| Literature DB >> 33997600 |
Abstract
Though COVID vaccines have been available since December 2020, the rate at which they are administered remains slow, and in the meantime the pandemic continues to claim about as many lives every day as the 9/11 tragedy. I estimate that with the promised rate of vaccinations, if no additional non-pharmaceutical interventions are implemented, 203 thousand additional lives will be lost and the future cost of the pandemic will reach $1.3 trillion, or 6% of GDP. Using a cost-benefit analysis, I assess whether it is optimal for the United States to follow the lead of many European countries and introduce a nation-wide lockdown. I find that a lockdown would be indeed optimal and, depending on the assumptions, it should last between two and four weeks and will generate a net benefit of up to $653 billion.Entities:
Keywords: COVID-19; Cost-benefit analysis; Lockdown; Non-pharmaceutical interventions; Pandemic curve; Public health policy; Vaccinations
Year: 2021 PMID: 33997600 PMCID: PMC8105692 DOI: 10.1007/s41885-021-00083-6
Source DB: PubMed Journal: Econ Disaster Clim Chang ISSN: 2511-1299
Fig. 1Outcomes for an infected person. The figure presents possible outcomes for a person infected with the COVID-19 virus
Risks and Costs Associated with a COVID Infection
| Age Group | |||||||
|---|---|---|---|---|---|---|---|
| 0-19 | 20-44 | 45-54 | 55-64 | 65-74 | 75-84 | ≥ 85 | |
| % of US population | 25% | 33% | 13% | 13% | 9% | 5% | 2% |
| OUTCOME PROBABILITIES | |||||||
| Clinical outcomes | |||||||
| Prob. of hospitalization | 1.29% | 2.27% | 4.23% | 6.17% | 13.96% | 22.34% | 60.00% |
| Probability of dying (IFR) | 0.003% | 0.020% | 0.423% | 0.500% | 2.500% | 8.500% | 28.300% |
| Outcomes for symptomatic patients | |||||||
| Proportion high-risk | 8% | 15% | 24% | 33% | 51% | 51% | 51% |
| Outpatient visit | |||||||
| - low-risk patients | 32% | 32% | 32% | 31% | 62% | 62% | 62% |
| - high-risk patients | 77% | 63% | 63% | 63% | 82% | 82% | 82% |
| COST ESTIMATES | |||||||
| Case not medically attended | |||||||
| Medical cost (all risk) | $5 | $5 | $5 | $5 | $5 | $5 | $5 |
| Lost productivity (all risk) | $260 | $260 | $260 | $260 | $520 | $520 | $520 |
| Outpatient visit | |||||||
| Low-risk medical cost | $161 | $212 | $233 | $254 | $410 | $410 | $410 |
| Low-risk lost productivity | $520 | $520 | $780 | $1,040 | $1,560 | $1,560 | $1,560 |
| High-risk medical cost | $1,098 | $1,227 | $1,234 | $1,240 | $806 | $806 | $806 |
| High-risk lost productivity | $2,080 | $1,040 | $1,560 | $2,080 | $3,640 | $3,640 | $3,640 |
| Hospitalization | |||||||
| Low-risk medical cost | $25,408 | $32,174 | $34,960 | $37,745 | $19,379 | $19,379 | $19,379 |
| Low-risk lost productivity | $4,680 | $6,240 | $6,500 | $6,760 | $6,760 | $6,760 | $6,760 |
| High-risk medical cost | $70,938 | $80,760 | $75,334 | $69,908 | $28,346 | $28,346 | $28,346 |
| High-risk lost productivity | $11,960 | $10,920 | $11,700 | $12,480 | $9,360 | $9,360 | $9,360 |
| Fatalities | |||||||
| Low-risk lost productivity | $4,680 | $6,240 | $6,500 | $6,760 | $6,760 | $6,760 | $6,760 |
| High-risk lost productivity | $11,960 | $10,920 | $11,700 | $12,480 | $9,360 | $9,360 | $9,360 |
| Value of statistical life ($, mil.) | 5.76 | 12.34 | 10.05 | 7.75 | 5.29 | 5.29 | 5.29 |
SOURCES For hospitalization risks: (Reese et al. 2020) and CDC; for IFR: (Levin et al. 2020) and CDC’s “COVID-19 Pandemic Planning Scenarios,” Scenario 5; for high- and low-risk probabilities and cost estimates: (Molinari et al. 2007) and (CEA 2019); for productivity losses: (Molinari et al. 2007) and (Barrot et al. 2020); for VSL: (Aldy and Viscusi 2008) and (CEA 2019); author’s calculations
NOTES This table presents the risks and per-person medical risks and productivity costs associated with various outcomes of the COVID-19 infection
Fig. 2New symptomatic cases with no lockdown. SOURCES CDC COVID Data Tracker, Census Bureau, author’s calculations. SIR model inputs described in Table 5 of the Appendix. The figure plots the predicted number of new symptomatic cases produced by the SIR model. The model includes the effect of additional immunity acquired through vaccinations
Summary of variables, sources, and assumptions used in the paper
| Incremental cost of a lockdown ($36.93 billion per week). Source: average estimate from (OECD |
Fig. 3Savings from a lockdown as a function of its duration. SOURCES CDC COVID Data Tracker, Census Bureau, author’s calculations. SIR model inputs and other inputs used in the calculations are described in Table 5 of the Appendix. The figure plots projected savings from a lockdown as a function of the number of weeks it is kept in place, assuming that it is imposed a week from now
Fig. 4Incremental costs and savings of each additional week of a lockdown. SOURCES CDC COVID Data Tracker, Census Bureau, author’s calculations. Specific sources for SIR model inputs and incremental savings and cost estimates of a lockdown are provided in Table 5 of the Appendix. Assuming that a lockdown is imposed a week from now, this figure plots projected incremental costs and savings of extending lockdown by another week, to the number of weeks specified on the horizontal axis
