PURPOSE OF REVIEW: Highly prevalent in the population older than 65 years and leading to poor outcomes (functional decline and its related consequences), sarcopenia does not benefit yet either of a clear understanding of its pathophysiology or of precise clinical or biological markers allowing its identification. RECENT FINDINGS: The new scientific definition of 'geriatric syndromes' challenges the authors to review the current sarcopenia literature, allowing them to affirm that sarcopenia cannot be considered as an age-related disease but as a true 'geriatric syndrome'. More than 50% of the population older than 80 years suffer from this medical condition, which is linked to multiple causations: the ageing process itself, genetic susceptibility, certain life habits, changes in living conditions and a number of chronic diseases. Moreover, sarcopenia favours poor outcomes such as mobility disorders, disability, poor quality of life and death. SUMMARY: Considering sarcopenia as a geriatric syndrome allows us to request its recognition and assess its multiple risk factors, to implement a clinical and public health approach to the management of sarcopenic patients and population at risk and to disentangle the links among sarcopenia, frailty, disability and mortality.
PURPOSE OF REVIEW: Highly prevalent in the population older than 65 years and leading to poor outcomes (functional decline and its related consequences), sarcopenia does not benefit yet either of a clear understanding of its pathophysiology or of precise clinical or biological markers allowing its identification. RECENT FINDINGS: The new scientific definition of 'geriatric syndromes' challenges the authors to review the current sarcopenia literature, allowing them to affirm that sarcopenia cannot be considered as an age-related disease but as a true 'geriatric syndrome'. More than 50% of the population older than 80 years suffer from this medical condition, which is linked to multiple causations: the ageing process itself, genetic susceptibility, certain life habits, changes in living conditions and a number of chronic diseases. Moreover, sarcopenia favours poor outcomes such as mobility disorders, disability, poor quality of life and death. SUMMARY: Considering sarcopenia as a geriatric syndrome allows us to request its recognition and assess its multiple risk factors, to implement a clinical and public health approach to the management of sarcopenic patients and population at risk and to disentangle the links among sarcopenia, frailty, disability and mortality.
Authors: F Landi; R Calvani; E Ortolani; S Salini; A M Martone; L Santoro; A Santoliquido; A Sisto; A Picca; E Marzetti Journal: Osteoporos Int Date: 2017-02-02 Impact factor: 4.507
Authors: M Halil; Z Ulger; M Varlı; A Döventaş; G B Oztürk; M E Kuyumcu; B B Yavuz; Y Yesil; F Tufan; M Cankurtaran; B Saka; S Sahin; A Curgunlu; N Tekin; F Akçiçek; M A Karan; T Atlı; T Beger; D S Erdinçler; S Arıoğul Journal: Eur J Clin Nutr Date: 2014-02-26 Impact factor: 4.016
Authors: R M Alfonso-Rosa; B Del Pozo-Cruz; J Del Pozo-Cruz; J T Del Pozo-Cruz; B Sañudo Journal: J Nutr Health Aging Date: 2013-04 Impact factor: 4.075
Authors: Alfonso J Cruz-Jentoft; Jean Pierre Baeyens; Jürgen M Bauer; Yves Boirie; Tommy Cederholm; Francesco Landi; Finbarr C Martin; Jean-Pierre Michel; Yves Rolland; Stéphane M Schneider; Eva Topinková; Maurits Vandewoude; Mauro Zamboni Journal: Age Ageing Date: 2010-04-13 Impact factor: 10.668