Literature DB >> 33754124

COVID-19 pandemic: the implications of the natural history, challenges of diagnosis and management for care in sub-Saharan Africa.

Lawrence Omo-Aghoja1, Emuesiri Goodies Moke1, Kenneth Kelechi Anachuna1, Adrian Itivere Omogbiya1, Emuesiri Kohworho Umukoro1, Pere-Ebi Yabrade Toloyai1, Tarela Melish Elias Daubry1, Anthony Taghogho Eduviere1.   

Abstract

BACKGROUND: Coronavirus disease (COVID-19) is a severe acute respiratory infection which has afflicted virtually almost all nations of the earth. It is highly transmissible and represents one of the most serious pandemics in recent times, with the capacity to overwhelm any healthcare system and cause morbidity and fatality. MAIN CONTENT: The diagnosis of this disease is daunting and challenging as it is dependent on emerging clinical symptomatology that continues to increase and change very rapidly. The definitive test is the very expensive and scarce polymerase chain reaction (PCR) viral identification technique. The management has remained largely supportive and empirical, as there are no officially approved therapeutic agents, vaccines or antiviral medications for the management of the disease. Severe cases often require intensive care facilities and personnel. Yet there is paucity of facilities including the personnel required for diagnosis and treatment of COVID-19 in sub-Saharan Africa (SSA). It is against this backdrop that a review of key published reports on the pandemic in SSA and globally is made, as understanding the natural history of a disease and the documented responses to diagnosis and management is usually a key public health strategy for designing and improving as appropriate, relevant interventions. Lead findings were that responses by most nations of SSA were adhoc, paucity of public health awareness strategies and absence of legislations that would help enforce preventive measures, as well as limited facilities (including personal protective equipment) and institutional capacities to deliver needed interventions.
CONCLUSION: COVID-19 is real and has overwhelmed global health care system especially low-income countries of the sub-Sahara such as Nigeria. Suggestions for improvement of healthcare policies and programs to contain the current pandemic and to respond more optimally in case of future pandemics are made herein.
© The Author(s) 2021.

Entities:  

Keywords:  COVID-19; Management; Natural history; Nigeria; Respiratory infection

Year:  2021        PMID: 33754124      PMCID: PMC7968562          DOI: 10.1186/s43088-021-00106-x

Source DB:  PubMed          Journal:  Beni Suef Univ J Basic Appl Sci        ISSN: 2314-8535


  71 in total

1.  Evaluation of swabs, transport media, and specimen transport conditions for optimal detection of viruses by PCR.

Authors:  Julian Druce; Katherine Garcia; Thomas Tran; Georgina Papadakis; Chris Birch
Journal:  J Clin Microbiol       Date:  2012-01-11       Impact factor: 5.948

2.  A Framework for Rationing Ventilators and Critical Care Beds During the COVID-19 Pandemic.

Authors:  Douglas B White; Bernard Lo
Journal:  JAMA       Date:  2020-05-12       Impact factor: 56.272

Review 3.  Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus.

Authors:  Susan R Weiss; Sonia Navas-Martin
Journal:  Microbiol Mol Biol Rev       Date:  2005-12       Impact factor: 11.056

4.  Point-of-Care Lung Ultrasound findings in novel coronavirus disease-19 pnemoniae: a case report and potential applications during COVID-19 outbreak.

Authors:  D Buonsenso; A Piano; F Raffaelli; N Bonadia; K de Gaetano Donati; F Franceschi
Journal:  Eur Rev Med Pharmacol Sci       Date:  2020-03       Impact factor: 3.507

5.  Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.

Authors:  Xiaobo Yang; Yuan Yu; Jiqian Xu; Huaqing Shu; Jia'an Xia; Hong Liu; Yongran Wu; Lu Zhang; Zhui Yu; Minghao Fang; Ting Yu; Yaxin Wang; Shangwen Pan; Xiaojing Zou; Shiying Yuan; You Shang
Journal:  Lancet Respir Med       Date:  2020-02-24       Impact factor: 30.700

6.  Is Coronavirus Disease 2019 (COVID-19) seen less in countries more exposed to Malaria?

Authors:  Gokhan Sargin; Sare İlknur Yavaşoğlu; Irfan Yavasoglu
Journal:  Med Hypotheses       Date:  2020-04-22       Impact factor: 1.538

Review 7.  The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients.

Authors:  Yan-Chao Li; Wan-Zhu Bai; Tsutomu Hashikawa
Journal:  J Med Virol       Date:  2020-03-11       Impact factor: 2.327

8.  Correlation analysis between disease severity and inflammation-related parameters in patients with COVID-19: a retrospective study.

Authors:  Jing Gong; Hui Dong; Qing-Song Xia; Zhao-Yi Huang; Ding-Kun Wang; Yan Zhao; Wen-Hua Liu; Sheng-Hao Tu; Ming-Min Zhang; Qi Wang; Fu-Er Lu
Journal:  BMC Infect Dis       Date:  2020-12-21       Impact factor: 3.090

9.  Effects of Response to 2014-2015 Ebola Outbreak on Deaths from Malaria, HIV/AIDS, and Tuberculosis, West Africa.

Authors:  Alyssa S Parpia; Martial L Ndeffo-Mbah; Natasha S Wenzel; Alison P Galvani
Journal:  Emerg Infect Dis       Date:  2016-03       Impact factor: 6.883

10.  Proposal for International Standardization of the Use of Lung Ultrasound for Patients With COVID-19: A Simple, Quantitative, Reproducible Method.

Authors:  Gino Soldati; Andrea Smargiassi; Riccardo Inchingolo; Danilo Buonsenso; Tiziano Perrone; Domenica Federica Briganti; Stefano Perlini; Elena Torri; Alberto Mariani; Elisa Eleonora Mossolani; Francesco Tursi; Federico Mento; Libertario Demi
Journal:  J Ultrasound Med       Date:  2020-04-13       Impact factor: 2.754

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