Literature DB >> 3399182

A comparison of umbilical cord treatment in the control of superficial infection.

O Smales1.   

Abstract

Owing to a high incidence of superficial infection in the newborn period the existing cord care treatment of Iodosan 10% in surgical spirit was compared with 4% chlorhexidine detergent solution. A prospective crossover study was performed between two comparable maternity units. Cord bacteriology was assessed at the time of discharge from hospital and the day of cord separation recorded. The number of infections involving skin, eyes and umbilical cord occurring in hospital and at home were recorded. Chlorhexidine treatment of the cord was associated with an overall reduction in bacterial colonisation of the cord. This was most marked for coagulase positive staphylococci and was not associated with an increase in gram negative organisms. Cord separation occurred at a mean of 10 days with Iodosan and 20 days with chlorhexidine. Chlorhexidine treatment was associated with fewer infections overall; 21% of babies v 38% of babies treated with Iodosan. Conjunctival infection was most commonly recorded; 48 babies being affected in the Iodosan group and 20 in the chlorhexidine group. The use of 4% chlorhexidine detergent solution is supported, but the length of treatment may have to be limited in order to encourage cord separation.

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Year:  1988        PMID: 3399182

Source DB:  PubMed          Journal:  N Z Med J        ISSN: 0028-8446


  8 in total

Review 1.  Safety and impact of chlorhexidine antisepsis interventions for improving neonatal health in developing countries.

Authors:  Luke C Mullany; Gary L Darmstadt; James M Tielsch
Journal:  Pediatr Infect Dis J       Date:  2006-08       Impact factor: 2.129

2.  Care of the umbilical cord after birth: A limited review of recent literature.

Authors:  C R Walker
Journal:  Paediatr Child Health       Date:  1999-03       Impact factor: 2.253

Review 3.  Clinical, microbial, and biochemical aspects of the exfoliative toxins causing staphylococcal scalded-skin syndrome.

Authors:  S Ladhani; C L Joannou; D P Lochrie; R W Evans; S M Poston
Journal:  Clin Microbiol Rev       Date:  1999-04       Impact factor: 26.132

4.  Newborn umbilical cord and skin care in Sylhet District, Bangladesh: implications for the promotion of umbilical cord cleansing with topical chlorhexidine.

Authors:  M A Alam; N A Ali; N Sultana; L C Mullany; K C Teela; N U Z Khan; A H Baqui; S El Arifeen; I Mannan; G L Darmstadt; P J Winch
Journal:  J Perinatol       Date:  2008-12       Impact factor: 2.521

Review 5.  Topical umbilical cord care at birth.

Authors:  J Zupan; P Garner; A A A Omari
Journal:  Cochrane Database Syst Rev       Date:  2004

6.  Umbilical cord care: a pilot study comparing topical human milk, povidone-iodine, and dry care.

Authors:  Gulsen Vural; Sezer Kisa
Journal:  J Obstet Gynecol Neonatal Nurs       Date:  2006 Jan-Feb

Review 7.  Role of antimicrobial applications to the umbilical cord in neonates to prevent bacterial colonization and infection: a review of the evidence.

Authors:  Luke C Mullany; Gary L Darmstadt; James M Tielsch
Journal:  Pediatr Infect Dis J       Date:  2003-11       Impact factor: 2.129

Review 8.  Umbilical cord antiseptics for preventing sepsis and death among newborns.

Authors:  Aamer Imdad; Resti Ma M Bautista; Kathlynne Anne A Senen; Ma Esterlita V Uy; Jacinto Blas Mantaring; Zulfiqar A Bhutta
Journal:  Cochrane Database Syst Rev       Date:  2013-05-31
  8 in total

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