Literature DB >> 33969144

High-Capacity Cardiac Signal Acquisition System for Flexible, Simultaneous, Multidomain Acquisition.

Brian Zenger1,2,3,4, Jake A Bergquist1,2,4, Wilson W Good1,2,4, Bruce Steadman2, Rob S MacLeod1,2,3,4.   

Abstract

Capturing cardiac electrical propagation or electrocardiographic images demands simultaneous, multidomain recordings of electrocardiographic signals with adequate spatial and temporal resolution. Available systems can be cost-prohibitive or lack the necessary flexibility to capture signals from the heart and torso. We have designed and constructed a system that leverages affordable commercial products (Intantech, CA, USA) to create a complete, cardiac signal acquisition system that includes a flexible front end, analog signal conditioning, and defibrillation protection. The design specifications for this project were to (1) record up to 1024 channels simultaneously at a minimum of 1 kHz, (2) capture signals within the range of ± 30 mV with a resolution of 1 μV, and (3) provide a flexible interface for custom electrode inputs.We integrated the Intantech A/D conversion circuits to create a novel system, which meets all the required specifications. The system connects to a standard laptop computer under control of open-source software (Intantech). To test the system, we recorded electrograms from within the myocardium, on the heart surface, and on the body surface simultaneously from a porcine experimental preparation. Noise levels were comparable to both our existing, custom acquisition system and a commercial competitor. The cost per channel was $32 USD, totaling $33,800 USD for a complete system.

Entities:  

Year:  2021        PMID: 33969144      PMCID: PMC8106231          DOI: 10.22489/cinc.2020.188

Source DB:  PubMed          Journal:  Comput Cardiol (2010)        ISSN: 2325-887X


  8 in total

1.  Systems for measuring and tracking electrophysiologic distributions.

Authors:  P R Ershler; B W Steadman; K B Moore; R L Lux
Journal:  IEEE Eng Med Biol Mag       Date:  1998 Jan-Feb

2.  Sensitivity of epicardial electrical markers to acute ischemia detection.

Authors:  Kedar Aras; Brett Burton; Darrell Swenson; Rob MacLeod
Journal:  J Electrocardiol       Date:  2014-08-17       Impact factor: 1.438

3.  Spatial organization of acute myocardial ischemia.

Authors:  Kedar Aras; Brett Burton; Darrell Swenson; Rob MacLeod
Journal:  J Electrocardiol       Date:  2016-02-20       Impact factor: 1.438

4.  Amplifiers for bioelectric events: a design with a minimal number of parts.

Authors:  A C MettingVanRijn; A Peper; C A Grimbergen
Journal:  Med Biol Eng Comput       Date:  1994-05       Impact factor: 2.602

5.  Cardiac intramural electrical mapping reveals focal delays but no conduction velocity slowing in the peri-infarct region.

Authors:  Mark L Trew; Zoar J Engelman; Bryan J Caldwell; Nigel A Lever; Ian J LeGrice; Bruce H Smaill
Journal:  Am J Physiol Heart Circ Physiol       Date:  2019-08-16       Impact factor: 4.733

6.  Novel experimental model for studying the spatiotemporal electrical signature of acute myocardial ischemia: a translational platform.

Authors:  Brian Zenger; Wilson W Good; Jake A Bergquist; Brett M Burton; Jess D Tate; Leo Berkenbile; Vikas Sharma; Rob S MacLeod
Journal:  Physiol Meas       Date:  2020-02-05       Impact factor: 2.833

7.  Multiplexed, high density electrophysiology with nanofabricated neural probes.

Authors:  Jiangang Du; Timothy J Blanche; Reid R Harrison; Henry A Lester; Sotiris C Masmanidis
Journal:  PLoS One       Date:  2011-10-12       Impact factor: 3.240

8.  PFEIFER: Preprocessing Framework for Electrograms Intermittently Fiducialized from Experimental Recordings.

Authors:  Anton Rodenhauser; Wilson W Good; Brian Zenger; Jess Tate; Kedar Aras; Brett Burton; Rob S MacLeod
Journal:  J Open Source Softw       Date:  2018
  8 in total
  4 in total

1.  Body Surface Potential Mapping: Contemporary Applications and Future Perspectives.

Authors:  Jake Bergquist; Lindsay Rupp; Brian Zenger; James Brundage; Anna Busatto; Rob S MacLeod
Journal:  Hearts (Basel)       Date:  2021-11-05

2.  Transient recovery of epicardial and torso ST-segment ischemic signals during cardiac stress tests: A possible physiological mechanism.

Authors:  Brian Zenger; Wilson W Good; Jake A Bergquist; Lindsay C Rupp; Maura Perez; Gregory J Stoddard; Vikas Sharma; Rob S MacLeod
Journal:  J Electrocardiol       Date:  2021-07-21       Impact factor: 1.438

3.  Reconstruction of cardiac position using body surface potentials.

Authors:  Jake A Bergquist; Jaume Coll-Font; Brian Zenger; Lindsay C Rupp; Wilson W Good; Dana H Brooks; Rob S MacLeod
Journal:  Comput Biol Med       Date:  2022-01-20       Impact factor: 4.589

4.  Pharmacological and simulated exercise cardiac stress tests produce different ischemic signatures in high-resolution experimental mapping studies.

Authors:  Brian Zenger; Wilson W Good; Jake A Bergquist; Lindsay C Rupp; Maura Perez; Gregory J Stoddard; Vikas Sharma; Rob S MacLeod
Journal:  J Electrocardiol       Date:  2021-07-24       Impact factor: 1.380

  4 in total

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