Literature DB >> 33796561

Androgenetic Alopecia in a Patient with Klinefelter Syndrome: Case Report and Literature Review.

Waleed Alsalhi1, Antonella Tosti2.   

Abstract

INTRODUCTION: Klinefelter syndrome (KS) is defined as (a chromosomal disorder in which males have an extra X chromosome). KS presents clinically with signs of androgen deficiency including low testosterone. Androgenetic alopecia (AGA) develops as a response of the hair follicle cells to androgens in individuals with genetic predisposition. CASE
PRESENTATION: We describe a 17-year-old male patient with KS who developed AGA with a Ludwig pattern.
CONCLUSION: Our patient had a good response to oral minoxidil, finasteride, and low-level light therapy.
Copyright © 2020 by S. Karger AG, Basel.

Entities:  

Keywords:  Alopecia; Finasteride; Hair loss; Klinefelter syndrome; Testosterone

Year:  2020        PMID: 33796561      PMCID: PMC7991277          DOI: 10.1159/000512224

Source DB:  PubMed          Journal:  Skin Appendage Disord        ISSN: 2296-9160


  26 in total

Review 1.  Klinefelter's syndrome associated with progressive systemic sclerosis: report of a case and review of the literature.

Authors:  S Kobayashi; T Shimamoto; O Taniguchi; H Hashimoto; S Hirose
Journal:  Clin Rheumatol       Date:  1991-03       Impact factor: 2.980

2.  Association between venous leg ulcers and sex chromosome anomalies in men.

Authors:  Cornelia Gattringer; Christine Scheurecker; Reinhard Höpfl; Hansgeorg Müller
Journal:  Acta Derm Venereol       Date:  2010-11       Impact factor: 4.437

3.  [Chronic diffuse alopecia of the pseudo androgenetic type in Klinefelter's syndrome].

Authors:  O Braun-Falco; R Milbradt
Journal:  Hautarzt       Date:  1971-08       Impact factor: 0.751

4.  Loose anagen hair syndrome: Treatment with systemic minoxidil characterised by marked hair colour change.

Authors:  William C Cranwell; Rodney Sinclair
Journal:  Australas J Dermatol       Date:  2018-03-22       Impact factor: 2.875

Review 5.  Klinefelter syndrome: the commonest form of hypogonadism, but often overlooked or untreated.

Authors:  Eberhard Nieschlag
Journal:  Dtsch Arztebl Int       Date:  2013-05-17       Impact factor: 5.594

Review 6.  Incontinentia pigmenti in a male infant with Klinefelter syndrome: a case report and review of the literature.

Authors:  Evelina Buinauskaite; Jurate Buinauskiene; Vesta Kucinskiene; Dale Strazdiene; Skaidra Valiukeviciene
Journal:  Pediatr Dermatol       Date:  2010-08-27       Impact factor: 1.588

7.  Female pattern hair loss in complete androgen insensitivity syndrome.

Authors:  P Cousen; A Messenger
Journal:  Br J Dermatol       Date:  2010-02-01       Impact factor: 9.302

Review 8.  Finasteride in the treatment of alopecia.

Authors:  James F Libecco; Wilma F Bergfeld
Journal:  Expert Opin Pharmacother       Date:  2004-04       Impact factor: 3.889

9.  Klinefelter's syndrome associated with breast carcinoma and Paget's disease of the nipple.

Authors:  V Moshakis; M J Fordyce; J D Griffiths
Journal:  Clin Oncol       Date:  1983-09

10.  Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome.

Authors:  Valerie M Harris; Rohan Sharma; Joshua Cavett; Biji T Kurien; Ke Liu; Kristi A Koelsch; Astrid Rasmussen; Lida Radfar; David Lewis; Donald U Stone; C Erick Kaufman; Shibo Li; Barbara Segal; Daniel J Wallace; Michael H Weisman; Swamy Venuturupalli; Jennifer A Kelly; Marta E Alarcon-Riquelme; Bernardo Pons-Estel; Roland Jonsson; Xianglan Lu; Jacques-Eric Gottenberg; Juan-Manuel Anaya; Deborah S Cunninghame-Graham; Andrew J W Huang; Michael T Brennan; Pamela Hughes; Ilias Alevizos; Corinne Miceli-Richard; Edward C Keystone; Vivian P Bykerk; Gideon Hirschfield; Gang Xie; Katherine A Siminovitch; Wan-Fai Ng; Gunnel Nordmark; Sara Magnusson Bucher; Per Eriksson; Roald Omdal; Nelson L Rhodus; Maureen Rischmueller; Michael Rohrer; Marie Wahren-Herlenius; Torsten Witte; Xavier Mariette; Christopher J Lessard; John B Harley; Kathy L Sivils; R Hal Scofield
Journal:  Clin Immunol       Date:  2016-04-22       Impact factor: 3.969

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