Literature DB >> 33989661

New Drugs on the Horizon for Functional and Motility Gastrointestinal Disorders.

Michael Camilleri1.   

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Year:  2021        PMID: 33989661      PMCID: PMC8380736          DOI: 10.1053/j.gastro.2021.04.079

Source DB:  PubMed          Journal:  Gastroenterology        ISSN: 0016-5085            Impact factor:   33.883


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  23 in total

1.  A G protein signaling-biased agonist at the μ-opioid receptor reverses morphine tolerance while preventing morphine withdrawal.

Authors:  Travis W Grim; Cullen L Schmid; Edward L Stahl; Fani Pantouli; Jo-Hao Ho; Agnes Acevedo-Canabal; Nicole M Kennedy; Michael D Cameron; Thomas D Bannister; Laura M Bohn
Journal:  Neuropsychopharmacology       Date:  2019-08-23       Impact factor: 7.853

2.  Current Practice in the Diagnosis of Bile Acid Diarrhea.

Authors:  Priya Vijayvargiya; Michael Camilleri
Journal:  Gastroenterology       Date:  2019-03-05       Impact factor: 22.682

Review 3.  Relamorelin for the treatment of gastrointestinal motility disorders.

Authors:  Victor Chedid; Michael Camilleri
Journal:  Expert Opin Investig Drugs       Date:  2017-08-31       Impact factor: 6.206

Review 4.  Emerging drugs for the treatment of non-alcoholic steatohepatitis: a focused review of farnesoid X receptor agonists.

Authors:  Raj A Shah; Naim Alkhouri; Kris V Kowdley
Journal:  Expert Opin Emerg Drugs       Date:  2020-08-12       Impact factor: 4.191

5.  Effects of NK1 receptors on gastric motor functions and satiation in healthy humans: results from a controlled trial with the NK1 antagonist aprepitant.

Authors:  Deepti Jacob; Irene Busciglio; Duane Burton; Houssam Halawi; Ibironke Oduyebo; Deborah Rhoten; Michael Ryks; W Scott Harmsen; Michael Camilleri
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2017-08-16       Impact factor: 4.052

6.  Randomised clinical trial: significant biochemical and colonic transit effects of the farnesoid X receptor agonist tropifexor in patients with primary bile acid diarrhoea.

Authors:  Michael Camilleri; Sara Linker Nord; Duane Burton; Ibironke Oduyebo; Yiming Zhang; Jin Chen; Koeun Im; Prafulla Bhad; Michael K Badman; David S Sanders; Julian R F Walters
Journal:  Aliment Pharmacol Ther       Date:  2020-07-23       Impact factor: 8.171

7.  The response of patients with bile acid diarrhoea to the farnesoid X receptor agonist obeticholic acid.

Authors:  J R F Walters; I M Johnston; J D Nolan; C Vassie; M E Pruzanski; D A Shapiro
Journal:  Aliment Pharmacol Ther       Date:  2014-10-20       Impact factor: 8.171

Review 8.  Biased versus Partial Agonism in the Search for Safer Opioid Analgesics.

Authors:  Joaquim Azevedo Neto; Anna Costanzini; Roberto De Giorgio; David G Lambert; Chiara Ruzza; Girolamo Calò
Journal:  Molecules       Date:  2020-08-25       Impact factor: 4.411

9.  Olorinab (APD371), a peripherally acting, highly selective, full agonist of the cannabinoid receptor 2, reduces colitis-induced acute and chronic visceral hypersensitivity in rodents.

Authors:  Joel Castro; Sonia Garcia-Caraballo; Jessica Maddern; Gudrun Schober; Amanda Lumsden; Andrea Harrington; Shirdi Schmiel; Beatriz Lindstrom; John Adams; Stuart M Brierley
Journal:  Pain       Date:  2022-01-01       Impact factor: 6.961

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  1 in total

Review 1.  Current Treatment Options and Therapeutic Insights for Gastrointestinal Dysmotility and Functional Gastrointestinal Disorders.

Authors:  Rajan Singh; Hannah Zogg; Uday C Ghoshal; Seungil Ro
Journal:  Front Pharmacol       Date:  2022-01-25       Impact factor: 5.810

  1 in total

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