Literature DB >> 33927496

Comparison of Preemptive Effect of Dexamethasone and Methylprednisolone After Third Molar Surgery: A Split-Mouth Randomized Triple-Blind Clinical Trial.

Nikhil Srivastava1, Akshay Shetty1, Praveen Kumar1, Diljith Rishi1, Vivek Bagga1, Saurabh G Kale1.   

Abstract

AIM: The study aimed to compare the efficacy of methylprednisolone and dexamethasone injected into masseter muscle preoperatively in surgical extraction of lower third molars.
MATERIALS AND METHODS: This study was carried out on 20 patients who reported to the department of Oral and Maxillofacial surgery, Sri Rajiv Gandhi College of Dental Sciences and Hospital Bangalore, requiring surgical removal of bilateral mandibular third molars. The efficacy of corticosteroid was evaluated based on its ability to reduce pain, swelling and trismus following the surgical extraction of impacted lower third molars.
RESULTS: There was no statistical difference between the two steroids with both of them achieving equal level of pain control. There was a statistically significant difference on the second postoperative day with dexamethasone showing clinically superior result. The difference in oral aperture was found to be statistically significant with dexamethasone showing a decreased reduction in postoperative mouth opening on both second and seventh day.
CONCLUSION: This study conclusively proves that patient comfort levels are far better with the use of dexamethasone. © The Association of Oral and Maxillofacial Surgeons of India 2020.

Entities:  

Keywords:  Dexamethasone; Intramassetric; Methylprednisolone; Randomized control trial; Third molar; Triple-blind study

Year:  2020        PMID: 33927496      PMCID: PMC8042070          DOI: 10.1007/s12663-020-01346-7

Source DB:  PubMed          Journal:  J Maxillofac Oral Surg        ISSN: 0972-8270


  19 in total

1.  Effect of submucosal and intramuscular dexamethasone on postoperative sequelae after third molar surgery: comparative study.

Authors:  Omer Waleed Majid; Waseem Khalid Mahmood
Journal:  Br J Oral Maxillofac Surg       Date:  2010-10-29       Impact factor: 1.651

2.  Efficacy of methylprednisolone injected into the masseter muscle following the surgical extraction of impacted lower third molars.

Authors:  E Vegas-Bustamante; J Micó-Llorens; J Gargallo-Albiol; M Satorres-Nieto; L Berini-Aytés; C Gay-Escoda
Journal:  Int J Oral Maxillofac Surg       Date:  2008-03-04       Impact factor: 2.789

3.  Effects of cortisone acetate and pituitary ACTH on rheumatoid arthritis, rheumatic fever and certain other conditions.

Authors:  P S HENCH; E C KENDALL; C H SLOCUMB; H F POLLEY
Journal:  Arch Intern Med (Chic)       Date:  1950-04

4.  Complications following removal of impacted third molars: the role of the experience of the surgeon.

Authors:  A L Sisk; W B Hammer; D W Shelton; E D Joy
Journal:  J Oral Maxillofac Surg       Date:  1986-11       Impact factor: 1.895

5.  Use of ibuprofen and methylprednisolone for the prevention of pain and swelling after removal of impacted third molars.

Authors:  S Schultze-Mosgau; R Schmelzeisen; J C Frölich; H Schmele
Journal:  J Oral Maxillofac Surg       Date:  1995-01       Impact factor: 1.895

6.  Is thermography useful for assessment of postoperative inflammation after surgical removal of mandibular third molars when methylprednisolone is administered and how does it correlate with patients' perception of swelling?

Authors:  Jennifer Christensen; Louise Hauge Matzen; Søren Schou; Michael Væth; Ann Wenzel
Journal:  J Oral Maxillofac Surg       Date:  2013-10-05       Impact factor: 1.895

7.  Effects of tube drain with primary closure technique on postoperative trismus and swelling after removal of fully impacted mandibular third molars.

Authors:  Ali Alp Sağlam
Journal:  Quintessence Int       Date:  2003-02       Impact factor: 1.677

8.  Effect of two routes of administration of dexamethasone on pain, edema, and trismus in impacted lower third molar surgery.

Authors:  Antonio Azoubel Antunes; Rafael Linard Avelar; Evandro Carneiro Martins Neto; Riedel Frota; Emanuel Dias
Journal:  Oral Maxillofac Surg       Date:  2011-08-16

9.  Pre-emptive effect of dexamethasone and methylprednisolone on pain, swelling, and trismus after third molar surgery: a split-mouth randomized triple-blind clinical trial.

Authors:  C E P Alcântara; S G M Falci; F Oliveira-Ferreira; C R R Santos; M L P Pinheiro
Journal:  Int J Oral Maxillofac Surg       Date:  2013-06-28       Impact factor: 2.789

10.  Clinical comparative study of the effectiveness of two dosages of Dexamethasone to control postoperative swelling, trismus and pain after the surgical extraction of mandibular impacted third molars.

Authors:  Jose Rodrigues Laureano Filho; Paul Edward Maurette; Marvis Allais; Milane Cotinho; Caio Fernandes
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2008-02-01
View more
  2 in total

Review 1.  Efficacy of Methylprednisolone Compared to Other Drugs for Pain, Swelling, and Trismus Control after Third Molar Surgery: A Meta-Analysis.

Authors:  Mariana González-Morelos; Lorenzo Franco-de la Torre; Diana Laura Franco-González; Eduardo Gómez-Sánchez; Ángel Josabad Alonso-Castro; Nelly Molina-Frechero; Luis Miguel Anaya-Esparza; Mario Alberto Isiordia-Espinoza
Journal:  Healthcare (Basel)       Date:  2022-06-01

2.  Can adjunctive corticosteroid therapy improve patient-centered outcomes following third molar surgery? A systematic review.

Authors:  P Parhizkar; P-R Schmidlin; M-M Bornstein; O Fakheran
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2022-09-01
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.