Jing Zhao1,2,3, Wen Yang4, Jiao Zhao5, Yang Shen1,2,3, Ling Sun1,2,3, Tian Han1,2,3, Xiaoying Wang1,2,3, Peijun Yao1,2,3, Xingtao Zhou1,2,3. 1. Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China. 2. NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China. 3. Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China. 4. Department of Ophthalmology, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu, China. 5. Department of Ophthalmology, People's Hospital of Leshan, Leshan, China.
Abstract
BACKGROUND: To observe the changes in corneal densitometry (CD) with a Pentacam after implantable collamer lens (ICL) V4c implantation in myopia patients, and to investigate potential influencing factors. METHODS: We reviewed 65 eyes of 33 patients (mean age, 29.08±5.54 years) with myopia or myopic astigmatism who underwent ICL V4c implantation. Clinic parameters and Pentacam images of corneal topography and CD were obtained pre- and postoperatively. RESULTS: After an average of 52±2.2 months follow-up, the efficacy and safety indexes assessed at the last follow-up were 1.03±0.18 and 1.21±0.21, respectively. Except in the central annular zone of 0-2 mm, the CD values increased significantly at postoperative day 1 and decreased significantly until postoperative 1 year (P<0.05). The increase in CD values at different annular zones at postoperative day 1 was ranked as: 0-2 mm <2-6 mm < 6-10 mm. No significant difference was observed in corneal density at 1 week, 1 month, and 1-year follow-up when compared with the preoperative value (P>0.05). The CD value at 4 years follow-up increased significantly and correlated positively with age and preoperative uncorrected distance visual acuity, and negatively with preoperative spherical equivalent and intraocular pressure (IOP) (P<0.05). CONCLUSIONS: ICL V4c implantation demonstrated safety and efficacy for myopia correction. The CD value increased at 4 years postoperatively and correlated with age, preoperative spherical equivalent, uncorrected distance visual acuity, and IOP. 2021 Annals of Translational Medicine. All rights reserved.
BACKGROUND: To observe the changes in corneal densitometry (CD) with a Pentacam after implantable collamer lens (ICL) V4c implantation in myopia patients, and to investigate potential influencing factors. METHODS: We reviewed 65 eyes of 33 patients (mean age, 29.08±5.54 years) with myopia or myopic astigmatism who underwent ICL V4c implantation. Clinic parameters and Pentacam images of corneal topography and CD were obtained pre- and postoperatively. RESULTS: After an average of 52±2.2 months follow-up, the efficacy and safety indexes assessed at the last follow-up were 1.03±0.18 and 1.21±0.21, respectively. Except in the central annular zone of 0-2 mm, the CD values increased significantly at postoperative day 1 and decreased significantly until postoperative 1 year (P<0.05). The increase in CD values at different annular zones at postoperative day 1 was ranked as: 0-2 mm <2-6 mm < 6-10 mm. No significant difference was observed in corneal density at 1 week, 1 month, and 1-year follow-up when compared with the preoperative value (P>0.05). The CD value at 4 years follow-up increased significantly and correlated positively with age and preoperative uncorrected distance visual acuity, and negatively with preoperative spherical equivalent and intraocular pressure (IOP) (P<0.05). CONCLUSIONS: ICL V4c implantation demonstrated safety and efficacy for myopia correction. The CD value increased at 4 years postoperatively and correlated with age, preoperative spherical equivalent, uncorrected distance visual acuity, and IOP. 2021 Annals of Translational Medicine. All rights reserved.
Authors: Friederike Schaub; Philip Enders; Cornelius Bluhm; Björn O Bachmann; Claus Cursiefen; Ludwig M Heindl Journal: Am J Ophthalmol Date: 2016-12-14 Impact factor: 5.258
Authors: Nuria Garzón; Francisco Poyales; Igor Illarramendi; Javier Mendicute; Óscar Jáñez; Pedro Caro; Alfredo López; Francisco Argüeso Journal: Int Ophthalmol Date: 2016-11-11 Impact factor: 2.031