Literature DB >> 33970324

First proof-of-concept evaluation of the FUSION-X-US-II prototype for the performance of automated breast ultrasound in healthy volunteers.

Benedikt Schaefgen1, Marija Juskic1, Madeleine Hertel2, Richard G Barr3, Marcus Radicke2, Anne Stieber4, André Hennigs1, Fabian Riedel1, Christof Sohn1, Joerg Heil1, Michael Golatta5.   

Abstract

PURPOSE: The FUSION-X-US-II prototype was developed to combine 3D-automated breast ultrasound (ABUS) and digital breast tomosynthesis in a single device without decompressing the breast. We evaluated the technical function, feasibility of the examination workflow, image quality, breast tissue coverage and patient comfort of the ABUS device of the new prototype.
METHODS: In this prospective feasibility study, the FUSION-X-US-II prototype was used to perform ABUS in 30 healthy volunteers without history of breast cancer. The ABUS images of the prototype were interpreted by a physician with specialization in breast diagnostics. Any detected lesions were measured and classified using BI-RADS® scores. Image quality was rated subjectively by the physician and coverage of the breast was measured. Patient comfort was evaluated by a questionnaire after the examination.
RESULTS: One hundred and six scans were performed (61 × CC, 23 × ML, 22 × MLO) in 60 breasts. Image acquisition and processing by the prototype was fast and accurate. Breast coverage by ABUS was approximately 90.8%. Sixteen breast lesions (all benign, classified as BIRADS® 2) were identified. The examination was tolerated by all patients.
CONCLUSION: The FUSION-X-US-II prototype allows a rapid ABUS scan with mostly high patient comfort. Technical developments resulted in an improvement of quality and coverage compared to previous prototype versions. The results are encouraging for a test of the prototype in a clinical setting in combination with tomosynthesis.
© 2021. The Author(s).

Entities:  

Keywords:  Automated breast ultrasound; Breast cancer; Diagnostics; Digital breast tomosynthesis; Multimodal imaging

Year:  2021        PMID: 33970324     DOI: 10.1007/s00404-021-06081-z

Source DB:  PubMed          Journal:  Arch Gynecol Obstet        ISSN: 0932-0067            Impact factor:   2.344


  17 in total

1.  Interobserver reliability of automated breast volume scanner (ABVS) interpretation and agreement of ABVS findings with hand held breast ultrasound (HHUS), mammography and pathology results.

Authors:  Michael Golatta; Dorothea Franz; Aba Harcos; Hans Junkermann; Geraldine Rauch; Alexander Scharf; Florian Schuetz; Christof Sohn; Joerg Heil
Journal:  Eur J Radiol       Date:  2013-03-27       Impact factor: 3.528

2.  Adding 3D automated breast ultrasound to mammography screening in women with heterogeneously and extremely dense breasts: Report from a hospital-based, high-volume, single-center breast cancer screening program.

Authors:  Brigitte Wilczek; Henryk E Wilczek; Lawrence Rasouliyan; Karin Leifland
Journal:  Eur J Radiol       Date:  2016-06-07       Impact factor: 3.528

3.  The performance of 3D ABUS versus HHUS in the visualisation and BI-RADS characterisation of breast lesions in a large cohort of 1,886 women.

Authors:  Athina Vourtsis; Aspasia Kachulis
Journal:  Eur Radiol       Date:  2017-08-21       Impact factor: 5.315

4.  Digital Mammography versus Digital Mammography Plus Tomosynthesis in Breast Cancer Screening: The Oslo Tomosynthesis Screening Trial.

Authors:  Per Skaane; Andriy I Bandos; Loren T Niklason; Sofie Sebuødegård; Bjørn H Østerås; Randi Gullien; David Gur; Solveig Hofvind
Journal:  Radiology       Date:  2019-02-19       Impact factor: 11.105

5.  One-view breast tomosynthesis versus two-view mammography in the Malmö Breast Tomosynthesis Screening Trial (MBTST): a prospective, population-based, diagnostic accuracy study.

Authors:  Sophia Zackrisson; Kristina Lång; Aldana Rosso; Kristin Johnson; Magnus Dustler; Daniel Förnvik; Hannie Förnvik; Hanna Sartor; Pontus Timberg; Anders Tingberg; Ingvar Andersson
Journal:  Lancet Oncol       Date:  2018-10-12       Impact factor: 41.316

6.  Assessing improvement in detection of breast cancer with three-dimensional automated breast US in women with dense breast tissue: the SomoInsight Study.

Authors:  Rachel F Brem; László Tabár; Stephen W Duffy; Marc F Inciardi; Jessica A Guingrich; Beverly E Hashimoto; Marla R Lander; Robert L Lapidus; Mary Kay Peterson; Jocelyn A Rapelyea; Susan Roux; Kathy J Schilling; Biren A Shah; Jessica Torrente; Ralph T Wynn; Dave P Miller
Journal:  Radiology       Date:  2014-10-17       Impact factor: 11.105

7.  Breast cancer screening with tomosynthesis (3D mammography) with acquired or synthetic 2D mammography compared with 2D mammography alone (STORM-2): a population-based prospective study.

Authors:  Daniela Bernardi; Petra Macaskill; Marco Pellegrini; Marvi Valentini; Carmine Fantò; Livio Ostillio; Paolina Tuttobene; Andrea Luparia; Nehmat Houssami
Journal:  Lancet Oncol       Date:  2016-06-23       Impact factor: 41.316

8.  Combined screening with ultrasound and mammography vs mammography alone in women at elevated risk of breast cancer.

Authors:  Wendie A Berg; Jeffrey D Blume; Jean B Cormack; Ellen B Mendelson; Daniel Lehrer; Marcela Böhm-Vélez; Etta D Pisano; Roberta A Jong; W Phil Evans; Marilyn J Morton; Mary C Mahoney; Linda Hovanessian Larsen; Richard G Barr; Dione M Farria; Helga S Marques; Karan Boparai
Journal:  JAMA       Date:  2008-05-14       Impact factor: 56.272

9.  Comparison of the performance of screening mammography, physical examination, and breast US and evaluation of factors that influence them: an analysis of 27,825 patient evaluations.

Authors:  Thomas M Kolb; Jacob Lichy; Jeffrey H Newhouse
Journal:  Radiology       Date:  2002-10       Impact factor: 11.105

10.  Sensitivity and specificity of mammography and adjunctive ultrasonography to screen for breast cancer in the Japan Strategic Anti-cancer Randomized Trial (J-START): a randomised controlled trial.

Authors:  Noriaki Ohuchi; Akihiko Suzuki; Tomotaka Sobue; Masaaki Kawai; Seiichiro Yamamoto; Ying-Fang Zheng; Yoko Narikawa Shiono; Hiroshi Saito; Shinichi Kuriyama; Eriko Tohno; Tokiko Endo; Akira Fukao; Ichiro Tsuji; Takuhiro Yamaguchi; Yasuo Ohashi; Mamoru Fukuda; Takanori Ishida
Journal:  Lancet       Date:  2015-11-05       Impact factor: 79.321

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