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35 in total

1. 4-nitrobenzyloxycarbonyl derivatives of O(6)-benzylguanine as hypoxia-activated prodrug inhibitors of O(6)-alkylguanine-DNA alkyltransferase (AGT), which produces resistance to agents targeting the O-6 position of DNA guanine.

Authors: Rui Zhu; Mao-Chin Liu; Mei-Zhen Luo; Philip G Penketh; Raymond P Baumann; Krishnamurthy Shyam; Alan C Sartorelli
Journal: J Med Chem Date: 2011-10-17 Impact factor: 7.446

2. Use of fenbendazole-containing therapeutic diets for mice in experimental cancer therapy studies.

Authors: Qiwen Duan; Yanfeng Liu; Carmen J Booth; Sara Rockwell
Journal: J Am Assoc Lab Anim Sci Date: 2012-03 Impact factor: 1.232

3. Quantification of Tumor Hypoxic Fractions Using Positron Emission Tomography with [¹⁸F]Fluoromisonidazole ([¹⁸F]FMISO) Kinetic Analysis and Invasive Oxygen Measurements.

Authors: Olivia J Kelada; Sara Rockwell; Ming-Qiang Zheng; Yiyun Huang; Yanfeng Liu; Carmen J Booth; Roy H Decker; Uwe Oelfke; Richard E Carson; David J Carlson
Journal: Mol Imaging Biol Date: 2017-12 Impact factor: 3.488

4. 1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[[1-(4-nitrophenyl)ethoxy]carbonyl]hydrazine: an anticancer agent targeting hypoxic cells.

Authors: Helen A Seow; Philip G Penketh; Krishnamurthy Shyam; Sara Rockwell; Alan C Sartorelli
Journal: Proc Natl Acad Sci U S A Date: 2005-06-17 Impact factor: 11.205

5. Influence of scheduling on two-drug combinations of alkylating agents in vivo.

Authors: B A Teicher; S A Holden; S M Jones; J P Eder; T S Herman
Journal: Cancer Chemother Pharmacol Date: 1989 Impact factor: 3.333

6. Reductive activation of the prodrug 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2-[[1-(4-nitrophenyl)ethoxy]carbonyl]hydrazine (KS119) selectively occurs in oxygen-deficient cells and overcomes O(6)-alkylguanine-DNA alkyltransferase mediated KS119 tumor cell resistance.

Authors: Raymond P Baumann; Philip G Penketh; Kimiko Ishiguro; Krishnamurthy Shyam; Yong L Zhu; Alan C Sartorelli
Journal: Biochem Pharmacol Date: 2009-12-11 Impact factor: 5.858

7. Generation of oxygen deficiency in cell culture using a two-enzyme system to evaluate agents targeting hypoxic tumor cells.

Authors: Raymond P Baumann; Philip G Penketh; Helen A Seow; Krishnamurthy Shyam; Alan C Sartorelli
Journal: Radiat Res Date: 2008-11 Impact factor: 2.841

In vivo-in vitro tumor systems: new models for studing the response of tumours to therapy.