| Literature DB >> 33875265 |
David K Stevenson1, Nima Aghaeepour2, Ivana Maric3, Martin S Angst2, Gary L Darmstadt3, Maurice L Druzin4, Brice Gaudilliere2, Xuefeng B Ling5, Mira N Moufarrej6, Laura S Peterson3, Stephen R Quake6, David A Relman7, Michael P Snyder8, Karl G Sylvester9, Gary M Shaw3, Ronald J Wong3.
Abstract
To understand the disparities in spontaneous preterm birth (sPTB) and/or its outcomes, biologic and social determinants as well as healthcare practice (such as those in neonatal intensive care units) should be considered. Disparities in sPTB have been largely intractable and remain obscure in most cases, despite a myriad of identified risk factors for and causes of sPTB. We still do not know how they lead to the different outcomes at different gestational ages and if they are independent of NICU practices. Here we describe an integrated approach to study the interplay between the genome and exposome, which may drive biochemistry and physiology and lead to health disparities.Entities:
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Year: 2021 PMID： 33875265 PMCID： PMC9159791 DOI： 10.1016/j.semperi.2021.151408
Source DB: PubMed Journal: Semin Perinatol ISSN： 0146-0005 Impact factor: 3.311