Literature DB >> 34003333

Natural Products of the Fungal Genus Humicola: Diversity, Biological Activity, and Industrial Importance.

Sabrin R M Ibrahim1,2, Shaimaa G A Mohamed3, Ahmed E Altyar4, Gamal A Mohamed5,6.   

Abstract

Fungal metabolites are worthily taken into account as a pool of synthetically interesting and remarkably important new lead compounds for medical, agricultural, and chemical industries. Humicola species are known to have biotechnological and industrial potentials. Humicola genus (family Chaetomiaceae) is a prosperous fountainhead of unique and structurally diverse metabolites that have various bioactivities. Moreover, Humicola species attract substantial attention for their marked ability to produce thermostable enzymes with biotechnological and industrial importance. This review highlights the published researches on the isolated metabolites from the genus Humicola and their biological activities as well as the industrial importance of Humicola species. In the current review, more than 50 compounds are described and 84 references are cited.

Year:  2021        PMID: 34003333     DOI: 10.1007/s00284-021-02533-6

Source DB:  PubMed          Journal:  Curr Microbiol        ISSN: 0343-8651            Impact factor:   2.188


  50 in total

Review 1.  Fungal secondary metabolism: regulation, function and drug discovery.

Authors:  Nancy P Keller
Journal:  Nat Rev Microbiol       Date:  2019-03       Impact factor: 60.633

2.  Genetic transformation of germinated conidia of the thermophilic fungus Humicola grisea var. thermoidea to hygromycin B resistance.

Authors:  C Dantas-Barbosa; E F Araújo; L M Moraes; M H Vainstein; M O Azevedo
Journal:  FEMS Microbiol Lett       Date:  1998-12-01       Impact factor: 2.742

3.  Redefining Humicola sensu stricto and related genera in the Chaetomiaceae.

Authors:  X W Wang; F Y Yang; M Meijer; B Kraak; B D Sun; Y L Jiang; Y M Wu; F Y Bai; K A Seifert; P W Crous; R A Samson; J Houbraken
Journal:  Stud Mycol       Date:  2018-08-07       Impact factor: 16.097

4.  An alkaline thermostable recombinant Humicola grisea var. thermoidea cellobiohydrolase presents bifunctional (endo/exoglucanase) activity on cellulosic substrates.

Authors:  G S Oliveira; C J Ulhoa; M H L Silveira; J Andreaus; I Silva-Pereira; M J Poças-Fonseca; F P Faria
Journal:  World J Microbiol Biotechnol       Date:  2012-10-05       Impact factor: 3.312

5.  Characterization of a recombinant xylose tolerant β-xylosidase from Humicola grisea var. thermoidea and its use in sugarcane bagasse hydrolysis.

Authors:  Lorena Cardoso Cintra; Amanda Gregorim Fernandes; Izadora Cristina Moreira de Oliveira; Saulo J Linhares Siqueira; Ilítia Ganaê Oliveira Costa; Francieli Colussi; Rosália Santos Amorim Jesuíno; Cirano José Ulhoa; Fabrícia Paula de Faria
Journal:  Int J Biol Macromol       Date:  2017-07-08       Impact factor: 6.953

6.  Carbon source and pH-dependent transcriptional regulation of cellulase genes of Humicola grisea var. thermoidea grown on sugarcane bagasse.

Authors:  Thiago Machado Mello-de-Sousa; Ildinete Silva-Pereira; Marcio José Poças-Fonseca
Journal:  Enzyme Microb Technol       Date:  2010-09-21       Impact factor: 3.493

7.  Production pectin oligosaccharides using Humicola insolens Y1-derived unusual pectate lyase.

Authors:  Zhiyun Wang; Bo Xu; Huiying Luo; Kun Meng; Yuan Wang; Mengting Liu; Yingguo Bai; Bin Yao; Tao Tu
Journal:  J Biosci Bioeng       Date:  2019-08-08       Impact factor: 2.894

8.  Bioactive natural products from a sclerotium-colonizing isolate of Humicola fuscoatra.

Authors:  Biren K Joshi; James B Gloer; Donald T Wicklow
Journal:  J Nat Prod       Date:  2002-11       Impact factor: 4.050

9.  The importance of fungi and mycology for addressing major global challenges*.

Authors:  Lene Lange
Journal:  IMA Fungus       Date:  2014-12-12       Impact factor: 3.515

10.  The importance of fungi and of mycology for a global development of the bioeconomy.

Authors:  Lene Lange; Lasse Bech; Peter K Busk; Morten N Grell; Yuhong Huang; Mette Lange; Tore Linde; Bo Pilgaard; Doris Roth; Xiaoxue Tong
Journal:  IMA Fungus       Date:  2012-06-22       Impact factor: 3.515

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  6 in total

Review 1.  Untapped Potential of Marine-Associated Cladosporium Species: An Overview on Secondary Metabolites, Biotechnological Relevance, and Biological Activities.

Authors:  Gamal A Mohamed; Sabrin R M Ibrahim
Journal:  Mar Drugs       Date:  2021-11-18       Impact factor: 5.118

2.  Exploring the Activity of Fungal Phenalenone Derivatives as Potential CK2 Inhibitors Using Computational Methods.

Authors:  Sabrin R M Ibrahim; Alaa A Bagalagel; Reem M Diri; Ahmad O Noor; Hussain T Bakhsh; Yosra A Muhammad; Gamal A Mohamed; Abdelsattar M Omar
Journal:  J Fungi (Basel)       Date:  2022-04-24

Review 3.  Stachybotrys chartarum-A Hidden Treasure: Secondary Metabolites, Bioactivities, and Biotechnological Relevance.

Authors:  Sabrin R M Ibrahim; Hani Choudhry; Amer H Asseri; Mahmoud A Elfaky; Shaimaa G A Mohamed; Gamal A Mohamed
Journal:  J Fungi (Basel)       Date:  2022-05-12

Review 4.  Fungal Naphthalenones; Promising Metabolites for Drug Discovery: Structures, Biosynthesis, Sources, and Pharmacological Potential.

Authors:  Sabrin R M Ibrahim; Sana A Fadil; Haifa A Fadil; Bayan A Eshmawi; Shaimaa G A Mohamed; Gamal A Mohamed
Journal:  Toxins (Basel)       Date:  2022-02-19       Impact factor: 4.546

Review 5.  Chaetomugilins and Chaetoviridins-Promising Natural Metabolites: Structures, Separation, Characterization, Biosynthesis, Bioactivities, Molecular Docking, and Molecular Dynamics.

Authors:  Abdelsattar M Omar; Gamal A Mohamed; Sabrin R M Ibrahim
Journal:  J Fungi (Basel)       Date:  2022-01-27

Review 6.  Aspergillus ochraceus: Metabolites, Bioactivities, Biosynthesis, and Biotechnological Potential.

Authors:  Rawan H Hareeri; Mohammed M Aldurdunji; Hossam M Abdallah; Ali A Alqarni; Shaimaa G A Mohamed; Gamal A Mohamed; Sabrin R M Ibrahim
Journal:  Molecules       Date:  2022-10-10       Impact factor: 4.927

  6 in total

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