Literature DB >> 33969740

Concomitant Osteotomy Reduces Risk of Reoperation Following Cartilage Restoration Procedures of the Knee: A Matched Cohort Analysis.

Jacob G Calcei1, Kunal Varshneya2, Kyle R Sochacki3, Marc R Safran2, Geoffrey D Abrams2, Seth L Sherman2.   

Abstract

OBJECTIVE: The objective of this study is to compare the (1) reoperation rates, (2) 30-day complication rates, and (3) cost differences between patients undergoing isolated autologous chondrocyte implantation (ACI) or osteochondral allograft transplantation (OCA) procedures alone versus patients with concomitant osteotomy. STUDY
DESIGN: Retrospective cohort study, level III.
DESIGN: Patients who underwent knee ACI (Current Procedural Terminology [CPT] 27412) or OCA (CPT 27415) with minimum 2-year follow-up were queried from a national insurance database. Resulting cohorts of patients that underwent ACI and OCA were then divided into patients who underwent isolated cartilage restoration procedure and patients who underwent concomitant osteotomy (CPT 27457, 27450, 27418). Reoperation was defined by ipsilateral knee procedure after the index surgery. The 30-day postoperative complication rates were assessed using ICD-9-CM codes. The cost per patient was calculated.
RESULTS: A total of 1,113 patients (402 ACI, 67 ACI + osteotomy, 552 OCA, 92 OCA + osteotomy) were included (mean follow-up of 39.0 months). Reoperation rate was significantly higher after isolated ACI or OCA compared to ACI or OCA plus concomitant osteotomy (ACI 68.7% vs. ACI + osteotomy 23.9%; OCA 34.8% vs. OCA + osteotomy 16.3%). Overall complication rates were similar between isolated ACI (3.0%) and ACI + osteotomy (4.5%) groups and OCA (2.5%) and OCA + osteotomy (3.3%) groups. Payments were significantly higher in the osteotomy groups at day of surgery and 9 months compared to isolated ACI or OCA, but costs were similar by 2 years postoperatively.
CONCLUSIONS: Concomitant osteotomy at the time of index ACI or OCA procedure significantly reduces the risk of reoperation with a similar rate of complications and similar overall costs compared with isolated ACI or OCA.

Entities:  

Keywords:  autologous chondrocyte implantation; cartilage restoration; osteochondral allograft; osteotomy

Mesh:

Year:  2021        PMID: 33969740      PMCID: PMC8808908          DOI: 10.1177/19476035211011515

Source DB:  PubMed          Journal:  Cartilage        ISSN: 1947-6035            Impact factor:   3.117


  52 in total

1.  Osteochondral Allograft Transplantation and Opening Wedge Tibial Osteotomy: Clinical Results of a Combined Single Procedure.

Authors:  Albert C Hsu; Luis E P Tirico; Abraham G Lin; Pamela A Pulido; William D Bugbee
Journal:  Cartilage       Date:  2017-05-22       Impact factor: 4.634

Review 2.  Outcomes of osteochondral allograft transplantation in the knee.

Authors:  Jaskarndip Chahal; Allan E Gross; Christopher Gross; Nathan Mall; Tim Dwyer; Amanjot Chahal; Daniel B Whelan; Brian J Cole
Journal:  Arthroscopy       Date:  2013-03       Impact factor: 4.772

Review 3.  Autologous chondrocyte implantation: a systematic review.

Authors:  Joshua D Harris; Robert A Siston; Xueliang Pan; David C Flanigan
Journal:  J Bone Joint Surg Am       Date:  2010-09-15       Impact factor: 5.284

4.  Autologous chondrocyte implantation using the original periosteum-cover technique versus matrix-associated autologous chondrocyte implantation: a randomized clinical trial.

Authors:  Felix Zeifang; Doris Oberle; Corinna Nierhoff; Wiltrud Richter; Babak Moradi; Holger Schmitt
Journal:  Am J Sports Med       Date:  2009-12-04       Impact factor: 6.202

5.  Distal Femoral Fresh Osteochondral Allografts: Follow-up at a Mean of Twenty-two Years.

Authors:  Guy Raz; Oleg A Safir; David J Backstein; Paul T H Lee; Allan E Gross
Journal:  J Bone Joint Surg Am       Date:  2014-07-02       Impact factor: 5.284

6.  Do fresh osteochondral allografts successfully treat femoral condyle lesions?

Authors:  Yadin D Levy; Simon Görtz; Pamela A Pulido; Julie C McCauley; William D Bugbee
Journal:  Clin Orthop Relat Res       Date:  2013-01       Impact factor: 4.176

7.  High tibial osteotomy for unloading osteochondral defects in the medial compartment of the knee.

Authors:  Curtis Mina; William E Garrett; Ricardo Pietrobon; Richard Glisson; Laurence Higgins
Journal:  Am J Sports Med       Date:  2008-04-15       Impact factor: 6.202

8.  Articular cartilage lesions in 993 consecutive knee arthroscopies.

Authors:  Asbjørn Arøen; Sverre Løken; Stig Heir; Elling Alvik; Arne Ekeland; Odd G Granlund; Lars Engebretsen
Journal:  Am J Sports Med       Date:  2004 Jan-Feb       Impact factor: 6.202

9.  Long-term outcomes after first-generation autologous chondrocyte implantation for cartilage defects of the knee.

Authors:  Philipp Niemeyer; Stella Porichis; Matthias Steinwachs; Christoph Erggelet; Peter C Kreuz; Hagen Schmal; Markus Uhl; Nadir Ghanem; Norbert P Südkamp; Gian Salzmann
Journal:  Am J Sports Med       Date:  2013-10-21       Impact factor: 6.202

10.  Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation.

Authors:  M Brittberg; A Lindahl; A Nilsson; C Ohlsson; O Isaksson; L Peterson
Journal:  N Engl J Med       Date:  1994-10-06       Impact factor: 91.245

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