Saad Ghafoor1, Kimberly Fan2, Sarah Williams1, Amanda Brown1, Sarah Bowman1, Kenneth L Pettit3, Shilpa Gorantla3, Rebecca Quillivan3, Sarah Schwartzberg4, Amanda Curry4, Lucy Parkhurst4, Marshay James1, Jennifer Smith5, Kristin Canavera6, Andrew Elliott7, Michael Frett8, Deni Trone9, Jacqueline Butrum-Sullivan10, Cynthia Barger11, Mary Lorino11, Jennifer Mazur12, Mandi Dodson12, Morgan Melancon12, Leigh Anne Hall11, Jason Rains10, Yvonne Avent1, Jonathan Burlison13, Fang Wang14, Haitao Pan14, Mary Anne Lenk15, R Ray Morrison1, Sapna R Kudchadkar16. 1. Division of Critical Care Medicine, Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN, United States. 2. Department of Pediatric Critical Care, University of Tennessee Health Science Center, Memphis, TN, United States. 3. Office of Quality and Patient Care, St. Jude Children's Research Hospital, Memphis, TN, United States. 4. Department of Rehabilitation Services, St. Jude Children's Research Hospital, Memphis, TN, United States. 5. Department of Child Life, St. Jude Children's Research Hospital, Memphis, TN, United States. 6. Department of Psychology, St. Jude Children's Research Hospital, Memphis, TN, United States. 7. Division of Psychiatry, Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN, United States. 8. Division of Anesthesiology, Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN, United States. 9. Department of Pharmaceutical Services, St. Jude Children's Research Hospital, Memphis, TN, United States. 10. Department Critical Care/Pulmonary Medicine-Respiratory Therapy, St. Jude Children's Research Hospital, Memphis, TN, United States. 11. Department of Inpatient Units-Nursing, St. Jude Children's Research Hospital, Memphis, TN, United States. 12. Department of Nursing Administration- Nursing Education, St. Jude Children's Research Hospital, Memphis, TN, United States. 13. Department of Pharmaceutical Sciences- Patient Safety, St. Jude Children's Research Hospital, Memphis, TN, United States. 14. Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, United States. 15. Department of Quality Improvement Education and Training, Cincinnati Children's Hospital- James M. Anderson Center for Health Systems Excellence, Cincinnati, OH, United States. 16. Departments of Anesthesiology and Critical Care Medicine, Pediatrics and Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Abstract
INTRODUCTION: Children with underlying oncologic and hematologic diseases who require critical care services have unique risk factors for developing functional impairments from pediatric post-intensive care syndrome (PICS-p). Early mobilization and rehabilitation programs offer a promising approach for mitigating the effects of PICS-p in oncology patients but have not yet been studied in this high-risk population. METHODS: We describe the development and feasibility of implementing an early mobility quality improvement initiative in a dedicated pediatric onco-critical care unit. Our primary outcomes include the percentage of patients with consults for rehabilitation services within 72 h of admission, the percentage of patients who are mobilized within 72 h of admission, and the percentage of patients with a positive delirium screen after 48 h of admission. RESULTS: Between January 2019 and June 2020, we significantly increased the proportion of patients with consults ordered for rehabilitation services within 72 h of admission from 25 to 56% (p<0.001), increased the percentage of patients who were mobilized within 72 h of admission to the intensive care unit from 21 to 30% (p=0.02), and observed a decrease in patients with positive delirium screens from 43 to 37% (p=0.46). The early mobility initiative was not associated with an increase in unplanned extubations, unintentional removal of central venous catheters, or injury to patient or staff. CONCLUSIONS: Our experience supports the safety and feasibility of early mobility initiatives in pediatric onco-critical care. Additional evaluation is needed to determine the effects of early mobilization on patient outcomes.
INTRODUCTION: Children with underlying oncologic and hematologic diseases who require critical care services have unique risk factors for developing functional impairments from pediatric post-intensive care syndrome (PICS-p). Early mobilization and rehabilitation programs offer a promising approach for mitigating the effects of PICS-p in oncology patients but have not yet been studied in this high-risk population. METHODS: We describe the development and feasibility of implementing an early mobility quality improvement initiative in a dedicated pediatric onco-critical care unit. Our primary outcomes include the percentage of patients with consults for rehabilitation services within 72 h of admission, the percentage of patients who are mobilized within 72 h of admission, and the percentage of patients with a positive delirium screen after 48 h of admission. RESULTS: Between January 2019 and June 2020, we significantly increased the proportion of patients with consults ordered for rehabilitation services within 72 h of admission from 25 to 56% (p<0.001), increased the percentage of patients who were mobilized within 72 h of admission to the intensive care unit from 21 to 30% (p=0.02), and observed a decrease in patients with positive delirium screens from 43 to 37% (p=0.46). The early mobility initiative was not associated with an increase in unplanned extubations, unintentional removal of central venous catheters, or injury to patient or staff. CONCLUSIONS: Our experience supports the safety and feasibility of early mobility initiatives in pediatric onco-critical care. Additional evaluation is needed to determine the effects of early mobilization on patient outcomes.
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