D M L Saunte1,2,3, M Pereiro-Ferreirós1,4, C Rodríguez-Cerdeira1,5, A Y Sergeev1,6, M Arabatzis1,7, A Prohić1,8, B M Piraccini1,9, P Lecerf1,10, P Nenoff1,11, L P Kotrekhova12, P P Bosshard13, V Padovese14, J C Szepietowski1,15, B Sigurgeirsson1,16, R J Nowicki1,17, P Schmid-Grendelmeier1,18, R J Hay1,19. 1. European Academy of Dermatology and Venereology TASK force on Mycology. 2. Department of Dermatology, Zealand University Hospital, Roskilde, Denmark. 3. Department of Clinical Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. 4. Dermatología, Faculty of Medicine, University of Santiago de Compostela, A Coruña, Spain. 5. Department of Dermatology, Meixoeiro Hospital and University of Vigo, Vigo, Spain. 6. Department of Clinical Immunology, Sechenov University, Moscow, Russia. 7. Department of Dermatology, Medical School, Aristotle University, Thessaloniki, Greece. 8. Department of Dermatovenereology, University Sarajevo School of Science and Technology, Sarajevo Medical School, Sarajevo, Bosnia and Herzegovina. 9. Dermatology -IRCCS Policlinico di Sant'Orsola Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum University of Bologna, Bologna, Italy. 10. Department of Dermatology, University Hospital Brugmann & Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium. 11. Laboratory for Medical Microbiology, Mölbis, Germany. 12. Department of Dermatovenereology, North Western State Medical University, Saint Petersburg, Russia. 13. Department of Dermatology, University Hospital Zurich and Medical Faculty, University of Zurich, Zurich, Switzerland. 14. Department of Dermatology and Venereology, Genitourinary Clinic, Mater Dei Hospital, Msida, Malta. 15. Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland. 16. Department of Dermatology, Faculty of Medicine, University of Iceland, Reykjavik, Iceland. 17. Department of Dermatology, Venereology & Allergology, Medical University of Gdansk, Gdansk, Poland. 18. Allergy Unit, Department of Dermatology, University Hospital Zurich and Medical Faculty, University of Zurich, Zurich, Switzerland. 19. St John's Institute of Dermatology, Kings College London, London, UK.
Abstract
BACKGROUND: Dermatophytosis is a world-wide distributed common infection. Antifungal drug resistance in dermatophytosis used to be rare, but unfortunately the current Indian epidemic of atypical widespread recalcitrant and terbinafine-resistant dermatophytosis is spreading and has sporadically been reported in Europe. OBJECTIVES: To explore the occurrence of clinical and mycological proven antifungal drug resistance in dermatophytes in Europe. METHODS: A standardized questionnaire was distributed through the EADV Task Force of Mycology network to dermatologists in Europe. RESULTS: Representatives from 20 countries completed the questionnaires of which 17 (85 %) had observed clinical and/or mycological confirmed antifungal resistance, two countries published cases of antifungal resistance and one country had no known cases. CONCLUSIONS: This pilot study confirms that both clinical and mycological antifungal resistance exist in Europe.
BACKGROUND:Dermatophytosis is a world-wide distributed common infection. Antifungal drug resistance in dermatophytosis used to be rare, but unfortunately the current Indian epidemic of atypical widespread recalcitrant and terbinafine-resistant dermatophytosis is spreading and has sporadically been reported in Europe. OBJECTIVES: To explore the occurrence of clinical and mycological proven antifungal drug resistance in dermatophytes in Europe. METHODS: A standardized questionnaire was distributed through the EADV Task Force of Mycology network to dermatologists in Europe. RESULTS: Representatives from 20 countries completed the questionnaires of which 17 (85 %) had observed clinical and/or mycological confirmed antifungal resistance, two countries published cases of antifungal resistance and one country had no known cases. CONCLUSIONS: This pilot study confirms that both clinical and mycological antifungal resistance exist in Europe.
Authors: Thomas R Rogers; Paul E Verweij; Mariana Castanheira; Eric Dannaoui; P Lewis White; Maiken Cavling Arendrup Journal: J Antimicrob Chemother Date: 2022-07-28 Impact factor: 5.758