| Literature DB >> 33774735 |
F Alberti1, E Baake2, I Letter3, S Martínez4.
Abstract
We consider the discrete-time migration-recombination equation, a deterministic, nonlinear dynamical system that describes the evolution of the genetic type distribution of a population evolving under migration and recombination in a law of large numbers setting. We relate this dynamics (forward in time) to a Markov chain, namely a labelled partitioning process, backward in time. This way, we obtain a stochastic representation of the solution of the migration-recombination equation. As a consequence, one obtains an explicit solution of the nonlinear dynamics, simply in terms of powers of the transition matrix of the Markov chain. The limiting and quasi-limiting behaviour of the Markov chain are investigated, which gives immediate access to the asymptotic behaviour of the dynamical system. We finally sketch the analogous situation in continuous time.Entities:
Keywords: Ancestral recombination graph; Duality; Haldane linearisation; Labelled partitioning process; Migration–recombination equation; Quasi-stationarity
Year: 2021 PMID: 33774735 PMCID: PMC8004498 DOI: 10.1007/s00285-021-01584-4
Source DB: PubMed Journal: J Math Biol ISSN: 0303-6812 Impact factor: 2.259