Literature DB >> 3375507

Chemical scoring by a rapid screening of hazard (RASH) method.

T D Jones1, P J Walsh, A P Watson, B A Owen, L W Barnthouse, D A Sanders.   

Abstract

A rapid screening of hazard method (RASH) is presented for deriving relative potency estimates for hazardous substances. The method utilizes data from any available toxicological database such as the Registry of Toxic Effects of Chemical Substances (RTECS) or EPA's GENE-TOX database on genetic activity profiles. The method has been applied to derive relative potency values and permissible environmental concentrations for 278 chemicals. The derived values have been compared with recommendations of expert committees where possible, and substantial agreement is found.

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Year:  1988        PMID: 3375507     DOI: 10.1111/j.1539-6924.1988.tb01157.x

Source DB:  PubMed          Journal:  Risk Anal        ISSN: 0272-4332            Impact factor:   4.000


  4 in total

1.  Protection of human health from mixtures of radionuclides and chemical in drinking water.

Authors:  T D Jones; B A Owen; J R Trabalka
Journal:  Arch Environ Contam Toxicol       Date:  1991-01       Impact factor: 2.804

2.  Ranking of carcinogenic potency using a relative potency approach.

Authors:  L R Glass; C E Easterly; T D Jones; P J Walsh
Journal:  Arch Environ Contam Toxicol       Date:  1991-08       Impact factor: 2.804

3.  A RASH analysis of National Toxicology Program data: predictions for 30 compounds to be tested in rodent carcinogenesis experiments.

Authors:  T D Jones; C E Easterly
Journal:  Environ Health Perspect       Date:  1996-10       Impact factor: 9.031

4.  Toxicological potency of 2,3,7,8-tetrachlorodibenzo-p-dioxin relative to 100 other compounds: a relative potency analysis of in vitro and in vivo test data.

Authors:  T D Jones
Journal:  Arch Environ Contam Toxicol       Date:  1995-07       Impact factor: 2.804

  4 in total

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