Elizabeth R Hooker1, Smriti Shrestha1,2, Christine G Lee3, Peggy M Cawthon4,5, Melanie Abrahamson1, Kris Ensrud6, Marcia L Stefanick7, Thuy-Tien Dam8, Lynn M Marshall1, Eric S Orwoll1, Carrie M Nielson1. 1. 1 Oregon Health & Science University, Portland, USA. 2. 2 North Carolina Agricultural and Technical State University, Greensboro, USA. 3. 3 Portland Veterans Affairs Medical Center, OR, USA. 4. 4 California Pacific Medical Center Research Institute, San Francisco, USA. 5. 5 University of California, San Francisco, USA. 6. 6 University of Minnesota, Minneapolis, USA. 7. 7 Stanford University School of Medicine, CA, USA. 8. 8 Columbia University Medical Center, New York, NY, USA.
Abstract
OBJECTIVE: The aim of this study is to evaluate fall rates across body mass index (BMI) categories by age group, considering physical performance and comorbidities. METHOD: In the Osteoporotic Fractures in Men (MrOS) study, 5,834 men aged ≥65 reported falls every 4 months over 4.8 (±0.8) years. Adjusted associations between BMI and an incident fall were tested using mixed-effects models. RESULTS: The fall rate (0.66/man-year overall, 95% confidence interval [CI] = [0.65, 0.67]) was lowest in the youngest, normal weight men (0.44/man-year, 95% CI = [0.41, 0.47]) and greatest in the oldest, highest BMI men (1.47 falls/man-year, 95% CI = [1.22, 1.76]). Obesity was associated with a 24% to 92% increased fall risk in men below 80 ( ptrend ≤ .0001, p for interaction by age = .03). Only adjustment for dynamic balance test altered the BMI-falls association substantially. DISCUSSION: Obesity was independently associated with higher fall rates in men 65 to 80 years old. Narrow walk time, a measure of gait stability, may mediate the association.
OBJECTIVE: The aim of this study is to evaluate fall rates across body mass index (BMI) categories by age group, considering physical performance and comorbidities. METHOD: In the Osteoporotic Fractures in Men (MrOS) study, 5,834 men aged ≥65 reported falls every 4 months over 4.8 (±0.8) years. Adjusted associations between BMI and an incident fall were tested using mixed-effects models. RESULTS: The fall rate (0.66/man-year overall, 95% confidence interval [CI] = [0.65, 0.67]) was lowest in the youngest, normal weight men (0.44/man-year, 95% CI = [0.41, 0.47]) and greatest in the oldest, highest BMI men (1.47 falls/man-year, 95% CI = [1.22, 1.76]). Obesity was associated with a 24% to 92% increased fall risk in men below 80 ( ptrend ≤ .0001, p for interaction by age = .03). Only adjustment for dynamic balance test altered the BMI-falls association substantially. DISCUSSION: Obesity was independently associated with higher fall rates in men 65 to 80 years old. Narrow walk time, a measure of gait stability, may mediate the association.
Authors: Christine G Lee; Edward J Boyko; Carrie M Nielson; Marcia L Stefanick; Douglas C Bauer; Andrew R Hoffman; Thuy-Tien L Dam; Jodi A Lapidus; Peggy Mannen Cawthon; Kristine E Ensrud; Eric S Orwoll Journal: J Am Geriatr Soc Date: 2011-02-02 Impact factor: 5.562
Authors: Eric Orwoll; Janet Babich Blank; Elizabeth Barrett-Connor; Jane Cauley; Steven Cummings; Kristine Ensrud; Cora Lewis; Peggy M Cawthon; Robert Marcus; Lynn M Marshall; Joan McGowan; Kathy Phipps; Sherry Sherman; Marcia L Stefanick; Katie Stone Journal: Contemp Clin Trials Date: 2005-10 Impact factor: 2.226
Authors: Kimberly A Faulkner; Jane A Cauley; Joseph M Zmuda; Douglas P Landsittel; Michael C Nevitt; Anne B Newman; Stephanie A Studenski; Mark S Redfern Journal: J Am Geriatr Soc Date: 2005-10 Impact factor: 5.562
Authors: Sharon W Renner; Jane A Cauley; Patrick J Brown; Robert M Boudreau; Todd M Bear; Terri Blackwell; Nancy E Lane; Nancy W Glynn Journal: Innov Aging Date: 2020-11-27