| Literature DB >> 33907974 |
Hye Won Jeong1,2, Hyun-Ha Chang3, Eun Ji Kim4, Yu Kyung Kim5, Se-Mi Kim4, Eun-Ha Kim4, Young-Il Kim4, Mark Anthony B Casel4, Seong-Gyu Kim4, Rare Rollon4, Seung-Gyu Jang4, Kwang-Min Yu4, Hee-Sung Kim2, Hee Sue Park6, Su-Jin Park7, Yong-Dae Kim8,9, Eung-Gook Kim4, Young Ki Choi10.
Abstract
To compare the standardized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence of high epicenter region with non-epicenter region, serological studies were performed with a total of 3,268 sera from Daegu City and 3,981 sera from Chungbuk Province. Indirect immunofluorescence assay (IFA) for SARS-CoV-2 IgG results showed a high seroprevalence rate in the Daegu City (epicenter) compared with a non-epicenter area (Chungbuk Province) (1.27% vs. 0.91%, P = 0.0358). It is noteworthy that the highest seroprevalence in Daegu City was found in elderly patients (70's) whereas young adult patients (20's) in Chungbuk Province showed the highest seroprevalence. Neutralizing antibody (NAb) titers were found in three samples from Daegu City (3/3, 268, 0.09%) while none of the samples from Chungbuk Province were NAb positive. These results demonstrated that even following the large outbreak, the seropositive rate of SARS-CoV-2 in the general population remained low in South Korea.Entities:
Keywords: COVID-19; SARS-CoV-2; South Korea; epicenter; seroprevalence
Year: 2021 PMID： 33907974 PMCID： PMC8079228 DOI： 10.1007/s12275-021-1095-7
Source DB: PubMed Journal: J Microbiol ISSN： 1225-8873 Impact factor: 3.422