Literature DB >> 33800406

Increase in Tuberculosis Diagnostic Delay during First Wave of the COVID-19 Pandemic: Data from an Italian Infectious Disease Referral Hospital.

Francesco Di Gennaro1, Gina Gualano1, Laura Timelli1, Pietro Vittozzi1, Virginia Di Bari1, Raffaella Libertone1, Carlotta Cerva1, Luigi Pinnarelli2, Carla Nisii1, Stefania Ianniello1, Silvia Mosti1, Nazario Bevilacqua1, Fabio Iacomi1, Annalisa Mondi1, Simone Topino1, Delia Goletti1, Francesco Vaia1, Giuseppe Ippolito1, Enrico Girardi1, Fabrizio Palmieri1.   

Abstract

BACKGROUND: The WHO advised that the impact of COVID-19 pandemic on TB services was estimated to be dramatic due to the disruption of TB services.
METHODS: A retrospective data collection and evaluation was conducted to include all the patients hospitalized for TB at INMI from 9 March to 31 August 2020 (lockdown period and three months thereafter). For the purpose of the study, data from patients hospitalized in the same period of 2019 were also collected.
RESULTS: In the period of March-August 2019, 201 patients were hospitalized with a diagnosis of TB, while in the same period of 2020, only 115 patients, with a case reduction of 43%. Patients with weight loss, acute respiratory failure, concurrent extrapulmonary TB, and higher Timika radiographic scores were significantly more frequently hospitalized during 2020 vs. 2019. The median patient delay was 75 days (IQR: 40-100) in 2020 compared to 30 days (IQR: 10-60) in 2019 (p < 0.01). Diagnostic delays in 2020 remain significant in the multiple logistic model (AOR = 6.93, 95%CI: 3.9-12.3).
CONCLUSIONS: Our experience suggests that COVID-19 pandemic had an impact on TB patient care in terms of higher diagnostic delay, reduction in hospitalization, and a greater severity of clinical presentations.

Entities:  

Keywords:  COVID 19; SARS CoV2; diagnostic delay; pandemic; tuberculosis

Year:  2021        PMID: 33800406      PMCID: PMC7998965          DOI: 10.3390/antibiotics10030272

Source DB:  PubMed          Journal:  Antibiotics (Basel)        ISSN: 2079-6382


  29 in total

1.  Increase in disseminated TB during the COVID-19 pandemic.

Authors:  J Barrett; H Painter; A Rajgopal; D Keane; L John; P Papineni; A Whittington
Journal:  Int J Tuberc Lung Dis       Date:  2021-02-01       Impact factor: 2.373

2.  Reader variability and validation of the Timika X-ray score during treatment of pulmonary tuberculosis.

Authors:  B A Thiel; C M Bark; J G Nakibali; F van der Kuyp; J L Johnson
Journal:  Int J Tuberc Lung Dis       Date:  2016-10       Impact factor: 2.373

3.  A decrease in tuberculosis evaluations and diagnoses during the COVID-19 pandemic.

Authors:  J K Louie; M Reid; J Stella; R Agraz-Lara; S Graves; L Chen; P Hopewell
Journal:  Int J Tuberc Lung Dis       Date:  2020-08-01       Impact factor: 2.373

4.  Cancer diagnostic rates during the 2020 'lockdown', due to COVID-19 pandemic, compared with the 2018-2019: an audit study from cellular pathology.

Authors:  Ludovica De Vincentiis; Richard A Carr; Maria Paola Mariani; Gerardo Ferrara
Journal:  J Clin Pathol       Date:  2020-06-19       Impact factor: 3.411

Review 5.  Delays in diagnosis and treatment of pulmonary tuberculosis in India: a systematic review.

Authors:  Chandrashekhar T Sreeramareddy; Zhi Zhen Qin; Srinath Satyanarayana; Ramnath Subbaraman; Madhukar Pai
Journal:  Int J Tuberc Lung Dis       Date:  2014-03       Impact factor: 2.373

Review 6.  Social determinants of therapy failure and multi drug resistance among people with tuberculosis: A review.

Authors:  Francesco Di Gennaro; Damiano Pizzol; Bonifacio Cebola; Brendon Stubbs; Laura Monno; Annalisa Saracino; Claudio Luchini; Marco Solmi; Giulia Segafredo; Giovanni Putoto; Nicola Veronese
Journal:  Tuberculosis (Edinb)       Date:  2017-01-11       Impact factor: 3.131

7.  Factors associated with patient and health care system delay in the diagnosis of tuberculosis in France.

Authors:  P Tattevin; D Che; P Fraisse; C Gatey; C Guichard; D Antoine; M C Paty; E Bouvet
Journal:  Int J Tuberc Lung Dis       Date:  2012-04       Impact factor: 2.373

8.  The potential impact of the COVID-19 pandemic on the tuberculosis epidemic a modelling analysis.

Authors:  Lucia Cilloni; Han Fu; Juan F Vesga; David Dowdy; Carel Pretorius; Sevim Ahmedov; Sreenivas A Nair; Andrei Mosneaga; Enos Masini; Suvanand Sahu; Nimalan Arinaminpathy
Journal:  EClinicalMedicine       Date:  2020-10-24

9.  Magnitude, demographics and dynamics of the effect of the first wave of the COVID-19 pandemic on all-cause mortality in 21 industrialized countries.

