Literature DB >> 33860809

[Osteosarcopenia].

M Drey1, R Schmidmaier2.   

Abstract

Osteoporosis is nowadays understood as an increased risk of fractures, with bone density measurement by dual-energy X‑ray absorptiometry (DXA) being a useful diagnostic criterion and a potent fracture predictor; however, especially in geriatric patients the result is often falsely negative, so that the diagnosis, indications for treatment and treatment selection should be based on an overall clinical evaluation of the individual situation. Sarcopenia is defined as a geriatric syndrome characterized by a generalized loss of skeletal mass and muscle function. Sarcopenia is associated with an increased likelihood of adverse outcomes including falls, fractures, disability and mortality. Since 2018 it is possible in Germany to encode sarcopenia in the International Statistical Classification of Diseases and Related Health Problems, 10th revision, German modification (ICD-10-GM, M62.50). In the case of a high fracture risk and indications for the presence of sarcopenia, the whole body composition should be assessed by DXA within the framework of the measurement of bone mineral density. In the treatment of osteosarcopenia non-pharmacological measures must be initiated in addition to pharmacological measures. It is particularly important to clarify and if necessary to resolve the cause of falls resulting in fractures as well as to regularly reevaluate the treatment goals.

Entities:  

Keywords:  Dual-energy X‑ray absorptiometry; Falls; Geriatrics; Osteoporosis; Sarcopenia

Year:  2021        PMID: 33860809     DOI: 10.1007/s00108-021-01025-w

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  26 in total

1.  Consensus on cachexia definitions.

Authors:  Josep M Argilés; Stefan D Anker; William J Evans; John E Morley; Ken C H Fearon; Florian Strasser; Maurizio Muscaritoli; Vicky E Baracos
Journal:  J Am Med Dir Assoc       Date:  2010-05       Impact factor: 4.669

2.  Motoneuron loss is associated with sarcopenia.

Authors:  Michael Drey; Benjamin Krieger; Cornel C Sieber; Jürgen M Bauer; Stefan Hettwer; Thomas Bertsch
Journal:  J Am Med Dir Assoc       Date:  2014-03-18       Impact factor: 4.669

3.  German Version of SARC-F: Translation, Adaption, and Validation.

Authors:  Michael Drey; Uta Ferrari; Marina Schraml; Wolfgang Kemmler; Daniel Schoene; Anna Franke; Ellen Freiberger; Robert Kob; Cornel Sieber
Journal:  J Am Med Dir Assoc       Date:  2020-01-21       Impact factor: 4.669

Review 4.  Understanding sarcopenia as a geriatric syndrome.

Authors:  Alfonso J Cruz-Jentoft; Francesco Landi; Eva Topinková; Jean-Pierre Michel
Journal:  Curr Opin Clin Nutr Metab Care       Date:  2010-01       Impact factor: 4.294

5.  Assessment of Bone and Muscle Measurements by Peripheral Quantitative Computed Tomography in Geriatric Patients.

Authors:  M Drey; M Henkel; S Petermeise; S Weiß; U Ferrari; M Rottenkolber; R Schmidmaier
Journal:  J Clin Densitom       Date:  2018-10-12       Impact factor: 2.617

6.  Muscle loss: The new malnutrition challenge in clinical practice.

Authors:  F Landi; M Camprubi-Robles; D E Bear; T Cederholm; V Malafarina; A A Welch; A J Cruz-Jentoft
Journal:  Clin Nutr       Date:  2018-11-30       Impact factor: 7.324

7.  Osteosarcopenia is more than sarcopenia and osteopenia alone.

Authors:  Michael Drey; Cornel C Sieber; Thomas Bertsch; Jürgen M Bauer; Ralf Schmidmaier
Journal:  Aging Clin Exp Res       Date:  2015-11-12       Impact factor: 3.636

8.  Effects of a vitamin D and leucine-enriched whey protein nutritional supplement on measures of sarcopenia in older adults, the PROVIDE study: a randomized, double-blind, placebo-controlled trial.

Authors:  Jürgen M Bauer; Sjors Verlaan; Ivan Bautmans; Kirsten Brandt; Lorenzo M Donini; Marcello Maggio; Marion E T McMurdo; Tony Mets; Chris Seal; Sander L Wijers; Gian Paolo Ceda; Giuseppe De Vito; Gilbert Donders; Michael Drey; Carolyn Greig; Ulf Holmbäck; Marco Narici; Jamie McPhee; Eleonora Poggiogalle; Dermot Power; Aldo Scafoglieri; Ralf Schultz; Cornel C Sieber; Tommy Cederholm
Journal:  J Am Med Dir Assoc       Date:  2015-07-10       Impact factor: 4.669

9.  Sarcopenia: revised European consensus on definition and diagnosis.

Authors:  Alfonso J Cruz-Jentoft; Gülistan Bahat; Jürgen Bauer; Yves Boirie; Olivier Bruyère; Tommy Cederholm; Cyrus Cooper; Francesco Landi; Yves Rolland; Avan Aihie Sayer; Stéphane M Schneider; Cornel C Sieber; Eva Topinkova; Maurits Vandewoude; Marjolein Visser; Mauro Zamboni
Journal:  Age Ageing       Date:  2019-01-01       Impact factor: 10.668

Review 10.  High Versus low Dietary Protein Intake and Bone Health in Older Adults: a Systematic Review and Meta-Analysis.

Authors:  Inge Groenendijk; Laura den Boeft; Luc J C van Loon; Lisette C P G M de Groot
Journal:  Comput Struct Biotechnol J       Date:  2019-07-22       Impact factor: 7.271

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