Abass Inusah1,2, Elvis Quansah3, Kwabena Fosu2, Isaac Dadzie1. 1. Department of Medical Laboratory Science, School of Allied Health Sciences, University of Cape Coast, Cape Coast, Ghana. 2. Microbiology Department, Bolgatanga Regional Hospital, Bolgatanga, Ghana. 3. Department of Microbiology and Immunology, School of Medical Science, University of Cape Coast, Cape Coast, Ghana.
Abstract
BACKGROUND: Regardless of the global concerted effort to control the development and spread of antimicrobial resistance, increasing cases are continually documented at many medical centres. This situation is reinforced by inadequate information on the trend of resistance resulting from lack of regular antimicrobial resistance surveillance. The present study sought to detect the number of multidrug-resistant (MDR), extended drug-resistant (XDR), and pandrug-resistant (PDR) bacterial isolates at a health facility in Ghana from January 2018 to July 2020. METHOD: A total of 800 data on antimicrobial testing results were extracted from the records of the health facility. The extracted data were explored for the detection of MDR, XDR, and PDR. The study further determined the use of antibiotics using the multiple-drug resistance index (MDRI). RESULTS: Except for Staphylococcus and Neisseria spp., all bacterial isolates showed extremely high (100%) proportion of MDR. Although only Staphylococcus spp. (38 (4.8%)) was observed to be XDR, the rest of the bacteria showed the potential to attain the status of XDR or PDR. MDRI indicated high use of antibiotics in the health facility. CONCLUSION: The high antimicrobial resistance observed by the study underscores the need for prompt and effective antibiotic resistance control strategies.
BACKGROUND: Regardless of the global concerted effort to control the development and spread of antimicrobial resistance, increasing cases are continually documented at many medical centres. This situation is reinforced by inadequate information on the trend of resistance resulting from lack of regular antimicrobial resistance surveillance. The present study sought to detect the number of multidrug-resistant (MDR), extended drug-resistant (XDR), and pandrug-resistant (PDR) bacterial isolates at a health facility in Ghana from January 2018 to July 2020. METHOD: A total of 800 data on antimicrobial testing results were extracted from the records of the health facility. The extracted data were explored for the detection of MDR, XDR, and PDR. The study further determined the use of antibiotics using the multiple-drug resistance index (MDRI). RESULTS: Except for Staphylococcus and Neisseria spp., all bacterial isolates showed extremely high (100%) proportion of MDR. Although only Staphylococcus spp. (38 (4.8%)) was observed to be XDR, the rest of the bacteria showed the potential to attain the status of XDR or PDR. MDRI indicated high use of antibiotics in the health facility. CONCLUSION: The high antimicrobial resistance observed by the study underscores the need for prompt and effective antibiotic resistance control strategies.
Authors: Nicholas Agyepong; Usha Govinden; Alex Owusu-Ofori; Sabiha Yusuf Essack Journal: Antimicrob Resist Infect Control Date: 2018-03-09 Impact factor: 4.887
Authors: Nana Ama Amissah; Andrew H Buultjens; Anthony Ablordey; Lieke van Dam; Ampomah Opoku-Ware; Sarah L Baines; Dieter Bulach; Caitlin S Tetteh; Isaac Prah; Tjip S van der Werf; Alexander W Friedrich; Torsten Seemann; Jan Maarten van Dijl; Ymkje Stienstra; Timothy P Stinear; John W Rossen Journal: Front Microbiol Date: 2017-10-06 Impact factor: 5.640