Authors:  Vasilis Kontis; James E Bennett; Theo Rashid; Robbie M Parks; Jonathan Pearson-Stuttard; Michel Guillot; Perviz Asaria; Bin Zhou; Marco Battaglini; Gianni Corsetti; Martin McKee; Mariachiara Di Cesare; Colin D Mathers; Majid Ezzati
Journal:  Nat Med       Date:  2020-10-14       Impact factor: 53.440

Review 10.  The potential impact of COVID-19-related disruption on tuberculosis burden.

Authors:  C Finn McQuaid; Nicky McCreesh; Jonathan M Read; Tom Sumner; Rein M G J Houben; Richard G White; Rebecca C Harris
Journal:  Eur Respir J       Date:  2020-08-13       Impact factor: 16.671

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  30 in total

1.  [Translated article] Decline of Tuberculosis Rates and COVID-19 Pandemic. Fact or Fiction?

Authors:  Nuria Vázquez-Temprano; María Isabel Ursúa-Díaz; Ángel Salgado-Barreira; Rafael Vázquez-Gallardo; Victoria Túñez Bastida; Luis Anibarro
Journal:  Arch Bronconeumol       Date:  2022-02-11       Impact factor: 4.872

2.  Predictors of COVID-19 Hospital Treatment Outcome.

Authors:  Ryszard Tomasiuk; Jan Dabrowski; Jolanta Smykiewicz; Magdalena Wiacek
Journal:  Int J Gen Med       Date:  2021-12-22

3.  Time trend prediction and spatial-temporal analysis of multidrug-resistant tuberculosis in Guizhou Province, China, during 2014-2020.

Authors:  Wang Yun; Chen Huijuan; Liao Long; Lu Xiaolong; Zhang Aihua
Journal:  BMC Infect Dis       Date:  2022-06-07       Impact factor: 3.667

4.  Public Awareness, Attitudes, and Adherence to COVID-19 Quarantine and Isolation in Saudi Arabia.

Authors:  Mohammed Khamash Almaghrabi
Journal:  Int J Gen Med       Date:  2021-08-11

5.  New disease and old threats: A case series of COVID-19 and tuberculosis coinfection in Saudi Arabia.

Authors:  Mohammed Shabrawishi; Abdullmoin AlQarni; Maher Ghazawi; Baraa Melibari; Tebra Baljoon; Hassan Alwafi; Mohammed Samannodi
Journal:  Clin Case Rep       Date:  2021-05-24

6.  [Decline of Tuberculosis Rates and COVID-19 Pandemic. Fact or Fiction?]

Authors:  Nuria Vázquez-Temprano; María Isabel Ursúa-Díaz; Ángel Salgado-Barreira; Rafael Vázquez-Gallardo; Victoria Túñez Bastida; Luis Anibarro
Journal:  Arch Bronconeumol       Date:  2021-06-01       Impact factor: 6.333

7.  Limited Impact of Delta Variant's Mutations on the Effectiveness of Neutralization Conferred by Natural Infection or COVID-19 Vaccines in a Latino Population.

Authors:  Carlos A Sariol; Crisanta Serrano-Collazo; Edwin J Ortiz; Petraleigh Pantoja; Lorna Cruz; Teresa Arana; Dianne Atehortua; Christina Pabon-Carrero; Ana M Espino
Journal:  Viruses       Date:  2021-11-30       Impact factor: 5.048

8.  Integrated Tuberculosis and COVID-19 Activities in Karachi and Tuberculosis Case Notifications.

Authors:  Amyn A Malik; Hamidah Hussain; Rabia Maniar; Nauman Safdar; Amal Mohiuddin; Najam Riaz; Aneeta Pasha; Salman Khan; Syed Saleem Hasan Kazmi; Ershad Kazmi; Saira Khowaja
Journal:  Trop Med Infect Dis       Date:  2022-01-15

9.  Increased Healthcare Delays in Tuberculosis Patients During the First Wave of COVID-19 Pandemic in Korea: A Nationwide Cross-Sectional Study.

Authors:  Jinsoo Min; Yousang Ko; Hyung Woo Kim; Hyeon-Kyoung Koo; Jee Youn Oh; Yun-Jeong Jeong; Hyeon Hui Kang; Kwang Joo Park; Yong Il Hwang; Jin Woo Kim; Joong Hyun Ahn; Yangjin Jegal; Ji Young Kang; Sung-Soon Lee; Jae Seuk Park; Ju Sang Kim
Journal:  J Korean Med Sci       Date:  2022-01-17       Impact factor: 2.153

10.  Pulmonary Tuberculosis in Older Adults: Increased Mortality Related to Tuberculosis Within Two Months of Treatment Initiation.

Authors:  Isano Hase; Katelynne Gardner Toren; Hitomi Hirano; Kimiko Sakurai; David J Horne; Takefumi Saito; Masahiro Narita
Journal:  Drugs Aging       Date:  2021-07-05       Impact factor: 3.923

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