Literature DB >> 33771415

Growth Hormone Releasing Hormone in Endothelial Barrier Function.

Nektarios Barabutis1.   

Abstract

Growth hormone releasing hormone (GHRH) is the integral regulator of the growth hormone (GH)-insulin-like growth factor 1 (IGF-1) axis. It exerts mitogenic effects in a plethora of progressive cancers. Recent evidence suggests the emerging role of that 44-amino acid (aa) neuropeptide in lung endothelial barrier function (EBF), which will be discussed herein.
Copyright © 2021 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  acute lung injury; acute respiratory distress syndrome; sepsis

Mesh：

Substances：

Year:  2021        PMID： 33771415      PMCID： PMC8102361          DOI： 10.1016/j.tem.2021.03.001

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   10.586


  15 in total

1.  Impact of Axis of GHRH and GHRH Receptor on Cell Viability and Apoptosis of the Placental Choriocarcinoma Cell Line.

Authors:  A-X Liu; D Zhang; Y-M Zhu; H-J Gao; J-Y Jiang; X-L Hu; P-P Lv; P C K Leung; H-F Huang
Journal:  Curr Mol Med       Date:  2016       Impact factor: 2.222

Review 2.  Role of GTPases in control of microvascular permeability.

Authors:  Volker Spindler; Nicolas Schlegel; Jens Waschke
Journal:  Cardiovasc Res       Date:  2010-03-17       Impact factor: 10.787

3.  Inhibition of tumor growth by agonists of growth hormone-releasing hormone.

Authors:  Hippokratis Kiaris; Ioulia Chatzistamou
Journal:  Proc Natl Acad Sci U S A       Date:  2018-11-07       Impact factor: 11.205

4.  GHRH antagonists support lung endothelial barrier function.

Authors:  Mohammad A Uddin; Mohammad S Akhter; Sitanshu S Singh; Khadeja-Tul Kubra; Andrew V Schally; Seetharama Jois; Nektarios Barabutis
Journal:  Tissue Barriers       Date:  2019-10-03

Review 5.  Actions and Potential Therapeutic Applications of Growth Hormone-Releasing Hormone Agonists.

Authors:  Andrew V Schally; Xianyang Zhang; Renzhi Cai; Joshua M Hare; Riccarda Granata; Manuela Bartoli
Journal:  Endocrinology       Date:  2019-07-01       Impact factor: 4.736

6.  Effect of growth hormone-releasing hormone (GHRH) and GHRH antagonist (MZ-4-71) on interferon-gamma secretion from human peripheral blood mononuclear cells in vitro.

Authors:  A Siejka; H Ławnicka; J Komorowski; T Stepień; R Krupiński; H Stepień
Journal:  Neuropeptides       Date:  2004-02       Impact factor: 3.286

Review 7.  Acute respiratory distress syndrome.

Authors:  Michael A Matthay; Rachel L Zemans; Guy A Zimmerman; Yaseen M Arabi; Jeremy R Beitler; Alain Mercat; Margaret Herridge; Adrienne G Randolph; Carolyn S Calfee
Journal:  Nat Rev Dis Primers       Date:  2019-03-14       Impact factor: 52.329

8.  Growth Hormone-Releasing Hormone Receptor Antagonist Modulates Lung Inflammation and Fibrosis due to Bleomycin.

Authors:  Chongxu Zhang; Renzhi Cai; Aaron Lazerson; Gaetan Delcroix; Medhi Wangpaichitr; Mehdi Mirsaeidi; Anthony J Griswold; Andrew V Schally; Robert M Jackson
Journal:  Lung       Date:  2019-08-07       Impact factor: 2.584

9.  Involvement of the unfolded protein response in the protective effects of growth hormone releasing hormone antagonists in the lungs.

Authors:  Mohammad S Akhter; Mohammad A Uddin; Andrew V Schally; Khadeja-Tul Kubra; Nektarios Barabutis
Journal:  J Cell Commun Signal       Date:  2020-11-13       Impact factor: 5.782
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  9 in total

1.  P53 mediates the protective effects of metformin in inflamed lung endothelial cells.

Authors:  Khadeja-Tul Kubra; Mohammad A Uddin; Mohammad S Akhter; Antoinette J Leo; Agnieszka Siejka; Nektarios Barabutis
Journal:  Int Immunopharmacol       Date:  2021-11-15       Impact factor: 4.932

2.  Unfolded protein response in endothelial injury.

Authors:  Nektarios Barabutis
Journal:  Cell Cycle       Date:  2022-05-26       Impact factor: 5.173

3.  Protective effects of GHRH antagonists against hydrogen peroxide-induced lung endothelial barrier disruption.

Authors:  Mohammad S Akhter; Khadeja-Tul Kubra; Nektarios Barabutis
Journal:  Endocrine       Date:  2022-10-20       Impact factor: 3.925

4.  Tunicamycin Protects against LPS-Induced Lung Injury.

Authors:  Khadeja-Tul Kubra; Mohammad A Uddin; Nektarios Barabutis
Journal:  Pharmaceuticals (Basel)       Date:  2022-01-24

5.  Mechanosensitive Channel PIEZO1 Senses Shear Force to Induce KLF2/4 Expression via CaMKII/MEKK3/ERK5 Axis in Endothelial Cells.

Authors:  Qi Zheng; Yonggang Zou; Peng Teng; Zhenghua Chen; Yuefeng Wu; Xiaoyi Dai; Xiya Li; Zonghao Hu; Shengjun Wu; Yanhua Xu; Weiguo Zou; Hai Song; Liang Ma
Journal:  Cells       Date:  2022-07-13       Impact factor: 7.666

6.  Therapeutic Effects of Retinoic Acid in Lipopolysaccharide-Induced Cardiac Dysfunction: Network Pharmacology and Experimental Validation.

Authors:  Xi Wang; Chang Kong; Pan Liu; Baofeng Zhou; Wujun Geng; Hongli Tang
Journal:  J Inflamm Res       Date:  2022-08-30

7.  Elucidation of the Molecular Pathways Involved in the Protective Effects of AUY-922 in LPS-Induced Inflammation in Mouse Lungs.

Authors:  Mohammad S Akhter; Mohammad A Uddin; Khadeja-Tul Kubra; Nektarios Barabutis
Journal:  Pharmaceuticals (Basel)       Date:  2021-05-29

8.  Induction of the NEK family of kinases in the lungs of mice subjected to cecal ligation and puncture model of sepsis.

Authors:  Mohammad A Uddin; Mohammad S Akhter; Khadeja-Tul Kubra; Nektarios Barabutis
Journal:  Tissue Barriers       Date:  2021-06-20

9.  Suppression of reactive oxygen species in endothelial cells by an antagonist of growth hormone-releasing hormone.

Authors:  Mohammad S Akhter; Nektarios Barabutis
Journal:  J Biochem Mol Toxicol       Date:  2021-08-08       Impact factor: 3.568
  9 in total

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