Literature DB >> 33777024

Lack of Effectiveness of Repurposed Drugs for COVID-19 Treatment.

Miguel Angel Martinez1.   

Abstract

Entities:  

Keywords:  COVID-19; HCV; HIV; repurposed drugs; treatment efficacy

Mesh：

Substances：

Year:  2021        PMID： 33777024      PMCID： PMC7990901          DOI： 10.3389/fimmu.2021.635371

Source DB:  PubMed          Journal:  Front Immunol        ISSN： 1664-3224            Impact factor:   7.561


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  24 in total

Review 1.  HIV-1 antiretroviral drug therapy.

Authors:  Eric J Arts; Daria J Hazuda
Journal:  Cold Spring Harb Perspect Med       Date:  2012-04       Impact factor: 6.915

2.  Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates.

Authors:  Pauline Maisonnasse; Jérémie Guedj; Vanessa Contreras; Sylvie Behillil; Caroline Solas; Romain Marlin; Thibaut Naninck; Andres Pizzorno; Julien Lemaitre; Antonio Gonçalves; Nidhal Kahlaoui; Olivier Terrier; Raphael Ho Tsong Fang; Vincent Enouf; Nathalie Dereuddre-Bosquet; Angela Brisebarre; Franck Touret; Catherine Chapon; Bruno Hoen; Bruno Lina; Manuel Rosa Calatrava; Sylvie van der Werf; Xavier de Lamballerie; Roger Le Grand
Journal:  Nature       Date:  2020-07-22       Impact factor: 49.962

3.  Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2.

Authors:  Markus Hoffmann; Kirstin Mösbauer; Heike Hofmann-Winkler; Artur Kaul; Hannah Kleine-Weber; Nadine Krüger; Nils C Gassen; Marcel A Müller; Christian Drosten; Stefan Pöhlmann
Journal:  Nature       Date:  2020-07-22       Impact factor: 49.962

4.  Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor.

Authors:  Jun Lan; Jiwan Ge; Jinfang Yu; Sisi Shan; Huan Zhou; Shilong Fan; Qi Zhang; Xuanling Shi; Qisheng Wang; Linqi Zhang; Xinquan Wang
Journal:  Nature       Date:  2020-03-30       Impact factor: 49.962

5.  Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial.

Authors:  Yeming Wang; Dingyu Zhang; Guanhua Du; Ronghui Du; Jianping Zhao; Yang Jin; Shouzhi Fu; Ling Gao; Zhenshun Cheng; Qiaofa Lu; Yi Hu; Guangwei Luo; Ke Wang; Yang Lu; Huadong Li; Shuzhen Wang; Shunan Ruan; Chengqing Yang; Chunlin Mei; Yi Wang; Dan Ding; Feng Wu; Xin Tang; Xianzhi Ye; Yingchun Ye; Bing Liu; Jie Yang; Wen Yin; Aili Wang; Guohui Fan; Fei Zhou; Zhibo Liu; Xiaoying Gu; Jiuyang Xu; Lianhan Shang; Yi Zhang; Lianjun Cao; Tingting Guo; Yan Wan; Hong Qin; Yushen Jiang; Thomas Jaki; Frederick G Hayden; Peter W Horby; Bin Cao; Chen Wang
Journal:  Lancet       Date:  2020-04-29       Impact factor: 79.321

6.  Neutralizing Antibodies Correlate with Protection from SARS-CoV-2 in Humans during a Fishery Vessel Outbreak with a High Attack Rate.

Authors:  Amin Addetia; Katharine H D Crawford; Adam Dingens; Haiying Zhu; Pavitra Roychoudhury; Meei-Li Huang; Keith R Jerome; Jesse D Bloom; Alexander L Greninger
Journal:  J Clin Microbiol       Date:  2020-10-21       Impact factor: 5.948

7.  The effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with non-severe COVID-19: A pilot, double-blind, placebo-controlled, randomized clinical trial.

Authors:  Carlos Chaccour; Aina Casellas; Andrés Blanco-Di Matteo; Iñigo Pineda; Alejandro Fernandez-Montero; Paula Ruiz-Castillo; Mary-Ann Richardson; Mariano Rodríguez-Mateos; Carlota Jordán-Iborra; Joe Brew; Francisco Carmona-Torre; Miriam Giráldez; Ester Laso; Juan C Gabaldón-Figueira; Carlota Dobaño; Gemma Moncunill; José R Yuste; Jose L Del Pozo; N Regina Rabinovich; Verena Schöning; Felix Hammann; Gabriel Reina; Belen Sadaba; Mirian Fernández-Alonso
Journal:  EClinicalMedicine       Date:  2021-01-19

Review 8.  Compounds with Therapeutic Potential against Novel Respiratory 2019 Coronavirus.