Value of Discounted Quality-Adjusted Life Years, by Age
| Age Group | |||||||
|---|---|---|---|---|---|---|---|
| 0-19 | 20-44 | 45-54 | 55-64 | 65-74 | 75-84 | ≥ 85 | |
| Value of dQALY (($, mil.) | 4.05 | 3.44 | 2.73 | 2.22 | 1.71 | 1.14 | 0.82 |
SOURCES (Nyman et al. 2007) for QOL weights; National Vital Statistics Reports for life expectancy by age; author’s calculations
NOTES This table presents the dollar value of discounted quality-adjusted life years, calculated at the lower boundary of each age group. The discount rate is 3% per year, and the dollar value of QALY is $150,000
Sensitivity of the optimal lockdown duration to alternative assumptions
| Assumptions | ||||
|---|---|---|---|---|
| Optimal | Net savings relative to | |||
| Life is valued | Incremental cost | lockdown | no-lockdown baseline | |
| Lockdown | with | of lockdown | duration | ($, billion) |
| 0.620 | VSL | $36.93 bil. | 4 weeks | $653.13 |
| $46.16 bil. | 4 weeks | $616.20 | ||
| dQALY | $36.93 bil. | 2 weeks | $114.26 | |
| $46.16 bil. | 2 weeks | $95.79 | ||
| 0.775 | VSL | $36.93 bil. | 4 weeks | $578.29 |
| $46.16 bil. | 4 weeks | $541.36 | ||
| dQALY | $36.93 bil. | 2 weeks | $89.00 | |
| $46.16 bil. | 2 weeks | $70.53 | ||
SOURCES Author’s calculations
NOTES This table presents the optimal lockdown duration as a function of the assumptions listed in the table. The right-hand column presents the incremental net savings of a lockdown of optimal length calculated as its benefits minus the associated costs incurred over the lockdown duration
Sensitivity of the optimal lockdown duration to alternative assumptions, with IFR reduced by 25%
| Assumptions | ||||
|---|---|---|---|---|
| Optimal | Net savings relative to | |||
| Life is valued | Incremental cost | lockdown | no-lockdown baseline | |
| Lockdown | with | of lockdown | duration | ($, billion) |
| 0.620 | VSL | $36.93 bil. | 3 weeks | $464.51 |
| $46.16 bil. | 2 weeks | $409.20 | ||
| dQALY | $36.93 bil. | 2 weeks | $76.36 | |
| $46.16 bil. | 1 week | $44.53 | ||
| 0.775 | VSL | $36.93 bil. | 3 weeks | $401.64 |
| $46.16 bil. | 2 weeks | $341.88 | ||
| dQALY | $36.93 bil. | 2 weeks | $56.19 | |
| $46.16 bil. | 1 week | $31.24 | ||
SOURCES Author’s calculations
NOTES This table is an update of Table 3 in the main text based on the assumption that IFR for each age bin is reduced by 25%. It reports the optimal lockdown duration as a function of assumptions listed in the table. The right-hand column presents the incremental net savings of a lockdown of optimal length calculated as its benefits minus the associated costs incurred over the lockdown duration
Sensitivity of the optimal lockdown duration to alternative assumptions, assuming that only a one vaccine dose is administered during the vaccination program
| Assumptions | ||||
|---|---|---|---|---|
| Optimal | Net savings relative to | |||
| Life is valued | Incremental cost | lockdown | no-lockdown baseline | |
| Lockdown | with | of lockdown | duration | ($, billion) |
| 0.620 | VSL | $36.93 bil. | 4 weeks | $954.92 |
| $46.16 bil. | 4 weeks | $918.00 | ||
| dQALY | $36.93 bil. | 2 weeks | $162.98 | |
| $46.16 bil. | 2 weeks | $144.51 | ||
| 0.775 | VSL | $36.93 bil. | 4 weeks | $851.53 |
| $46.16 bil. | 4 weeks | $814.60 | ||
| dQALY | $36.93 bil. | 2 weeks | $131.24 | |
| $46.16 bil. | 2 weeks | $112.77 | ||
SOURCES Author’s calculations
NOTES This table reports the optimal lockdown duration as a function of assumptions listed in the table, assuming that the vaccination policy is to administer only one vaccine dose. The right-hand column presents the incremental net savings of a lockdown of optimal length calculated as its benefits minus the associated costs incurred over the lockdown duration
Optimal lockdown duration for the U.K. variant
| Assumptions | ||||
|---|---|---|---|---|
| Optimal | Net savings relative to | |||
| Life is valued | Incremental cost | lockdown | no-lockdown baseline | |
| Lockdown | with | of lockdown | duration | ($, billion) |
| 0.933 | VSL | $36.93 bil. | 8 weeks | $2,234.08 |
| $46.16 bil. | 8 weeks | $2,169.45 | ||
| dQALY | $36.93 bil. | 5 weeks | $477.71 | |
| $46.16 bil. | 5 weeks | $431.54 | ||
| 1.166 | VSL | $36.93 bil. | 8 weeks | $2,057.64 |
| $46.16 bil. | 8 weeks | $1,983.78 | ||
| dQALY | $36.93 bil. | 6 weeks | $411.61 | |
| $46.16 bil. | 5 weeks | $357.78 | ||
SOURCES Author’s calculations
NOTES This table presents the optimal lockdown duration as a function of the assumptions listed in the table, estimated for the U.K. variant of the SARS-CoV-2 virus. The right-hand column presents the incremental net savings of a lockdown of optimal length calculated as its benefits minus the associated costs incurred over the lockdown duration