Literature DB >> 33816885

On-demand virtual research environments using microservices.

Marco Capuccini1,2, Anders Larsson3, Matteo Carone2, Jon Ander Novella3, Noureddin Sadawi4, Jianliang Gao4, Salman Toor1, Ola Spjuth2.   

Abstract

The computational demands for scientific applications are continuously increasing. The emergence of cloud computing has enabled on-demand resource allocation. However, relying solely on infrastructure as a service does not achieve the degree of flexibility required by the scientific community. Here we present a microservice-oriented methodology, where scientific applications run in a distributed orchestration platform as software containers, referred to as on-demand, virtual research environments. The methodology is vendor agnostic and we provide an open source implementation that supports the major cloud providers, offering scalable management of scientific pipelines. We demonstrate applicability and scalability of our methodology in life science applications, but the methodology is general and can be applied to other scientific domains. ©2019 Capuccini et al.

Entities:  

Keywords:  Application containers; Cloud computing; Microservices; Orchestration; Virtual research environments

Year:  2019        PMID: 33816885      PMCID: PMC7924445          DOI: 10.7717/peerj-cs.232

Source DB:  PubMed          Journal:  PeerJ Comput Sci        ISSN: 2376-5992


  16 in total

1.  Searching molecular structure databases with tandem mass spectra using CSI:FingerID.

Authors:  Kai Dührkop; Huibin Shen; Marvin Meusel; Juho Rousu; Sebastian Böcker
Journal:  Proc Natl Acad Sci U S A       Date:  2015-09-21       Impact factor: 11.205

2.  Tracking the NGS revolution: managing life science research on shared high-performance computing clusters.

Authors:  Martin Dahlö; Douglas G Scofield; Wesley Schaal; Ola Spjuth
Journal:  Gigascience       Date:  2018-05-01       Impact factor: 6.524

3.  Improving global feature detectabilities through scan range splitting for untargeted metabolomics by high-performance liquid chromatography-Orbitrap mass spectrometry.

Authors:  Christina Ranninger; Lukas E Schmidt; Marc Rurik; Alice Limonciel; Paul Jennings; Oliver Kohlbacher; Christian G Huber
Journal:  Anal Chim Acta       Date:  2016-05-25       Impact factor: 6.558

4.  Multi-Ethnic Study of Atherosclerosis: objectives and design.

Authors:  Diane E Bild; David A Bluemke; Gregory L Burke; Robert Detrano; Ana V Diez Roux; Aaron R Folsom; Philip Greenland; David R Jacob; Richard Kronmal; Kiang Liu; Jennifer Clark Nelson; Daniel O'Leary; Mohammed F Saad; Steven Shea; Moyses Szklo; Russell P Tracy
Journal:  Am J Epidemiol       Date:  2002-11-01       Impact factor: 4.897

5.  Workflow for Integrated Processing of Multicohort Untargeted 1H NMR Metabolomics Data in Large-Scale Metabolic Epidemiology.

Authors:  Ibrahim Karaman; Diana L S Ferreira; Claire L Boulangé; Manuja R Kaluarachchi; David Herrington; Anthony C Dona; Raphaële Castagné; Alireza Moayyeri; Benjamin Lehne; Marie Loh; Paul S de Vries; Abbas Dehghan; Oscar H Franco; Albert Hofman; Evangelos Evangelou; Ioanna Tzoulaki; Paul Elliott; John C Lindon; Timothy M D Ebbels
Journal:  J Proteome Res       Date:  2016-10-06       Impact factor: 4.466

6.  Lessons learned from implementing a national infrastructure in Sweden for storage and analysis of next-generation sequencing data.

Authors:  Samuel Lampa; Martin Dahlö; Pall I Olason; Jonas Hagberg; Ola Spjuth
Journal:  Gigascience       Date:  2013-06-25       Impact factor: 6.524

7.  Singularity: Scientific containers for mobility of compute.

Authors:  Gregory M Kurtzer; Vanessa Sochat; Michael W Bauer
Journal:  PLoS One       Date:  2017-05-11       Impact factor: 3.240

8.  PhenoMeNal: processing and analysis of metabolomics data in the cloud.

Authors:  Kristian Peters; James Bradbury; Sven Bergmann; Marco Capuccini; Marta Cascante; Pedro de Atauri; Timothy M D Ebbels; Carles Foguet; Robert Glen; Alejandra Gonzalez-Beltran; Ulrich L Günther; Evangelos Handakas; Thomas Hankemeier; Kenneth Haug; Stephanie Herman; Petr Holub; Massimiliano Izzo; Daniel Jacob; David Johnson; Fabien Jourdan; Namrata Kale; Ibrahim Karaman; Bita Khalili; Payam Emami Khonsari; Kim Kultima; Samuel Lampa; Anders Larsson; Christian Ludwig; Pablo Moreno; Steffen Neumann; Jon Ander Novella; Claire O'Donovan; Jake T M Pearce; Alina Peluso; Marco Enrico Piras; Luca Pireddu; Michelle A C Reed; Philippe Rocca-Serra; Pierrick Roger; Antonio Rosato; Rico Rueedi; Christoph Ruttkies; Noureddin Sadawi; Reza M Salek; Susanna-Assunta Sansone; Vitaly Selivanov; Ola Spjuth; Daniel Schober; Etienne A Thévenot; Mattia Tomasoni; Merlijn van Rijswijk; Michael van Vliet; Mark R Viant; Ralf J M Weber; Gianluigi Zanetti; Christoph Steinbeck
Journal:  Gigascience       Date:  2019-02-01       Impact factor: 6.524

9.  MetaboLights--an open-access general-purpose repository for metabolomics studies and associated meta-data.

Authors:  Kenneth Haug; Reza M Salek; Pablo Conesa; Janna Hastings; Paula de Matos; Mark Rijnbeek; Tejasvi Mahendraker; Mark Williams; Steffen Neumann; Philippe Rocca-Serra; Eamonn Maguire; Alejandra González-Beltrán; Susanna-Assunta Sansone; Julian L Griffin; Christoph Steinbeck
Journal:  Nucleic Acids Res       Date:  2012-10-29       Impact factor: 16.971

10.  Container-based bioinformatics with Pachyderm.

Authors:  Jon Ander Novella; Payam Emami Khoonsari; Stephanie Herman; Daniel Whitenack; Marco Capuccini; Joachim Burman; Kim Kultima; Ola Spjuth
Journal:  Bioinformatics       Date:  2019-03-01       Impact factor: 6.937

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