Literature DB >> 33972634

Psychosis risk individuals show poor fitness and discrepancies with objective and subjective measures.

David Kimhy1,2, Vijay A Mittal3,4,5,6,7, Katherine S F Damme8,9, Richard P Sloan10, Matthew N Bartels11,12, Alara Ozsan3,5, Luz H Ospina1.   

Abstract

Exercise is a promising intervention for individuals at clinical high-risk for psychosis (CHR). However, these youth may not be reliable reporters on fitness. There have been no investigations that utilized objective fitness assessment in this population. The present study objectively characterizes the level of fitness in CHR youth, compares the accuracy of self-report measures to objective fitness indices, and explores clinical factors that may influence the accuracy of self-reported measures of fitness. Forty CHR individuals completed an exercise survey and objective indices of fitness (i.e., VO2max and BMI). Forty healthy volunteers completed objective indices of fitness and a structured clinical interview ruling out the presence of psychiatric illness. CHR youth showed greater BMI and lowered VO2max compared to healthy volunteers. In the CHR group, self-report items (perceived fitness) did not reflect objective indices of fitness, whereas specific exercise behaviors (intensity of exercise) showed stronger correlations with objective fitness measurements. Exploratory analyses suggested that symptoms (grandiosity and avolition) related to errors in self-perception. Results indicate that CHR individuals are less fit than controls as indexed by objective measures of fitness and that it is important to consider unique population clinical characteristics when employing self-report data.

Entities:  

Year:  2021        PMID: 33972634     DOI: 10.1038/s41598-021-89301-5

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


  42 in total

1.  A Supervised Exercise Intervention for Youth at Risk for Psychosis: An Open-Label Pilot Study.

Authors:  Derek J Dean; Angela D Bryan; Raeana Newberry; Tina Gupta; Emily Carol; Vijay A Mittal
Journal:  J Clin Psychiatry       Date:  2017 Nov/Dec       Impact factor: 4.384

2.  Hippocampal Subregions Across the Psychosis Spectrum.

Authors:  Teresa Vargas; Derek J Dean; Kenneth Juston Osborne; Tina Gupta; Ivanka Ristanovic; Sekine Ozturk; Jessica Turner; Theo G M van Erp; Vijay Anand Mittal
Journal:  Schizophr Bull       Date:  2018-08-20       Impact factor: 9.306

3.  The impact of aerobic exercise training on cardiopulmonary functioning in individuals with schizophrenia.

Authors:  Hilary F Armstrong; Matthew N Bartels; Orest Paslavski; Darnell Cain; Hannah A Shoval; Jacob S Ballon; Samira Khan; Richard P Sloan; David Kimhy
Journal:  Schizophr Res       Date:  2016-03-11       Impact factor: 4.939

4.  Exercise practices in individuals at clinical high risk of developing psychosis.

Authors:  Stephanie Deighton; Jean Addington
Journal:  Early Interv Psychiatry       Date:  2013-11-20       Impact factor: 2.732

5.  Aerobic Exercise in People with Schizophrenia: Neural and Neurocognitive Benefits.

Authors:  Julia Vakhrusheva; Brielle Marino; T Scott Stroup; David Kimhy
Journal:  Curr Behav Neurosci Rep       Date:  2016-04-04

6.  The Impact of Aerobic Exercise on Brain-Derived Neurotrophic Factor and Neurocognition in Individuals With Schizophrenia: A Single-Blind, Randomized Clinical Trial.

Authors:  David Kimhy; Julia Vakhrusheva; Matthew N Bartels; Hilary F Armstrong; Jacob S Ballon; Samira Khan; Rachel W Chang; Marie C Hansen; Lindsey Ayanruoh; Amanda Lister; Eero Castrén; Edward E Smith; Richard P Sloan
Journal:  Schizophr Bull       Date:  2015-03-23       Impact factor: 9.306

7.  Effects of exercise therapy on cardiorespiratory fitness in patients with schizophrenia.

Authors:  Thomas W Scheewe; Tim Takken; René S Kahn; Wiepke Cahn; Frank J G Backx
Journal:  Med Sci Sports Exerc       Date:  2012-10       Impact factor: 5.411

8.  What prevents youth at clinical high risk for psychosis from engaging in physical activity? An examination of the barriers to physical activity.

Authors:  Raeana E Newberry; Derek J Dean; Madison D Sayyah; Vijay A Mittal
Journal:  Schizophr Res       Date:  2018-06-13       Impact factor: 4.939

9.  Physical activity level and medial temporal health in youth at ultra high-risk for psychosis.

Authors:  Vijay A Mittal; Tina Gupta; Joseph M Orr; Andrea Pelletier-Baldelli; Derek J Dean; Jessica R Lunsford-Avery; Ashley K Smith; Briana L Robustelli; Daniel R Leopold; Zachary B Millman
Journal:  J Abnorm Psychol       Date:  2013-11

10.  Aerobic fitness and body mass index in individuals with schizophrenia: Implications for neurocognition and daily functioning.

Authors:  David Kimhy; Julia Vakhrusheva; Matthew N Bartels; Hilary F Armstrong; Jacob S Ballon; Samira Khan; Rachel W Chang; Marie C Hansen; Lindsey Ayanruoh; Edward E Smith; Richard P Sloan
Journal:  Psychiatry Res       Date:  2014-09-03       Impact factor: 3.222

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  3 in total

1.  Low physical activity is associated with two hypokinetic motor abnormalities in psychosis.

Authors:  Sebastian Walther; Irena Vladimirova; Danai Alexaki; Lea Schäppi; Kathrine S F Damme; Vijay A Mittal; Stewart A Shankman; Katharina Stegmayer
Journal:  J Psychiatr Res       Date:  2021-11-08       Impact factor: 4.791

Review 2.  Hippocampal circuit dysfunction in psychosis.

Authors:  Samuel Knight; Robert McCutcheon; Daniella Dwir; Anthony A Grace; Owen O'Daly; Philip McGuire; Gemma Modinos
Journal:  Transl Psychiatry       Date:  2022-08-25       Impact factor: 7.989

3.  The efficacy and safety of exercise and physical activity on psychosis: A systematic review and meta-analysis.

Authors:  Christina Ziebart; Pavlos Bobos; Joy C MacDermid; Rochelle Furtado; Daniel J Sobczak; Michele Doering
Journal:  Front Psychiatry       Date:  2022-08-16       Impact factor: 5.435

  3 in total

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