| Literature DB >> 3373534 |
J P Robinson1, M F Schmid, D G Morgan, W Chiu.
Abstract
Two-dimensional crystalline arrays of native tetanus toxin have been formed at the interface between a solution of the toxin and a phospholipid monolayer containing a ganglioside. Electron crystallographic analysis has been used to study these periodic arrays. The arrays obey the symmetry of plane group p12(1), with a = 126 A and b = 84 A, and a thickness of 90 A (1 A = 0.1 nm). The three-dimensional structure of tetanus toxin in negative stain is reconstructed to a nominal resolution of 14 A from multiple tilt images. The molecule presents an asymmetric three-lobed structure and could interact with the monolayer in two possible orientations.Entities:
Mesh：
Substances：
Year: 1988 PMID： 3373534 DOI： 10.1016/0022-2836(88)90247-1
Source DB: PubMed Journal: J Mol Biol ISSN： 0022-2836 Impact factor: 5.469