Cheng-Wei Huang1, Prashant P Desai2, Kenneth K Wei3, In-Lu Amy Liu4, Janet S Lee4, Huong Q Nguyen4. 1. Department of Hospital Medicine, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA, USA. 2. Department of Internal Medicine, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA, USA. 3. Department of Pulmonary and Critical Care Medicine, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA, USA. 4. Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA.
Abstract
BACKGROUND: Limited studies have explored post-discharge outcomes following Coronavirus Disease 2019 (COVID-19) hospitalisation. We sought to characterise patients discharged following a COVID-19 hospitalisation within a large integrated health system in the United States. METHODS: We performed a retrospective study of 2180 COVID-19 patients discharged between 1 April 2020 and 31 July 2020. The primary endpoint was all-cause observation stay or inpatient readmission within 30 days from discharge. Bivariate and multivariable logistic regression analyses were performed to estimate the association between key socio-demographic and clinical characteristics with risk of 30-day readmission. RESULTS: The 30-day readmission rate was 7.6% (n = 166); 30-day mortality rate was 1% (n = 19). Most readmissions were respiratory-related (58%) and occurred at a median time of 5 days post discharge. Adjusted models showed that prior hospitalisations (Odds Ratio = 2.36, [95% Confidence Interval: 1.59-3.50]), chronic pulmonary disease (1.57 [1.09-2.28]), and discharge to home health (1.46 [1.01-2.11]) were significantly associated with 30-day readmission. Longer duration from diagnosis to index admission was borderline associated with lower odds of readmission (0.95 [0.91-1.00]). CONCLUSION: Readmission and mortality rates for COVID-19 following discharge are low. Most readmissions occur early and are due to respiratory causes and may reflect the prolonged acute disease course.
BACKGROUND: Limited studies have explored post-discharge outcomes following Coronavirus Disease 2019 (COVID-19) hospitalisation. We sought to characterise patients discharged following a COVID-19 hospitalisation within a large integrated health system in the United States. METHODS: We performed a retrospective study of 2180 COVID-19 patients discharged between 1 April 2020 and 31 July 2020. The primary endpoint was all-cause observation stay or inpatient readmission within 30 days from discharge. Bivariate and multivariable logistic regression analyses were performed to estimate the association between key socio-demographic and clinical characteristics with risk of 30-day readmission. RESULTS: The 30-day readmission rate was 7.6% (n = 166); 30-day mortality rate was 1% (n = 19). Most readmissions were respiratory-related (58%) and occurred at a median time of 5 days post discharge. Adjusted models showed that prior hospitalisations (Odds Ratio = 2.36, [95% Confidence Interval: 1.59-3.50]), chronic pulmonary disease (1.57 [1.09-2.28]), and discharge to home health (1.46 [1.01-2.11]) were significantly associated with 30-day readmission. Longer duration from diagnosis to index admission was borderline associated with lower odds of readmission (0.95 [0.91-1.00]). CONCLUSION: Readmission and mortality rates for COVID-19 following discharge are low. Most readmissions occur early and are due to respiratory causes and may reflect the prolonged acute disease course.
Authors: Hugo Perazzo; Sandra W Cardoso; Maria Pia D Ribeiro; Rodrigo Moreira; Lara E Coelho; Emilia M Jalil; André Miguel Japiassú; Elias Pimentel Gouvêa; Estevão Portela Nunes; Hugo Boechat Andrade; Luciano Barros Gouvêa; Marcel Treptow Ferreira; Pedro Mendes de Azambuja Rodrigues; Ronaldo Moreira; Kim Geraldo; Lucilene Freitas; Vinicius V Pacheco; Esau Custódio João; Trevon Fuller; Verônica Diniz Rocha; Ceuci de Lima Xavier Nunes; Tâmara Newman Lobato Souza; Ana Luiza Castro Conde Toscano; Alexandre Vargas Schwarzbold; Helena Carolina Noal; Gustavo de Araujo Pinto; Paula Macedo de Oliveira Lemos; Carla Santos; Fernanda Carvalho de Queiroz Mello; Valdilea G Veloso; Beatriz Grinsztejn Journal: Lancet Reg Health Am Date: 2022-04-12
Authors: Cheng-Wei Huang; Albert S Yu; Hubert Song; Joon S Park; Stefanie S Wu; Vang Kou Khang; Christopher C Subject; Ernest Shen Journal: JAMA Netw Open Date: 2022-03-01
Authors: Cheng-Wei Huang; Joon S Park; Hubert Song; Vang Kou Khang; Albert S Yu; Huong Q Nguyen; Janet S Lee; Christopher C Subject; Ernest Shen Journal: J Gen Intern Med Date: 2022-09-14 Impact factor: 6.473