Literature DB >> 33887482

A Leg to Stand on: Trauma Center Designation and Association with Rate of Limb Salvage in Patients Suffering Severe Lower Extremity Injury.

Corinne Bunn1, Sujay Kulshrestha2, Bianca Di Chiaro3, Uma Maduekwe4, Zaid M Abdelsattar5, Marshall S Baker6, Fred A Luchette6, Sonya Agnew7.   

Abstract

BACKGROUND: Mangled extremities are one of the most difficult injuries for trauma surgeons to manage. We compare limb salvage rates for a limb-threatening lower extremity injuries managed at Level I vs Level II trauma centers (TCs). STUDY
DESIGN: We identified all adult patients with a limb-threatening injury who underwent primary amputation or limb salvage (LS) using the American College of Surgeons (ACS) Trauma Quality Improvement Program database at ACS Level I vs II TCs between 2007 and 2017. A limb-threatening injury was defined as an open tibial fracture with concurrent arterial injury (Gustilo type IIIc). Multivariable analysis and propensity score matching were performed to minimize confounding by indication.
RESULTS: There were 712 records for analysis; 391 (54.9%) LS performed and 321 (45.1%) underwent amputation. The rate of LS was statistically higher among patients treated at Level I TCs vs those treated at Level II TCs (47.4% vs 34.8%; p = 0.01). Patients with penetrating injuries (13% vs 9.5%; p = 0.046) and tibial/peroneal artery injury (72.9% vs 50.4%; p < 0.001), as opposed to popliteal artery injury (30.8% vs 58.8%; p < 0.001), were more likely to have LS. The risk-adjusted odds of LS was 3.13 times higher at Level I TCs vs Level II TCs (95% CI, 1.59 to 6.34; p = 0.001). Limb salvage rates were significantly higher at Level I TCs compared with Level II TCs (53.0% vs 34.8%; p = 0.004), even after propensity matching.
CONCLUSIONS: In patients with a mangled extremity, limb salvage rates are 50% higher at Level I TCs compared with Level II TCs, independent of case mix and injury severity.
Copyright © 2021 American College of Surgeons. All rights reserved.

Entities:  

Mesh:

Year:  2021        PMID: 33887482      PMCID: PMC8238915          DOI: 10.1016/j.jamcollsurg.2021.04.012

Source DB:  PubMed          Journal:  J Am Coll Surg        ISSN: 1072-7515            Impact factor:   6.532


  39 in total

Review 1.  Limb reconstruction versus amputation decision making in massive lower extremity trauma.

Authors:  R H Lange
Journal:  Clin Orthop Relat Res       Date:  1989-06       Impact factor: 4.176

Review 2.  A meta-analysis of amputation versus limb salvage in mangled lower limb injuries--the patient perspective.

Authors:  Maheswara Akula; Sreenadh Gella; C J Shaw; Phil McShane; A M Mohsen
Journal:  Injury       Date:  2010-07-02       Impact factor: 2.586

3.  An analysis of outcomes of reconstruction or amputation after leg-threatening injuries.

Authors:  Michael J Bosse; Ellen J MacKenzie; James F Kellam; Andrew R Burgess; Lawrence X Webb; Marc F Swiontkowski; Roy W Sanders; Alan L Jones; Mark P McAndrew; Brendan M Patterson; Melissa L McCarthy; Thomas G Travison; Renan C Castillo
Journal:  N Engl J Med       Date:  2002-12-12       Impact factor: 91.245

4.  Trauma care regionalization: a process-outcome evaluation.

Authors:  J S Sampalis; R Denis; A Lavoie; P Fréchette; S Boukas; A Nikolis; D Benoit; D Fleiszer; R Brown; M Churchill-Smith; D Mulder
Journal:  J Trauma       Date:  1999-04

5.  Long-term results and costs of muscle flap coverage with Ilizarov bone transport in lower limb salvage.

Authors:  David W Lowenberg; Rudolf F Buntic; Gregory M Buncke; Brian M Parrett
Journal:  J Orthop Trauma       Date:  2013-10       Impact factor: 2.512

6.  TRISS methodology: an inappropriate tool for comparing outcomes between trauma centers.

Authors:  D Demetriades; L Chan; G V Velmanos; J Sava; C Preston; G Gruzinski; T V Berne
Journal:  J Am Coll Surg       Date:  2001-09       Impact factor: 6.113

7.  Factors influencing the decision to amputate or reconstruct after high-energy lower extremity trauma.

Authors:  Ellen J MacKenzie; Michael J Bosse; James F Kellam; Andrew R Burgess; Lawrence X Webb; Marc F Swiontkowski; Roy Sanders; Alan L Jones; Mark P McAndrew; Brendan Patterson; Melissa L McCarthy; Charles A Rohde
Journal:  J Trauma       Date:  2002-04

8.  Multiple imputation in trauma disparity research.

Authors:  Tolulope A Oyetunji; Joseph G Crompton; Imudia D Ehanire; Kent A Stevens; David T Efron; Elliott R Haut; David C Chang; Edward E Cornwell; Marie L Crandall; Adil H Haider
Journal:  J Surg Res       Date:  2010-10-16       Impact factor: 2.192

9.  Severe open fractures of the tibia.

Authors:  R J Caudle; P J Stern
Journal:  J Bone Joint Surg Am       Date:  1987-07       Impact factor: 5.284

10.  The mangled extremity and attempt for limb salvage.

Authors:  Anastasios V Korompilias; Alexandros E Beris; Marios G Lykissas; Marios D Vekris; Vasileios A Kontogeorgakos; Panayiotis N Soucacos
Journal:  J Orthop Surg Res       Date:  2009-02-13       Impact factor: 2.359

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