| Literature DB >> 2264837 |
Abstract
Two distinct lattice structures are observed for two-dimensional (2-D) antibody organization on phospholipid films. A low-order, small-unit-cell, square lattice is obtained at pH 7 and below for mouse IgE, mouse IgG2a and IgG2b and rabbit IgG. At pH 7.5 and above, the observed lattice structure switches to a large-unit-cell, hexagonal type for rabbit IgG and mouse IgE. Interchain disulphide reduction by exposure to 2 mM-dithiothreitol results in the formation of the compact 2-D lattice for all cases and for all pH conditions.Entities:
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Year: 1990 PMID： 2264837 PMCID： PMC1149654 DOI： 10.1042/bj2720045
Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857