Literature DB >> 33953562

Association Between Caregivers' Burden and Neuropsychiatric Symptoms in Female Patients with Alzheimer's Disease with Varying Dementia Severity.

Yu-An Chen1, Cheng-Chen Chang1,2, Wen-Fu Wang3,4, Ya-Sian Lin5, Kai-Ming Jhang3, Tzu-Ying Lo5, Hsin-Hung Wu5,6,7.   

Abstract

PURPOSE: This study examined the attributes causing higher burdens for caregivers caring for female patients with Alzheimer's disease by analyzing a combination of various variables, including demographic data, dementia severity, and neuropsychiatric symptoms. PATIENTS AND METHODS: This study included 99 female patients with Alzheimer's disease who were cared for by the dementia collaborative care team at Changhua Christian Hospital, Taiwan. Neuropsychiatric symptoms used in this study included affections (9 types), behavior symptoms (9 symptoms), and psychological symptoms (3 symptoms). The Apriori algorithm was employed to identify association rules that reveal the relationships among demographic data, dementia severity, neuropsychiatric symptoms, and caregivers' burden.
RESULTS: A total of 185 rules were determined, including 51 rules with little or no burden, 108 rules with mild to moderate burden, and 26 rules with moderate to severe burden. The major findings are as follows. Neuropsychiatric symptoms were associated with varying degrees of caregivers' burden among female patients aged 75 to 84 years with mild dementia. Crying spells and aggression were specifically associated with a moderate to severe burden. Delusion was associated with a mild to moderate and moderate to severe burden. Dysthymia and depression were associated with little or no burden to moderate to severe burden.
CONCLUSION: Clinicians can provide early interventions to reduce the burden of caregivers caring for female patients with Alzheimer's disease and can refer caregivers for timely assistance to reduce their burden.
© 2021 Chen et al.

Entities:  

Keywords:  Alzheimer’s disease; Apriori algorithm; caregiving burden; female patients; female patients with Alzheimer’s disease; neuropsychiatric symptom

Year:  2021        PMID: 33953562      PMCID: PMC8090980          DOI: 10.2147/JMDH.S298196

Source DB:  PubMed          Journal:  J Multidiscip Healthc        ISSN: 1178-2390


  30 in total

1.  The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.

Authors:  Marilyn S Albert; Steven T DeKosky; Dennis Dickson; Bruno Dubois; Howard H Feldman; Nick C Fox; Anthony Gamst; David M Holtzman; William J Jagust; Ronald C Petersen; Peter J Snyder; Maria C Carrillo; Bill Thies; Creighton H Phelps
Journal:  Alzheimers Dement       Date:  2011-04-21       Impact factor: 21.566

Review 2.  The relationship of specific items on the Neuropsychiatric Inventory to caregiver burden in dementia: a systematic review.

Authors:  Toril Marie Terum; John Roger Andersen; Arvid Rongve; Dag Aarsland; Ellen J Svendsboe; Ingelin Testad
Journal:  Int J Geriatr Psychiatry       Date:  2017-03-20       Impact factor: 3.485

Review 3.  Bidirectional relationship between caregiver burden and neuropsychiatric symptoms in patients with Alzheimer's disease: A narrative review.

Authors:  Ahmet Turan Isik; Pinar Soysal; Marco Solmi; Nicola Veronese
Journal:  Int J Geriatr Psychiatry       Date:  2018-09-10       Impact factor: 3.485

4.  Distress Associated with Dementia-Related Psychosis and Agitation in Relation to Healthcare Utilization and Costs.

Authors:  Donovan T Maust; Helen C Kales; Ryan J McCammon; Frederic C Blow; Amanda Leggett; Kenneth M Langa
Journal:  Am J Geriatr Psychiatry       Date:  2017-05-25       Impact factor: 4.105

5.  Behavioral and psychological symptoms of dementia characteristic of mild Alzheimer patients.

Authors:  Jin Shimabukuro; Shuichi Awata; Hiroo Matsuoka
Journal:  Psychiatry Clin Neurosci       Date:  2005-06       Impact factor: 5.188

6.  Alzheimer disease in the United States (2010-2050) estimated using the 2010 census.

Authors:  Liesi E Hebert; Jennifer Weuve; Paul A Scherr; Denis A Evans
Journal:  Neurology       Date:  2013-02-06       Impact factor: 9.910

7.  Association between patients with dementia and high caregiving burden for caregivers from a medical center in Taiwan.

Authors:  Guei-Jhen Yan; Wen-Fu Wang; Kai-Ming Jhang; Che-Wei Lin; Hsin-Hung Wu
Journal:  Psychol Res Behav Manag       Date:  2019-01-17

8.  Clinical and Demographic Predictors of Adverse Outcomes in Caregivers of Patients with Dementia.

Authors:  Sun Min Lee; Yunhwan Lee; Seong Hye Choi; Tae Sung Lim; So Young Moon
Journal:  Dement Neurocogn Disord       Date:  2019-04-24

9.  Neuropsychiatric symptoms as a predictor of caregiver burden in Alzheimer's disease.

Authors:  Ricardo F Allegri; Diego Sarasola; Cecilia M Serrano; Fernando E Taragano; Raúl L Arizaga; Judith Butman; Leandro Loñ
Journal:  Neuropsychiatr Dis Treat       Date:  2006-03       Impact factor: 2.570

10.  Care Needs of Community-Residing Male Patients with Vascular Cognitive Impairment.

Authors:  Kai-Ming Jhang; Wen-Fu Wang; Hao-Fang Chang; Yu-Huei Liu; Ming-Che Chang; Hsin-Hung Wu
Journal:  Neuropsychiatr Dis Treat       Date:  2020-11-03       Impact factor: 2.570

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  2 in total

1.  Using the Apriori Algorithm to Explore Caregivers' Depression by the Combination of the Patients with Dementia and Their Caregivers.

Authors:  Cheng-Chen Chang; Wen-Fu Wang; Yi-Ying Li; Yu-An Chen; Yen-Jen Chen; Yi-Cheng Liao; Kai-Ming Jhang; Hsin-Hung Wu
Journal:  Risk Manag Healthc Policy       Date:  2021-07-12

2.  Neuropsychiatric Symptoms of Alzheimer's Disease and Caregiver Burden.

Authors:  Behnam Iravani; Elaheh Abdollahi; Fatemeh Eslamdoust-Siahestalkhi; Robabeh Soleimani
Journal:  Front Neurol       Date:  2022-07-29       Impact factor: 4.086

  2 in total

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