4.086

2.  Automatic detection and voxel-wise mapping of lumbar spine Modic changes with deep learning.

Authors:  Kenneth T Gao; Radhika Tibrewala; Madeline Hess; Upasana U Bharadwaj; Gaurav Inamdar; Thomas M Link; Cynthia T Chin; Valentina Pedoia; Sharmila Majumdar
Journal:  JOR Spine       Date:  2022-06-08

3.  Deep Learning Model for Classifying Metastatic Epidural Spinal Cord Compression on MRI.

Authors:  James Thomas Patrick Decourcy Hallinan; Lei Zhu; Wenqiao Zhang; Desmond Shi Wei Lim; Sangeetha Baskar; Xi Zhen Low; Kuan Yuen Yeong; Ee Chin Teo; Nesaretnam Barr Kumarakulasinghe; Qai Ven Yap; Yiong Huak Chan; Shuxun Lin; Jiong Hao Tan; Naresh Kumar; Balamurugan A Vellayappan; Beng Chin Ooi; Swee Tian Quek; Andrew Makmur
Journal:  Front Oncol       Date:  2022-05-04       Impact factor: 5.738

4.  Deep Learning Model for Grading Metastatic Epidural Spinal Cord Compression on Staging CT.

Authors:  James Thomas Patrick Decourcy Hallinan; Lei Zhu; Wenqiao Zhang; Tricia Kuah; Desmond Shi Wei Lim; Xi Zhen Low; Amanda J L Cheng; Sterling Ellis Eide; Han Yang Ong; Faimee Erwan Muhamat Nor; Ahmed Mohamed Alsooreti; Mona I AlMuhaish; Kuan Yuen Yeong; Ee Chin Teo; Nesaretnam Barr Kumarakulasinghe; Qai Ven Yap; Yiong Huak Chan; Shuxun Lin; Jiong Hao Tan; Naresh Kumar; Balamurugan A Vellayappan; Beng Chin Ooi; Swee Tian Quek; Andrew Makmur
Journal:  Cancers (Basel)       Date:  2022-06-30       Impact factor: 6.575

5.  Study on Automatic Multi-Classification of Spine Based on Deep Learning and Postoperative Infection Screening.

Authors:  Hua Wang; Yanxiao Liu; Yancheng Li
Journal:  J Healthc Eng       Date:  2022-03-22       Impact factor: 2.682

6.  Evaluation of Deep Learning-Based Automated Detection of Primary Spine Tumors on MRI Using the Turing Test.

Authors:  Hanqiang Ouyang; Fanyu Meng; Jianfang Liu; Xinhang Song; Yuan Li; Yuan Yuan; Chunjie Wang; Ning Lang; Shuai Tian; Meiyi Yao; Xiaoguang Liu; Huishu Yuan; Shuqiang Jiang; Liang Jiang
Journal:  Front Oncol       Date:  2022-03-11       Impact factor: 6.244

  6 in total

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