Literature DB >> 34633845

In Vitro Antifungal Combination of Terbinafine with Itraconazole against Isolates of Trichophyton Species.

Anne-Laure Bidaud1, Patrick Schwarz2,3, Anuradha Chowdhary4, Eric Dannaoui1,5.   

Abstract

Terbinafine is used as the first-line therapy for dermatophytosis, but the incidence of terbinafine resistance is increasing. A combination of terbinafine with itraconazole was tested using the checkerboard method based on the EUCAST methodology for antifungal susceptibility testing against 9 terbinafine-susceptible and 7 terbinafine-resistant clinical isolates of Trichophyton spp. from India. Synergistic interactions were observed for 4/9 of the susceptible isolates, with fractional inhibitory concentration index (FICI) values of 0.3125 to 0.5, and for 4/7 of the resistant isolates, with FICI values of 0.032 to 0.3125.

Entities:  

Keywords:  EUCAST; Trichophyton; antifungal combination; dermatophytes; itraconazole; terbinafine

Mesh：

Substances：

Year:  2021        PMID： 34633845      PMCID： PMC8765265          DOI： 10.1128/AAC.01449-21

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.938


  32 in total

1.  Successful control of disseminated Scedosporium prolificans infection with a combination of voriconazole and terbinafine.

Authors:  B P Howden; M A Slavin; A P Schwarer; A M Mijch
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2003-02-14       Impact factor: 3.267

2.  'End of the road for terbinafine' in dermatophytosis: Is it a valid conclusion?

Authors:  Rajsmita Bhattacharjee; Sunil Dogra
Journal:  Indian J Dermatol Venereol Leprol       Date:  2018 Nov-Dec       Impact factor: 2.545

3.  High terbinafine resistance in Trichophyton interdigitale isolates in Delhi, India harbouring mutations in the squalene epoxidase gene.

Authors:  Ashutosh Singh; Aradhana Masih; Ananta Khurana; Pradeep Kumar Singh; Meenakshi Gupta; Ferry Hagen; Jacques F Meis; Anuradha Chowdhary
Journal:  Mycoses       Date:  2018-04-27       Impact factor: 4.377

4.  In vitro antidermatophytic synergism of double and triple combination of clioquinol with ciclopirox and terbinafine.

Authors:  Bárbara da Costa; Bruna Pippi; Taís Fernanda Andrzejewski Kaminski; Saulo F Andrade; Alexandre M Fuentefria
Journal:  Mycoses       Date:  2020-07-01       Impact factor: 4.377

Review 5.  Antifungal resistance in dermatophytes: Recent trends and therapeutic implications.

Authors:  Ananta Khurana; Kabir Sardana; Anuradha Chowdhary
Journal:  Fungal Genet Biol       Date:  2019-07-19       Impact factor: 3.495

6.  In vitro susceptibility of dermatomycoses agents to six antifungal drugs and evaluation by fractional inhibitory concentration index of combined effects of amorolfine and itraconazole in dermatophytes.

Authors:  Takashi Tamura; Miwa Asahara; Mikachi Yamamoto; Mariko Yamaura; Mitsuru Matsumura; Kazuo Goto; Ali Rezaei-Matehkolaei; Hossein Mirhendi; Miho Makimura; Koichi Makimura
Journal:  Microbiol Immunol       Date:  2014-01       Impact factor: 1.955

7.  Correlation of In Vitro Susceptibility Based on MICs and Squalene Epoxidase Mutations with Clinical Response to Terbinafine in Patients with Tinea Corporis/Cruris.

Authors:  Ananta Khurana; Aradhana Masih; Anuradha Chowdhary; Kabir Sardana; Sagar Borker; Aastha Gupta; R K Gautam; P K Sharma; Dhruv Jain
Journal:  Antimicrob Agents Chemother       Date:  2018-11-26       Impact factor: 5.191

Review 8.  How to: perform antifungal susceptibility testing of microconidia-forming dermatophytes following the new reference EUCAST method E.Def 11.0, exemplified by Trichophyton.

Authors:  Maiken C Arendrup; Gunnar Kahlmeter; Jesus Guinea; Joseph Meletiadis
Journal:  Clin Microbiol Infect       Date:  2020-09-08       Impact factor: 8.067

9.  Voriconazole plus terbinafine combination antifungal therapy for invasive Lomentospora prolificans infections: analysis of 41 patients from the FungiScope® registry 2008-2019.

Authors:  J D Jenks; D Seidel; O A Cornely; S Chen; S van Hal; C Kauffman; M H Miceli; M Heinemann; M Christner; A Jover Sáenz; A Burchardt; B Kemmerling; R Herbrecht; J Steinmann; S Shoham; S Gräber; L Pagano; D Deeren; S Aslam; R Taplitz; S G Revankar; J Baddley; S R Mehta; S Reed; M A Slavin; M Hoenigl
Journal:  Clin Microbiol Infect       Date:  2020-01-20       Impact factor: 8.067

10.  Emerging Terbinafine Resistance in Trichophyton: Clinical Characteristics, Squalene Epoxidase Gene Mutations, and a Reliable EUCAST Method for Detection.

Authors:  Ditte M L Saunte; Rasmus K Hare; Karin M Jørgensen; René Jørgensen; Mette Deleuran; Claus O Zachariae; Simon F Thomsen; Lars Bjørnskov-Halkier; Kristian Kofoed; Maiken C Arendrup
Journal:  Antimicrob Agents Chemother       Date:  2019-09-23       Impact factor: 5.191
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  3 in total

Review 1.  Augmenting Azoles with Drug Synergy to Expand the Antifungal Toolbox.

Authors:  Aidan Kane; Dee A Carter
Journal:  Pharmaceuticals (Basel)       Date:  2022-04-14

2.  In Vitro Study of the Interaction of Gentamicin with Ceftriaxone and Azithromycin against Neisseria gonorrhoeae Using Agar Dilution Method.

Authors:  Wenqi Xu; Qian Zhou; Jingwei Liu; Yan Zhang; Xiaoyu Zhu; Bangyong Zhu; Yueping Yin
Journal:  Antibiotics (Basel)       Date:  2022-08-10

3.  The emergence and worldwide spread of the species Trichophyton indotineae causing difficult-to-treat dermatophytosis: A new challenge in the management of dermatophytosis.

Authors:  Anuradha Chowdhary; Ashutosh Singh; Amtoj Kaur; Ananta Khurana
Journal:  PLoS Pathog       Date:  2022-09-29       Impact factor: 7.464
  3 in total

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