| Literature DB >> 33868756 |
Sulhee Lee1,2, Young-Seo Park1.
Abstract
Water soluble propolis was prepared using β-cyclodextrin, and its effect on an ethanol-induced hangover was examined in Sprague-Dawley (SD) rats fed with ethanol. When SD rats were administrated with propolis 30 min after ethanol feeding, ethanol content in the rat serum decreased 2.1 times 1 h after ethanol feeding. Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) activity in rat liver increased 3.0 and 4.4 times, respectively, 1 h after ethanol feeding and administration of propolis 30 min after ethanol feeding. There were no differences in the expression of ADH and ALDH genes regardless of propolis administration. These results indicated that a decrease in ethanol content in the serum was not due to an increase in the expression of ADH or ALDH genes but rather, an increase in activities of ADH and ALDH. © The Korean Society of Food Science and Technology 2021.Entities:
Keywords: Alcohol dehydrogenase; Aldehyde dehydrogenase; Hangover-relieving drink; Propolis; Water soluble propolis
Year: 2021 PMID： 33868756 PMCID： PMC8017057 DOI： 10.1007/s10068-020-00869-6
Source DB: PubMed Journal: Food Sci Biotechnol ISSN： 1226-7708 Impact factor: 2.391