Giulia Ogliari1, Jesper Ryg2,3, Karen Andersen-Ranberg2,3,4, Lasse Lybecker Scheel-Hincke4, Tahir Masud5,2. 1. Department of Health Care for Older People (HCOP), Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Derby Road, Nottingham, Nottinghamshire, NG7 2UH, UK. giulia.ogliari@virgilio.it. 2. Department of Geriatric Medicine, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense, Denmark. 3. Geriatric Research Unit, Department of Clinical Research, University of Southern Denmark, Sdr. Boulevard 29, 5000, Odense, Denmark. 4. Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, J.B. Winslowvej 9B, 5000, Odense, Denmark. 5. Department of Health Care for Older People (HCOP), Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Derby Road, Nottingham, Nottinghamshire, NG7 2UH, UK.
Abstract
PURPOSE: To investigate the longitudinal associations between body mass index (BMI) categories and falls risk in men and women. METHODS: Prospective cohort study using data from 50,041 community-dwelling adults aged ≥ 50 years assessed in Wave 6 and 7 in the cross-national Survey of Health, Ageing and Retirement in Europe (SHARE). Socio-demographic and clinical factors were assessed at baseline (Wave 6). Functional impairment was defined by any limitations in activities of daily living (ADL) or instrumental ADL (IADL). Participants were classified as underweight, normal weight, overweight or obese at baseline. At 2-year follow-up (Wave 7), falls in the previous six months were recorded. The longitudinal associations between BMI categories and falls were analysed by binary logistic regression models; odds ratios (OR) and 95% confidence intervals (CI) were calculated. All analyses were adjusted for socio-demographic and clinical factors. Furthermore, analyses were stratified by sex, age and functional impairment. RESULTS: Mean age was 67.0 years (range 50-102); 28,132 participants were women; 4057 (8.1%) participants reported falls at follow-up. Participants had an increased falls risk [OR (95% CI)] if they were underweight [1.41 (1.06-1.88), p = 0.017] or obese [1.20 (1.09-1.32), p < 0.001] compared to those with normal weight. The association of underweight and obesity with increased falls risk was consistent in participants aged ≥ 65 years. In participants with functional impairment, underweight was associated with higher falls risk [1.61 (1.09-2.40), p = 0.018], while obesity was not. CONCLUSION: A U-shaped relationship between BMI and falls risk was found in community-dwelling adults.
PURPOSE: To investigate the longitudinal associations between body mass index (BMI) categories and falls risk in men and women. METHODS: Prospective cohort study using data from 50,041 community-dwelling adults aged ≥ 50 years assessed in Wave 6 and 7 in the cross-national Survey of Health, Ageing and Retirement in Europe (SHARE). Socio-demographic and clinical factors were assessed at baseline (Wave 6). Functional impairment was defined by any limitations in activities of daily living (ADL) or instrumental ADL (IADL). Participants were classified as underweight, normal weight, overweight or obese at baseline. At 2-year follow-up (Wave 7), falls in the previous six months were recorded. The longitudinal associations between BMI categories and falls were analysed by binary logistic regression models; odds ratios (OR) and 95% confidence intervals (CI) were calculated. All analyses were adjusted for socio-demographic and clinical factors. Furthermore, analyses were stratified by sex, age and functional impairment. RESULTS: Mean age was 67.0 years (range 50-102); 28,132 participants were women; 4057 (8.1%) participants reported falls at follow-up. Participants had an increased falls risk [OR (95% CI)] if they were underweight [1.41 (1.06-1.88), p = 0.017] or obese [1.20 (1.09-1.32), p < 0.001] compared to those with normal weight. The association of underweight and obesity with increased falls risk was consistent in participants aged ≥ 65 years. In participants with functional impairment, underweight was associated with higher falls risk [1.61 (1.09-2.40), p = 0.018], while obesity was not. CONCLUSION: A U-shaped relationship between BMI and falls risk was found in community-dwelling adults.
Authors: Stefano Volpato; Suzanne G Leveille; Caroline Blaum; Linda P Fried; Jack M Guralnik Journal: J Gerontol A Biol Sci Med Sci Date: 2005-12 Impact factor: 6.053
Authors: G A Handrigan; N Maltais; M Gagné; P Lamontagne; D Hamel; N Teasdale; O Hue; P Corbeil; J P Brown; S Jean Journal: Osteoporos Int Date: 2016-08-25 Impact factor: 4.507
Authors: Elizabeth R Hooker; Smriti Shrestha; Christine G Lee; Peggy M Cawthon; Melanie Abrahamson; Kris Ensrud; Marcia L Stefanick; Thuy-Tien Dam; Lynn M Marshall; Eric S Orwoll; Carrie M Nielson Journal: J Aging Health Date: 2016-07-27
Authors: Shawna Follis; Alan Cook; Jennifer W Bea; Scott B Going; Deepika Laddu; Jane A Cauley; Aladdin H Shadyab; Marcia L Stefanick; Zhao Chen Journal: J Am Geriatr Soc Date: 2018-10-30 Impact factor: 5.562
Authors: Louis Jacob; Jae Il Shin; Karel Kostev; Josep Maria Haro; Guillermo F López-Sánchez; Lee Smith; Ai Koyanagi Journal: J Clin Med Date: 2022-07-31 Impact factor: 4.964