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Literature DB >> 35617133

Unfolded protein response in endothelial injury.

Abstract

Endothelial barrier dysfunction is associated with sepsis and lung injury, both direct and indirect. We discuss the involvement of unfolded protein response in the protective effects of heat shock protein 90 inhibitors and growth hormone releasing hormone antagonists in the vascular barrier, to reveal new possibilities in acute respiratory distress syndrome treatment.

Entities: Chemical

Keywords: Growth hormone; heat shock proteins; lung injury; sepsis

Mesh：

Year: 2022 PMID： 35617133 PMCID： PMC9467570 DOI： 10.1080/15384101.2022.2082024

Source DB: PubMed Journal: Cell Cycle ISSN： 1551-4005 Impact factor: 5.173

53 in total

1. Kifunensine compromises lung endothelial barrier function.

Authors: Mohammad Shohel Akhter; Khadeja-Tul Kubra; Mohammad A Uddin; Nektarios Barabutis
Journal: Microvasc Res Date: 2020-07-28 Impact factor: 3.514

Review 2. Actions and Potential Therapeutic Applications of Growth Hormone-Releasing Hormone Agonists.

Authors: Andrew V Schally; Xianyang Zhang; Renzhi Cai; Joshua M Hare; Riccarda Granata; Manuela Bartoli
Journal: Endocrinology Date: 2019-07-01 Impact factor: 4.736

3. A glimpse at growth hormone-releasing hormone cosmos.

Authors: Nektarios Barabutis
Journal: Clin Exp Pharmacol Physiol Date: 2020-04-25 Impact factor: 2.557

4. Synthesis and biological activities of highly potent antagonists of growth hormone-releasing hormone.

Authors: M Zarandi; J E Horvath; G Halmos; J Pinski; A Nagy; K Groot; Z Rekasi; A V Schally
Journal: Proc Natl Acad Sci U S A Date: 1994-12-06 Impact factor: 11.205

5. Regulation of lung endothelial permeability by NEK kinases.

Authors: Nektarios Barabutis
Journal: IUBMB Life Date: 2020-02-11 Impact factor: 3.885

6. Wild-type p53 enhances endothelial barrier function by mediating RAC1 signalling and RhoA inhibition.

Authors: Nektarios Barabutis; Christiana Dimitropoulou; Betsy Gregory; John D Catravas
Journal: J Cell Mol Med Date: 2018-01-24 Impact factor: 5.310

Review 7. P53, GHRH, inflammation and cancer.

Authors: Nektarios Barabutis; Andrew V Schally; Agnieszka Siejka
Journal: EBioMedicine Date: 2018-10-19 Impact factor: 8.143

8. Induction of the NEK family of kinases in the lungs of mice subjected to cecal ligation and puncture model of sepsis.

Authors: Mohammad A Uddin; Mohammad S Akhter; Khadeja-Tul Kubra; Nektarios Barabutis
Journal: Tissue Barriers Date: 2021-06-20

9. Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis.

Authors: Erik A Blackwood; Khalid Azizi; Donna J Thuerauf; Ryan J Paxman; Lars Plate; Jeffery W Kelly; R Luke Wiseman; Christopher C Glembotski
Journal: Nat Commun Date: 2019-01-14 Impact factor: 17.694

10. Insights on supporting the aging brain microvascular endothelium.

Authors: Nektarios Barabutis
Journal: Aging Brain Date: 2021-02-22

1 in total

1. Protective effects of GHRH antagonists against hydrogen peroxide-induced lung endothelial barrier disruption.

Authors: Mohammad S Akhter; Khadeja-Tul Kubra; Nektarios Barabutis
Journal: Endocrine Date: 2022-10-20 Impact factor: 3.925

1 in total