Positive Affect: Nature and brain bases of liking and wanting.

The positive affect of rewards is an important contributor to well-being. Reward involves components of pleasure 'liking', motivation 'wanting', and learning. 'Liking' refers to the hedonic impact of positive events, with underlying mechanisms that include hedonic hotspots in limbic brain structures that amplify 'liking' reactions. 'Wanting' refers to incentive salience, a motivational process that makes reward cues attractive and able to trigger craving for their reward, mediated by larger dopamine-related mesocorticolimbic networks. Under normal conditions, 'liking' and 'wanting' cohere. However, 'liking' and 'wanting' can be dissociated by alterations in neural signaling, either induced in animal neuroscience laboratories or arising spontaneously in addictions and other affective disorders, which can be detrimental to positive well-being.