Literature DB >> 33986220

Prevalence of Cannabinoid Use in Patients With Hip and Knee Osteoarthritis.

David G Deckey1, Nina J Lara, Matthew T Gulbrandsen, Jeffrey D Hassebrock, Mark J Spangehl, Joshua S Bingham.   

Abstract

INTRODUCTION: State legalization and widespread marketing efforts have increased the accessibility and consumption of off-label, non-FDA-approved, cannabinoid (CBD) products. Although clinical evidence is largely absent for the treatment of musculoskeletal pain, patients are experimenting with these products in efforts to relieve joint pain. Assessment of the prevalence, perceived efficacy compared with other nonsurgical modalities, and usage patterns is warranted. The purpose of this study was to report the prevalence and perceived self-efficacy of CBD products in patients with symptomatic hip and/or knee osteoarthritis (OA).
METHODS: Two-hundred consecutive patients presenting with painful hip or knee OA were surveyed at their initial evaluation at a large academic center. Using Single Assessment Numeric Evaluation (SANE) scores, survey questions assessed perceived pain and effectiveness of CBD products, in addition to other nonsurgical treatment modalities. Chart review provided demographic factors. Descriptive statistics were used to characterize the data.
RESULTS: Of the 200 patients (80 hip OA, 108 knee OA, and 12 both), 66% were female, and average age was 67 years (range 36 to 89 years). Twenty-four percent (48/200) of patients endorsed use of CBD products before their presentation. The average presenting SANE score (range 0 to 100) for non-CBD users was 50.8 compared with 41.3 among CBD users (P = 0.012). Sixty percent of patients learned about CBD through friends, and 67% purchased CBD directly from a dispensary. Oral tinctures (43%) and topical applications (36%) were the most commonly used forms. In addition, 8% of participants in this study had tried marijuana for their pain.
CONCLUSION: A 24% incidence of CBD usage was found among patients presenting with hip or knee OA. No significant perceived benefit of CBD use seems to exist compared with its nonuse, as patients who used CBD reported significantly worse SANE and visual analogue scale scores than nonusers at baseline. Follow-up studies are warranted to assess these findings.
Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Orthopaedic Surgeons.

Entities:  

Year:  2021        PMID: 33986220      PMCID: PMC7861619          DOI: 10.5435/JAAOSGlobal-D-20-00172

Source DB:  PubMed          Journal:  J Am Acad Orthop Surg Glob Res Rev        ISSN: 2474-7661


  21 in total

1.  Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis.

Authors:  D C Hammell; L P Zhang; F Ma; S M Abshire; S L McIlwrath; A L Stinchcomb; K N Westlund
Journal:  Eur J Pain       Date:  2015-10-30       Impact factor: 3.931

2.  Marijuana use by middle-aged and older adults in the United States, 2015-2016.

Authors:  Benjamin H Han; Joseph J Palamar
Journal:  Drug Alcohol Depend       Date:  2018-09-06       Impact factor: 4.492

3.  Should Cannabinoids Be Added to Multimodal Pain Regimens After Total Hip and Knee Arthroplasty?

Authors:  Thomas R Hickernell; Akshay Lakra; Ari Berg; Herbert J Cooper; Jeffrey A Geller; Roshan P Shah
Journal:  J Arthroplasty       Date:  2018-08-03       Impact factor: 4.757

4.  A One-Question Patient-Reported Outcome Measure Is Comparable to Multiple-Question Measures in Total Knee Arthroplasty Patients.

Authors:  Daniel C Austin; Michael T Torchia; Paul M Werth; Adriana P Lucas; Wayne E Moschetti; David S Jevsevar
Journal:  J Arthroplasty       Date:  2019-07-24       Impact factor: 4.757

Review 5.  Cannabinoids for the treatment of pain: an update on recent clinical trials.

Authors:  Mark Ware; Pierre Beaulieu
Journal:  Pain Res Manag       Date:  2005       Impact factor: 3.037

Review 6.  Therapeutic potential of cannabinoid-based drugs.

Authors:  Thomas W Klein; Catherine A Newton
Journal:  Adv Exp Med Biol       Date:  2007       Impact factor: 2.622

7.  Use of Tetrahydrocannabinol and Cannabidiol Products in the Perioperative Period Around Primary Unilateral Total Hip and Knee Arthroplasty.

Authors:  Robert P Runner; Andrew N Luu; Nader A Nassif; Travis S Scudday; Jay J Patel; Steven L Barnett; Robert S Gorab
Journal:  J Arthroplasty       Date:  2020-02-05       Impact factor: 4.757

8.  Correlation between Single Assessment Numerical Evaluation score and Lysholm score in primary total knee arthroplasty patients.

Authors:  Ted Sueyoshi; Gen Emoto; Toru Yato
Journal:  Arthroplast Today       Date:  2017-10-21

9.  Comparison of IKDC and SANE Outcome Measures Following Knee Injury in Active Female Patients.

Authors:  Andrew P Winterstein; Timothy A McGuine; Kathleen E Carr; Scott J Hetzel
Journal:  Sports Health       Date:  2013-11       Impact factor: 3.843

10.  Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs.

Authors:  Lauri-Jo Gamble; Jordyn M Boesch; Christopher W Frye; Wayne S Schwark; Sabine Mann; Lisa Wolfe; Holly Brown; Erin S Berthelsen; Joseph J Wakshlag
Journal:  Front Vet Sci       Date:  2018-07-23
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  4 in total

1.  UKA with a handheld robotic device results in greater surgeon physiological stress than conventional instrumentation.

Authors:  Amer Haffar; Chad A Krueger; Graham S Goh; Jess H Lonner
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2022-02-21       Impact factor: 4.342

2.  Prevalence of Cannabinoid (CBD) Use in Orthopaedic Sports Medicine Patients.

Authors:  David G Deckey; Matthew Doan; Jeffrey D Hassebrock; Karan A Patel; Kostas Economopoulos; John M Tokish; Joshua S Bingham; Anikar Chhabra
Journal:  Orthop J Sports Med       Date:  2022-04-05

3.  Self-Reported Cannabis Use Is Associated With a Lower Rate of Persistent Opioid Use After Total Joint Arthroplasty.

Authors:  Vishal Hegde; Daniel N Bracey; Roseann M Johnson; Yasmin Yazdani Farsad; Douglas A Dennis; Jason M Jennings
Journal:  Arthroplast Today       Date:  2022-09-19

4.  Cannabidiol as a treatment for arthritis and joint pain: an exploratory cross-sectional study.

Authors:  Nicholas Frane; Erik Stapleton; Cesar Iturriaga; Maximillian Ganz; Vijay Rasquinha; Robert Duarte
Journal:  J Cannabis Res       Date:  2022-08-24
  4 in total

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