Literature DB >> 32173619

Use of Tetrahydrocannabinol and Cannabidiol Products in the Perioperative Period Around Primary Unilateral Total Hip and Knee Arthroplasty.

Robert P Runner1, Andrew N Luu1, Nader A Nassif1, Travis S Scudday1, Jay J Patel1, Steven L Barnett1, Robert S Gorab1.   

Abstract

BACKGROUND: Given the opioid crisis in America, patients are trying alternative medications including tetrahydrocannabinol (THC) and other cannabidiol (CBD) containing products in the perioperative period, especially in states where these products are legal. This study sought to analyze usage rates of CBD/THC products in the perioperative period for primary unilateral total hip and knee arthroplasty (THA/TKA) patients and identify a possible association with post-operative opioid use.
METHODS: A prospective cohort of primary unilateral THA/TKA patients were enrolled at a single institution. Patients who completed detailed pain journals were retrospectively surveyed for CBD/THC product usage. Pain medications were converted to morphine milligram equivalents (MME).
RESULTS: Data from 195 of the 210 patients (92.9% response rate) following primary arthroplasty were analyzed. Overall, 16.4% of arthroplasty-22.6% (n = 19) of TKA and 11.7% (n = 13) of THA-patients used CBD/THC products in the perioperative period. There was a wide variety of usage patterns among those using CBD/THC products. In comparing CBD/THC users and non-users, there was no significant difference in the length of narcotic use, total morphine milligram equivalents taken, narcotic pills taken, average post-op pain scores, the percentage of patients requiring a refill of narcotics, or length of stay.
CONCLUSION: Understanding that CBD/THC usage was not consistent for patients who used these products, 22.6% of TKA and 11.7% of THA patients tried CBD/THC products in the perioperative period. In this small sample, CBD/THC use was not associated with a major effect on narcotic requirements. Further studies on the effects of CBD/THC are needed as these therapies become more widely available.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  arthroplasty; cannabidiol; cannabis; opioid epidemic; pain control after arthroplasty; tetrahydrocannabinol

Mesh:

Substances:

Year:  2020        PMID: 32173619     DOI: 10.1016/j.arth.2020.01.077

Source DB:  PubMed          Journal:  J Arthroplasty        ISSN: 0883-5403            Impact factor:   4.757


  10 in total

1.  Risk of Revision Surgery and Manipulation Under Anesthesia in Patients With Cannabis Use Disorder Undergoing Total Knee Arthroplasty.

Authors:  Senthil Sambandam; Varatharaj Mounasamy; Sudhakar Selvaraj; Dane Wukich
Journal:  Cureus       Date:  2022-01-07

2.  Preoperative cannabis use does not increase opioid utilization following primary total hip arthroplasty in a propensity matched analysis.

Authors:  Christian B Ong; Simarjeet Puri; Juliana Lebowitz; Yu-Fen Chiu; Alejandro Gonzalez Della Valle; Alexandra Sideris; Brian P Chalmers
Journal:  Arch Orthop Trauma Surg       Date:  2022-09-21       Impact factor: 2.928

Review 3.  Analyzing the Impact of Cannabinoids on the Treatment of Spinal Disorders.

Authors:  Rohan M Shah; Anjay Saklecha; Alpesh A Patel; Srikanth N Divi
Journal:  Curr Rev Musculoskelet Med       Date:  2022-02-08

4.  Impact of pre-operative recreational marijuana use on outcomes two years after orthopaedic surgery.

Authors:  Fernando D Albelo; Mitchell Baker; Tina Zhang; Matheus B Schneider; Julio J Jauregui; Vidushan Nadarajah; Sean J Meredith; Jonathan D Packer; R Frank Henn
Journal:  Int Orthop       Date:  2021-05-29       Impact factor: 3.075

Review 5.  Cannabidiol: A Brief Review of Its Therapeutic and Pharmacologic Efficacy in the Management of Joint Disease.

Authors:  Charles A Gusho; Tannor Court
Journal:  Cureus       Date:  2020-03-23

6.  Prevalence of Cannabinoid Use in Patients With Hip and Knee Osteoarthritis.

Authors:  David G Deckey; Nina J Lara; Matthew T Gulbrandsen; Jeffrey D Hassebrock; Mark J Spangehl; Joshua S Bingham
Journal:  J Am Acad Orthop Surg Glob Res Rev       Date:  2021-02-02

7.  Prevalence of Cannabinoid (CBD) Use in Orthopaedic Sports Medicine Patients.

Authors:  David G Deckey; Matthew Doan; Jeffrey D Hassebrock; Karan A Patel; Kostas Economopoulos; John M Tokish; Joshua S Bingham; Anikar Chhabra
Journal:  Orthop J Sports Med       Date:  2022-04-05

8.  Medical Cannabis Use Reduces Opioid Prescriptions in Patients With Osteoarthritis.

Authors:  Bryan Renslo; Ari Greis; Conan S Liu; Anjithaa Radakrishnan; Asif M Ilyas
Journal:  Cureus       Date:  2022-01-24

9.  Self-Reported Cannabis Use Is Associated With a Lower Rate of Persistent Opioid Use After Total Joint Arthroplasty.

Authors:  Vishal Hegde; Daniel N Bracey; Roseann M Johnson; Yasmin Yazdani Farsad; Douglas A Dennis; Jason M Jennings
Journal:  Arthroplast Today       Date:  2022-09-19

Review 10.  [Cannabis and cannabinoids for the treatment of acute and chronic pain].

Authors:  Michael Schäfer; Sascha Tafelski
Journal:  Anaesthesist       Date:  2021-07-01       Impact factor: 1.041

  10 in total

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