Literature DB >> 33910841

Associations Between Time to Treatment Start and Survival in Patients With Lung Cancer.

Trine Stokstad1,2, Sveinung Sørhaug3,4, Tore Amundsen3,4, Bjørn H Grønberg5,6.   

Abstract

BACKGROUND: Time-to-treatment is defined as a quality indicator for cancer care but is not well documented. We investigated whether meeting Norwegian timeframes of 35/42 days from referral until start of chemotherapy or surgery/radiotherapy for lung cancer was associated with survival. PATIENTS AND METHODS: The medical records of 439 lung cancer patients at a regional cancer center were reviewed and categorized according to treatment: (i) surgery; ii) radical radiotherapy; iii) stereotactic radiotherapy; iv) palliative treatment, no cancer symptoms; v) palliative treatment with severe cancer symptoms).
RESULTS: Proportions receiving timely treatment varied significantly at 39%, 48%, 10%, 44% and 89%, respectively (p<0.001). Overall, those starting treatment on time had the shortest median overall survival (10.6 vs. 22.6 months; p<0.001). This was also the case for palliative (5.3 vs. 11.4 months) (p<0.001) but not for curative treatment (not reached vs. 38.3 months) (p=0.038).
CONCLUSION: Timely treatment is not necessarily associated with improved survival. Copyright
© 2021, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  Quality of healthcare; cancer care; delayed treatment; quality indicator; treatment outcomes

Mesh:

Year:  2021        PMID: 33910841      PMCID: PMC8193294          DOI: 10.21873/invivo.12416

Source DB:  PubMed          Journal:  In Vivo        ISSN: 0258-851X            Impact factor:   2.406


  48 in total

1.  Rapid disease progression with delay in treatment of non-small-cell lung cancer.

Authors:  Nasiruddin Mohammed; Larry Llyn Kestin; Inga Siiner Grills; Madhu Battu; Dwight Lamar Fitch; Ching-Yee Oliver Wong; Jeffrey Harold Margolis; Gary William Chmielewski; Robert James Welsh
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-05-13       Impact factor: 7.038

2.  Timeliness of Treatment Initiation and Associated Survival Following Diagnosis of Non-Small-Cell Lung Cancer in South Carolina.

Authors:  Jarrod T Bullard; Jan M Eberth; Amanda K Arrington; Swann A Adams; Xi Cheng; Ramzi G Salloum
Journal:  South Med J       Date:  2017-02       Impact factor: 0.954

3.  Outcome in patients with lung cancer found on lung cancer mass screening roentgenograms, but who did not subsequently consult a doctor.

Authors:  Kosuke Kashiwabara; Syu-ichi Koshi; Kotaro Itonaga; Osamu Nakahara; Makoto Tanaka; Masakazu Toyonaga
Journal:  Lung Cancer       Date:  2003-04       Impact factor: 5.705

4.  Lung carcinoma symptoms--an independent predictor of survival and an important mediator of African-American disparity in survival.

Authors:  C Martin Tammemagi; Christine Neslund-Dudas; Michael Simoff; Paul Kvale
Journal:  Cancer       Date:  2004-10-01       Impact factor: 6.860

5.  Impact of comorbidity on lung cancer survival.

Authors:  C Martin Tammemagi; Christine Neslund-Dudas; Michael Simoff; Paul Kvale
Journal:  Int J Cancer       Date:  2003-03-01       Impact factor: 7.396

6.  Advanced non-small cell lung cancer in the elderly: the impact of age and comorbidities on treatment modalities and patient prognosis.

Authors:  Chia-Lin Hsu; Jen-Hau Chen; Kuan-Yu Chen; Jin-Yuan Shih; James Chih-Hsin Yang; Chong-Jen Yu; Pan-Chyr Yang
Journal:  J Geriatr Oncol       Date:  2014-09-22       Impact factor: 3.599

7.  Clinical and organizational factors in the initial evaluation of patients with lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.

Authors:  David E Ost; Sai-Ching Jim Yeung; Lynn T Tanoue; Michael K Gould
Journal:  Chest       Date:  2013-05       Impact factor: 9.410

8.  The role of receipt and timeliness of treatment in socioeconomic inequalities in lung cancer survival: population-based, data-linkage study.

Authors:  Lynne F Forrest; Jean Adams; Greg Rubin; Martin White
Journal:  Thorax       Date:  2014-06-12       Impact factor: 9.139

Review 9.  Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review.

Authors:  R D Neal; P Tharmanathan; B France; N U Din; S Cotton; J Fallon-Ferguson; W Hamilton; A Hendry; M Hendry; R Lewis; U Macleod; E D Mitchell; M Pickett; T Rai; K Shaw; N Stuart; M L Tørring; C Wilkinson; B Williams; N Williams; J Emery
Journal:  Br J Cancer       Date:  2015-03-31       Impact factor: 7.640

10.  Do diagnostic delays in cancer matter?

Authors:  R D Neal
Journal:  Br J Cancer       Date:  2009-12-03       Impact factor: 7.640

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  1 in total

1.  A long waiting time from diagnosis to treatment decreases the survival of non-small cell lung cancer patients with stage IA1: A retrospective study.

Authors:  Bin Liu; Jia-Yi Qian; Lei-Lei Wu; Jun-Quan Zeng; Shu-Quan Xu; Jin-Hua Yuan; Yong-Liang Zheng; Dong Xie; Xiaolu Chen; Hai-Hong Yu
Journal:  Front Surg       Date:  2022-09-07
  1 in total

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