Authors:  Miguel Angel Martinez
Journal:  Antimicrob Agents Chemother       Date:  2020-04-21       Impact factor: 5.191

9.  A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19.

Authors:  Bin Cao; Yeming Wang; Danning Wen; Wen Liu; Jingli Wang; Guohui Fan; Lianguo Ruan; Bin Song; Yanping Cai; Ming Wei; Xingwang Li; Jiaan Xia; Nanshan Chen; Jie Xiang; Ting Yu; Tao Bai; Xuelei Xie; Li Zhang; Caihong Li; Ye Yuan; Hua Chen; Huadong Li; Hanping Huang; Shengjing Tu; Fengyun Gong; Ying Liu; Yuan Wei; Chongya Dong; Fei Zhou; Xiaoying Gu; Jiuyang Xu; Zhibo Liu; Yi Zhang; Hui Li; Lianhan Shang; Ke Wang; Kunxia Li; Xia Zhou; Xuan Dong; Zhaohui Qu; Sixia Lu; Xujuan Hu; Shunan Ruan; Shanshan Luo; Jing Wu; Lu Peng; Fang Cheng; Lihong Pan; Jun Zou; Chunmin Jia; Juan Wang; Xia Liu; Shuzhen Wang; Xudong Wu; Qin Ge; Jing He; Haiyan Zhan; Fang Qiu; Li Guo; Chaolin Huang; Thomas Jaki; Frederick G Hayden; Peter W Horby; Dingyu Zhang; Chen Wang
Journal:  N Engl J Med       Date:  2020-03-18       Impact factor: 91.245

10.  Dexamethasone in Hospitalized Patients with Covid-19.

Authors:  Peter Horby; Wei Shen Lim; Jonathan R Emberson; Marion Mafham; Jennifer L Bell; Louise Linsell; Natalie Staplin; Christopher Brightling; Andrew Ustianowski; Einas Elmahi; Benjamin Prudon; Christopher Green; Timothy Felton; David Chadwick; Kanchan Rege; Christopher Fegan; Lucy C Chappell; Saul N Faust; Thomas Jaki; Katie Jeffery; Alan Montgomery; Kathryn Rowan; Edmund Juszczak; J Kenneth Baillie; Richard Haynes; Martin J Landray
Journal:  N Engl J Med       Date:  2020-07-17       Impact factor: 91.245
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  15 in total

1.  Synthesis and In Vitro Study of Antiviral Activity of Glycyrrhizin Nicotinate Derivatives against HIV-1 Pseudoviruses and SARS-CoV-2 Viruses.

Authors:  Vladislav V Fomenko; Nadezhda B Rudometova; Olga I Yarovaya; Artem D Rogachev; Anastasia A Fando; Anna V Zaykovskaya; Nina I Komarova; Dmitry N Shcherbakov; Oleg V Pyankov; Andrey G Pokrovsky; Larisa I Karpenko; Rinat A Maksyutov; Nariman F Salakhutdinov
Journal:  Molecules       Date:  2022-01-04       Impact factor: 4.411

2.  What Should Be Learned From Repurposed Antivirals Against SARS-CoV-2?

Authors:  Miguel Angel Martinez
Journal:  Front Microbiol       Date:  2022-02-16       Impact factor: 5.640

3.  Investigation of structural analogs of hydroxychloroquine for SARS-CoV-2 main protease (Mpro): A computational drug discovery study.

Authors:  Saima Reyaz; Alvea Tasneem; Gyan Prakash Rai; Hridoy R Bairagya
Journal:  J Mol Graph Model       Date:  2021-09-09       Impact factor: 2.518

4.  Efficacy and safety of hydroxychloroquine as pre-and post-exposure prophylaxis and treatment of COVID-19: A systematic review and meta-analysis of blinded, placebo-controlled, randomized clinical trials.

Authors:  Paulo Ricardo Martins-Filho; Lis Campos Ferreira; Luana Heimfarth; Adriano Antunes de Souza Araújo; Lucindo José Quintans-Júnior
Journal:  Lancet Reg Health Am       Date:  2021-08-29

Review 5.  Strategies to identify candidate repurposable drugs: COVID-19 treatment as a case example.

Authors:  Ali S Imami; Robert E McCullumsmith; Sinead M O'Donovan
Journal:  Transl Psychiatry       Date:  2021-11-16       Impact factor: 6.222

Review 6.  Pulmonary surfactant as a versatile biomaterial to fight COVID-19.

Authors:  Lore Herman; Stefaan C De Smedt; Koen Raemdonck
Journal:  J Control Release       Date:  2021-11-20       Impact factor: 9.776

Review 7.  Marine mollusc extracts-Potential source of SARS-CoV-2 antivirals.

Authors:  Rebecca L Pedler; Peter G Speck
Journal:  Rev Med Virol       Date:  2021-11-02       Impact factor: 11.043

8.  In vitro testing and computational analysis of specific phytochemicals with antiviral activities considering their possible applications against COVID-19.

Authors:  Jovana Trifunović Ristovski; Mohammed Mahbubul Matin; Ren Kong; Milica Paut Kusturica; Hao Zhang
Journal:  S Afr J Bot       Date:  2022-02-10       Impact factor: 2.315

Review 9.  Therapeutics for COVID-19 and post COVID-19 complications: An update.

Authors:  Debdoot Basu; Vivek P Chavda; Anita A Mehta
Journal:  Curr Res Pharmacol Drug Discov       Date:  2022-02-04

10.  Role of Pegylated Interferon in Patients with Chronic Liver Diseases in the Context of SARS-CoV-2 Infection.

Authors:  Sheikh Mf Akbar; Mamun A Mahtab; Julio C Aguilar; Md H Uddin; Md Sakirul I Khan; Osamu Yoshida; Eduardo Penton; Guillen N Gerardo; Yoichi Hiasa
Journal:  Euroasian J Hepatogastroenterol       Date:  2021 Jan-Jun
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