| Literature DB >> 33765306 |
Denise Brennan1, Colm O'Morain1, Deirdre McNamara1,2, Sinéad M Smith3.
Abstract
Antimicrobial susceptibility testing (AST) for H. pylori is essential to accurately assess the prevalence of antibiotic resistance in each population. Antibiotic resistance rates form the basis of local guidelines for H. pylori treatment and AST may also be used as a personalized medicine approach to tailor therapy. This chapter provides an update on global antibiotic resistance rates and describes molecular mechanisms that confer H. pylori antibiotic resistance. An overview on the advantages and limitations of molecular AST using both invasive and noninvasive approaches is also provided.Entities:
Keywords: Antibiotic; Antimicrobial susceptibility testing; Clarithromycin; DNA mutation; Helicobacter pylori; Levofloxacin; Molecular test; PCR
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Year: 2021 PMID： 33765306 DOI： 10.1007/978-1-0716-1302-3_4
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745