Literature DB >> 3377470

Improved sodium hydroxide digestion method without homogenization for extraction of gentamicin from renal tissue.

S A Brown1, K Sugimoto, G G Smith, F B Garry.   

Abstract

Recovery of gentamicin from renal cortical tissue (assayed by fluorescence polarization immunoassay) was highest (P less than 0.05) when using a sodium hydroxide (NaOH) digestion procedure without homogenization (90.0 +/- 5.4%), followed by homogenization with NaOH digestion (85.8 +/- 7.7%) and homogenization with trichloroacetic acid precipitation (84.4 +/- 3.3%). Simple homogenization recovered the least gentamicin (59.0 +/- 5.2%; P less than 0.05).

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3377470      PMCID： PMC172229          DOI： 10.1128/AAC.32.4.595

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  19 in total

1.  Single intravenous and multiple intramuscular dose pharmacokinetics and tissue residue profile of gentamicin in sheep.

Authors:  S A Brown; J E Riviere; G L Coppoc; E J Hinsman; W W Carlton; R R Steckel
Journal:  Am J Vet Res       Date:  1985-01       Impact factor: 1.156

2.  Improved procedure for extracting aminoglycosides from renal cortical tissue.

Authors:  R A Giuliano; G A Verpooten; D E Pollet; L Verbist; S L Scharpé; M E De Broe
Journal:  Antimicrob Agents Chemother       Date:  1984-06       Impact factor: 5.191

3.  Identification of the aminoglycoside binding site in rat renal brush border membranes.

Authors:  M Sastrasinh; T C Knauss; J M Weinberg; H D Humes
Journal:  J Pharmacol Exp Ther       Date:  1982-08       Impact factor: 4.030

Review 4.  [Aminoglycoside nephrotoxicity. I. Clinical aspects, morphology and tissue pharmacokinetics].

Authors:  J Fabre
Journal:  Nephrologie       Date:  1980

5.  Persistence of sisomicin and gentamicin in renal cortex and medulla compared with other organs and serum of rats.

Authors:  J Fabre; M Rudhardt; P Blanchard; C Regamey
Journal:  Kidney Int       Date:  1976-12       Impact factor: 10.612

6.  Relationship between rat renal accumulation of gentamicin, tobramycin, and netilmicin and their nephrotoxicities.

Authors:  M E Brier; P R Mayer; R A Brier; D Visscher; F C Luft; G R Aronoff
Journal:  Antimicrob Agents Chemother       Date:  1985-05       Impact factor: 5.191

7.  Interactions between renal brush border membranes and polyamines.

Authors:  B B Kirschbaum
Journal:  J Pharmacol Exp Ther       Date:  1984-05       Impact factor: 4.030

8.  Gentamicin tissue concentration in various avian species following recommended dosage therapy.

Authors:  M Bush; D Locke; L A Neal; J W Carpenter
Journal:  Am J Vet Res       Date:  1981-12       Impact factor: 1.156

9.  Non-linear accumulation of gentamicin in guinea-pig kidney.

Authors:  T Trnovec; S Bezek; Z Kállay; M Durisová; J Navarová
Journal:  J Antimicrob Chemother       Date:  1984-11       Impact factor: 5.790

10.  Triexponential disposition pharmacokinetics of gentamicin in rabbits.

Authors:  S M Huang; Y C Huang; W L Chiou
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1979-10
View more
  2 in total

1.  Poly-L-aspartic acid enhances and prolongs gentamicin-mediated suppression of the CFTR-G542X mutation in a cystic fibrosis mouse model.

Authors:  Ming Du; Kim M Keeling; Liming Fan; Xiaoli Liu; David M Bedwell
Journal:  J Biol Chem       Date:  2009-01-09       Impact factor: 5.157

2.  Effect of platelet activating factor antagonist treatment on gentamicin nephrotoxicity.

Authors:  A Rodriguez-Barbero; E Bosque; L Rivas-Cabaero; M Arévalo; J M López-Novoa
Journal:  Mediators Inflamm       Date:  1992       Impact factor: 4.711
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.