Literature DB >> 33782300

18F-FDG and 68Ga-FAPI PET/CT in the Evaluation of Ground-Glass Opacity Nodule.

Haojun Chen1, Yizhen Pang1, Tinghua Meng1, Xiuyi Yu2, Long Sun1.   

Abstract

ABSTRACT: A 50-year-old woman with a newly detected pulmonary ground-glass opacity (GGO) nodule underwent PET/CT to determine the likelihood of malignancy. This patient was enrolled in the prospective study (NCT04588064) to determine the effectiveness of 18F-FDG and 68Ga-FAPI PET/CT for characterization of the GGO nodule. On PET/CT images, minimal 18F-FDG uptake but intense 68Ga-FAPI uptake was observed in this GGO nodule. This patient subsequently underwent video-assisted thoracoscopic surgery, and postoperative pathological examination confirmed the diagnosis of invasive adenocarcinoma. This case presented an example where 68Ga-FAPI PET/CT showed higher tracer uptake than 18F-FDG in the malignant GGO nodule.
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

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Year:  2021        PMID： 33782300     DOI： 10.1097/RLU.0000000000003600

Source DB:  PubMed          Journal:  Clin Nucl Med        ISSN： 0363-9762            Impact factor:   7.794


  4 in total

1.  Expression of fibroblast activation protein in lung cancer and its correlation with tumor glucose metabolism and histopathology.

Authors:  Xiaohui Chen; Xinran Liu; Lijuan Wang; Wenlan Zhou; Yin Zhang; Ying Tian; Jianer Tan; Ye Dong; Lilan Fu; Hubing Wu
Journal:  Eur J Nucl Med Mol Imaging       Date:  2022-03-07       Impact factor: 10.057

Review 2.  Clinical summary of fibroblast activation protein inhibitor-based radiopharmaceuticals: cancer and beyond.

Authors:  Mengting Li; Muhsin H Younis; Yongxue Zhang; Weibo Cai; Xiaoli Lan
Journal:  Eur J Nucl Med Mol Imaging       Date:  2022-01-31       Impact factor: 10.057

3.  Primary lung invasive adenocarcinoma misdiagnosed as infectious pneumonia in 18F-FDG PET/CT:A case report.

Authors:  Yuping Han; Yongjun Luo
Journal:  Radiol Case Rep       Date:  2021-12-31

Review 4.  Fibroblast activation protein-based theranostics in cancer research: A state-of-the-art review.

Authors:  Liang Zhao; Jianhao Chen; Yizhen Pang; Kaili Fu; Qihang Shang; Hua Wu; Long Sun; Qin Lin; Haojun Chen
Journal:  Theranostics       Date:  2022-01-09       Impact factor: 11.556
  4 in total

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