Literature DB >> 33868491

Three-phase Model of Visco-elastic Incompressible Fluid Flow and its Computational Implementation.

Shixin Xu1, Mark Alber1,2, Zhiliang Xu2.   

Abstract

Energetic Variational Approach is used to derive a novel thermodynamically consistent three-phase model of a mixture of Newtonian and visco-elastic fluids. The model which automatically satisfies the energy dissipation law and is Galilean invariant, consists of coupled Navier-Stokes and Cahn-Hilliard equations. Modified General Navier Boundary Condition with fluid elasticity taken into account is also introduced for using the model to study moving contact line problems. Energy stable numerical scheme is developed to solve system of model equations efficiently. Convergence of the numerical scheme is verified by simulating a droplet sliding on an inclined plane under gravity. The model can be applied for studying various biological or biophysical problems. Predictive abilities of the model are demonstrated by simulating deformation of venous blood clots with different visco-elastic properties and experimentally observed internal structures under different biologically relevant shear blood flow conditions.

Entities:  

Keywords:  Energetic Variational Approach; Phase field method; deformation of blood clot; multi-phase flow; slip boundary condition; thrombus; variable density; visco-elasticity

Year:  2018        PMID: 33868491      PMCID: PMC8049542          DOI: 10.4208/cicp.oa-2017-0167

Source DB:  PubMed          Journal:  Commun Comput Phys        ISSN: 1815-2406            Impact factor:   3.246


  23 in total

1.  A multiscale model of venous thrombus formation with surface-mediated control of blood coagulation cascade.

Authors:  Zhiliang Xu; Joshua Lioi; Jian Mu; Malgorzata M Kamocka; Xiaomin Liu; Danny Z Chen; Elliot D Rosen; Mark Alber
Journal:  Biophys J       Date:  2010-05-19       Impact factor: 4.033

2.  A systems approach to hemostasis: 3. Thrombus consolidation regulates intrathrombus solute transport and local thrombin activity.

Authors:  Timothy J Stalker; John D Welsh; Maurizio Tomaiuolo; Jie Wu; Thomas V Colace; Scott L Diamond; Lawrence F Brass
Journal:  Blood       Date:  2014-06-20       Impact factor: 22.113

3.  Mathematical modeling of blood clot fragmentation during flow-mediated thrombolysis.

Authors:  Franci Bajd; Igor Serša
Journal:  Biophys J       Date:  2013-03-05       Impact factor: 4.033

4.  Estimating the viscoelastic modulus of a thrombus using an ultrasonic shear-wave approach.

Authors:  Chih-Chung Huang; Pay-Yu Chen; Cho-Chiang Shih
Journal:  Med Phys       Date:  2013-04       Impact factor: 4.071

5.  A constitutive model for a maturing fibrin network.

Authors:  Thomas H S van Kempen; Arjen C B Bogaerds; Gerrit W M Peters; Frans N van de Vosse
Journal:  Biophys J       Date:  2014-07-15       Impact factor: 4.033

6.  Specific gravity of blood and plasma at 4 and 37 degrees C.

Authors:  R J Trudnowski; R C Rico
Journal:  Clin Chem       Date:  1974-05       Impact factor: 8.327

7.  Fibrin network structure and clot mechanical properties are altered by incorporation of erythrocytes.

Authors:  Kathryn C Gersh; Chandrasekaran Nagaswami; John W Weisel
Journal:  Thromb Haemost       Date:  2009-12       Impact factor: 5.249

8.  Cellular procoagulant activity dictates clot structure and stability as a function of distance from the cell surface.

Authors:  Robert A Campbell; Katherine A Overmyer; C Robert Bagnell; Alisa S Wolberg
Journal:  Arterioscler Thromb Vasc Biol       Date:  2008-10-30       Impact factor: 8.311

Review 9.  Fibrin clot structure and function: a role in the pathophysiology of arterial and venous thromboembolic diseases.

Authors:  Anetta Undas; Robert A S Ariëns
Journal:  Arterioscler Thromb Vasc Biol       Date:  2011-08-11       Impact factor: 8.311

10.  Blood viscosity during coagulation at different shear rates.

Authors:  Marco Ranucci; Tommaso Laddomada; Matteo Ranucci; Ekaterina Baryshnikova
Journal:  Physiol Rep       Date:  2014-07-03
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