Na Shi1,2, Chunli Zhao3, Chenglong Fang2, Dongning Zhang4, Zhou Zhou4, Gang Ouyang5. 1. Second Clinical College, Nanjing University of Chinese Medicine Nanjing, Jiangsu Province, China. 2. Department of Rehabilitation, Linyi People's Hospital Linyi, Shandong Province, China. 3. The Second Department of Stroke, Tai'an Second Hospital of TCM Tai'an, Shandong Province, China. 4. Department of Rehabilitation, Linyi People's Hospital Affiliated to The 11th Clinical Medical College of Qingdao University Linyi, Shandong Province, China. 5. Department of Traditional Medicine, Jiangsu Province Geriatric Hospital Nanjing, Jiangsu Province, China.
Abstract
OBJECTIVE: To study the effect and mechanism of acupoint catgut embedding on patients of postmenopausal osteoporosis (PMOP). METHODS: In this prospective study, 90 patients with PMOP who received treatment in our hospital were randomly divided into the drug treatment group (n=45) and drug treatment + catgut embedding group (n=45) according to SPSS random table method. The drug treatment group was given conventional western medicine treatment, and the drug treatment + catgut embedding group was given point embedding therapy. Bone mineral density (BMD), calcium (Ca2+), osteoprotegerin (OPG), estrogen (E2), receptor activator of nuclear factor-kB ligand (RANKL), liver and kidney function and blood lipids were detected before treatment in the two groups, and visual analogue score (VAS) and PMOP symptom score were evaluated. The above-mentioned indexes were detected again 3 months and 6 months after treatment. RESULTS: At 3 and 6 months after treatment, the BMD and the levels of Ca2+ and E2 in the two groups were increased, while the levels of OPG and RANKL were decreased, and the improvement in the drug treatment + catgut embedding group was significantly better than that in the drug treatment group (P<0.05). The symptom scores of VAS and PMOP in the drug treatment + catgut embedding group were significantly lower than those in the drug treatment group (all P<0.001). There was no significant difference in the levels of alanine aminotransferase (ALT), total bilirubin (TBil), albumin (ALB), blood urea nitrogen (BUN), serum creatinine (SCr) and serum uric acid (SUA) between the two groups, but the levels of total cholesterol (TC) and triglyceride (TG) in the drug treatment + catgut embedding group were significantly lower than those in the drug treatment group (all P<0.001). CONCLUSION:Acupoint catgut embedding has a good effect on PMOP, and it can increase BMO and improve the clinical symptoms of patients, which is worthy of clinical promotion. AJTR
RCT Entities:
OBJECTIVE: To study the effect and mechanism of acupoint catgut embedding on patients of postmenopausal osteoporosis (PMOP). METHODS: In this prospective study, 90 patients with PMOP who received treatment in our hospital were randomly divided into the drug treatment group (n=45) and drug treatment + catgut embedding group (n=45) according to SPSS random table method. The drug treatment group was given conventional western medicine treatment, and the drug treatment + catgut embedding group was given point embedding therapy. Bone mineral density (BMD), calcium (Ca2+), osteoprotegerin (OPG), estrogen (E2), receptor activator of nuclear factor-kB ligand (RANKL), liver and kidney function and blood lipids were detected before treatment in the two groups, and visual analogue score (VAS) and PMOP symptom score were evaluated. The above-mentioned indexes were detected again 3 months and 6 months after treatment. RESULTS: At 3 and 6 months after treatment, the BMD and the levels of Ca2+ and E2 in the two groups were increased, while the levels of OPG and RANKL were decreased, and the improvement in the drug treatment + catgut embedding group was significantly better than that in the drug treatment group (P<0.05). The symptom scores of VAS and PMOP in the drug treatment + catgut embedding group were significantly lower than those in the drug treatment group (all P<0.001). There was no significant difference in the levels of alanine aminotransferase (ALT), total bilirubin (TBil), albumin (ALB), blood ureanitrogen (BUN), serum creatinine (SCr) and serum uric acid (SUA) between the two groups, but the levels of total cholesterol (TC) and triglyceride (TG) in the drug treatment + catgut embedding group were significantly lower than those in the drug treatment group (all P<0.001). CONCLUSION: Acupoint catgut embedding has a good effect on PMOP, and it can increase BMO and improve the clinical symptoms of patients, which is worthy of clinical promotion. AJTR
Authors: Karine Briot; Christian Roux; Thierry Thomas; Hubert Blain; Daniel Buchon; Roland Chapurlat; Françoise Debiais; Jean Marc Feron; Jean Bernard Gauvain; Pascal Guggenbuhl; Eric Legrand; Anne Marie Lehr-Drylewicz; Eric Lespessailles; Florence Tremollieres; Georges Weryha; Bernard Cortet Journal: Joint Bone Spine Date: 2018-04-11 Impact factor: 4.929