Literature DB >> 33994549

Are Oral Mucosal Changes a Sign of COVID-19? A Cross-Sectional Study at a Field Hospital.

A Nuño González1, K Magaletskyy1, P Martín Carrillo2, B Lozano Masdemont3, A Mayor Ibarguren1, M Feito Rodríguez1, P Herranz Pinto1.   

Abstract

Background: Coronavirus disease 19 (COVID-19) has many manifestations, including respiratory, thrombotic, neurologic, digestive, and cutaneous ones. Cutaneous manifestations have been classified into 5 clinical patterns: acro-ischemic (pseudo-chilblain), vesicular, urticarial, maculopapular, and livedoid. Oral manifestations have also been reported, but much less frequently. Patients and methods: We performed a cross-sectional study in which we examined the oral mucosa of 666 patients with COVID-19 at the IFEMA field hospital in Madrid in April 2020.
Results: Seventy-eight patients (11.7%) had changes involving the oral mucosa. The most common were transient anterior U-shaped lingual papillitis (11.5%) accompanied or not by tongue swelling (6.6%), aphthous stomatitis (6.9%), a burning sensation in the mouth (5.3%), mucositis (3.9%), glossitis with patchy depapillation (3.9%), white tongue (1.6%), and enanthema (0.5%). Most of the patients also reported taste disturbances. Conclusions: COVID-19 also manifests in the oral cavity. The most common manifestations are transient U-shaped lingual papillitis, glossitis with patchy depapillation, and burning mouth syndrome. Mucositis with or without aphthous ulcers or enanthema may also be observed. Any these findings may be key clues to a diagnosis of COVID-19.
© 2021 Published by Elsevier España, S.L.U. on behalf of AEDV.

Keywords:  Anterior lingual papillitis; Aphthae; COVID-19; Coronavirus; Dysgeusia; Enanthema; Macroglossia; Mucositis; Oral changes; Oral manifestations; Papillitis; Swollen tongue

Year:  2021        PMID: 33994549      PMCID: PMC8113105          DOI: 10.1016/j.adengl.2021.05.010

Source DB:  PubMed          Journal:  Actas Dermosifiliogr (Engl Ed)        ISSN: 2173-5778


  10 in total

1.  Enanthem in Patients With COVID-19 and Skin Rash.

Authors:  Juan Jimenez-Cauhe; Daniel Ortega-Quijano; Dario de Perosanz-Lobo; Patricia Burgos-Blasco; Sergio Vañó-Galván; Montse Fernandez-Guarino; Diego Fernandez-Nieto
Journal:  JAMA Dermatol       Date:  2020-10-01       Impact factor: 10.282

Review 2.  Cutaneous Manifestations in the Context of SARS-CoV-2 Infection (COVID-19).

Authors:  J M Carrascosa; V Morillas; I Bielsa; M Munera-Campos
Journal:  Actas Dermosifiliogr       Date:  2020-10-15

3.  Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China.

Authors:  Ling Mao; Huijuan Jin; Mengdie Wang; Yu Hu; Shengcai Chen; Quanwei He; Jiang Chang; Candong Hong; Yifan Zhou; David Wang; Xiaoping Miao; Yanan Li; Bo Hu
Journal:  JAMA Neurol       Date:  2020-06-01       Impact factor: 18.302

4.  Cutaneous manifestations in COVID-19: a first perspective.

Authors:  S Recalcati
Journal:  J Eur Acad Dermatol Venereol       Date:  2020-05       Impact factor: 6.166

5.  Oral mucosal lesions in patients with SARS-CoV-2 infection. Report of four cases. Are they a true sign of COVID-19 disease?

Authors:  Roberto Onner Cruz Tapia; Alberto Jose Peraza Labrador; Douglas Magno Guimaraes; Luciano Hermios Matos Valdez
Journal:  Spec Care Dentist       Date:  2020-09-03

6.  Cutaneous manifestations related to coronavirus disease 2019 (COVID-19): A prospective study from China and Italy.

Authors:  Vincenzo De Giorgi; Sebastiano Recalcati; Ziyi Jia; Wei Chong; Renyu Ding; Yunhua Deng; Federica Scarfi; Federico Venturi; Luciana Trane; Alessia Gori; Flavia Silvestri; Xing-Hua Gao; Torello Lotti
Journal:  J Am Acad Dermatol       Date:  2020-05-19       Impact factor: 11.527

7.  Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study.

Authors:  Jerome R Lechien; Carlos M Chiesa-Estomba; Daniele R De Siati; Mihaela Horoi; Serge D Le Bon; Alexandra Rodriguez; Didier Dequanter; Serge Blecic; Fahd El Afia; Lea Distinguin; Younes Chekkoury-Idrissi; Stéphane Hans; Irene Lopez Delgado; Christian Calvo-Henriquez; Philippe Lavigne; Chiara Falanga; Maria Rosaria Barillari; Giovanni Cammaroto; Mohamad Khalife; Pierre Leich; Christel Souchay; Camelia Rossi; Fabrice Journe; Julien Hsieh; Myriam Edjlali; Robert Carlier; Laurence Ris; Andrea Lovato; Cosimo De Filippis; Frederique Coppee; Nicolas Fakhry; Tareck Ayad; Sven Saussez
Journal:  Eur Arch Otorhinolaryngol       Date:  2020-04-06       Impact factor: 2.503

8.  Oral lesions in patients with SARS-CoV-2 infection: could the oral cavity be a target organ?

Authors:  Thaís Bianca Brandão; Luiz Alcino Gueiros; Thayanara Silva Melo; Ana Carolina Prado-Ribeiro; Ana Cristina Froelich Alo Nesrallah; Gladys Villas Boas Prado; Alan Roger Santos-Silva; Cesar Augusto Migliorati
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol       Date:  2020-08-18

9.  Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases.

Authors:  C Galván Casas; A Català; G Carretero Hernández; P Rodríguez-Jiménez; D Fernández-Nieto; A Rodríguez-Villa Lario; I Navarro Fernández; R Ruiz-Villaverde; D Falkenhain-López; M Llamas Velasco; J García-Gavín; O Baniandrés; C González-Cruz; V Morillas-Lahuerta; X Cubiró; I Figueras Nart; G Selda-Enriquez; J Romaní; X Fustà-Novell; A Melian-Olivera; M Roncero Riesco; P Burgos-Blasco; J Sola Ortigosa; M Feito Rodriguez; I García-Doval
Journal:  Br J Dermatol       Date:  2020-06-10       Impact factor: 11.113

10.  Prevalence of mucocutaneous manifestations in 666 patients with COVID-19 in a field hospital in Spain: oral and palmoplantar findings.

Authors:  A Nuno-Gonzalez; P Martin-Carrillo; K Magaletsky; M D Martin Rios; C Herranz Mañas; J Artigas Almazan; G García Casasola; E Perez Castro; A Gallego Arenas; A Mayor Ibarguren; M Feito Rodríguez; B Lozano Masdemont; M Beato; E Ruiz Bravo; P Oliver; M D Montero Vega; P Herranz Pinto
Journal:  Br J Dermatol       Date:  2020-11-02       Impact factor: 11.113

  10 in total

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