Jawad H Butt1, Lauge Østergaard1, Thomas A Gerds2,3, Marie D Lauridsen1, Kristian Kragholm4, Morten Schou5, Matthew Phelps2, Gunnar H Gislason2,5, Christian Torp-Pedersen6, Lars Køber1, Emil L Fosbøl1. 1. Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark. 2. The Danish Heart Foundation, Copenhagen, Denmark. 3. Department of Biostatistics, University of Copenhagen, Copenhagen, Denmark. 4. Department of Cardiology, North Denmark Regional Hospital, Aalborg University Hospital, Aalborg, Denmark. 5. Department of Cardiology, Herlev-Gentofte University Hospital, Copenhagen, Denmark. 6. Department of Clinical Research and Cardiology, Nordsjællands Hospital, Hillerød, Denmark.
Abstract
AIMS: To investigate the admission rates of cardiovascular diseases, overall and according to subgroups, and subsequent mortality rates during the coronavirus disease 2019 societal lockdown (12 March 2020) and reopening phase (15 April 2020) in Denmark. METHODS AND RESULTS: Using Danish nationwide registries, we identified patients with a first-time acute cardiovascular admission in two periods: (i) 2 January-16 October 2019 and (ii) 2 January-15 October 2020. Weekly incidence rates of a first-time cardiovascular admission, overall and according to subtypes, in the two periods were calculated. The incidence rate of first-time cardiovascular admissions overall was significantly lower during the first weeks of lockdown in 2020 compared with a similar period in 2019 but increased after the gradual reopening of the Danish society. A similar trend was observed for all subgroups of cardiovascular diseases. The mortality rate among patients admitted after March 12 was not significantly different in 2020 compared with 2019 [mortality rate ratio 0.98; 95% confidence interval (CI) 0.91-1.06)]. CONCLUSION: In Denmark, we observed a substantial decrease in the rate of acute cardiovascular admissions, overall and according to subtypes, during the first weeks of lockdown. However, after the gradual reopening of the Danish society, the admission rates for acute cardiovascular diseases increased and returned to rates similar to those observed in 2019. The mortality rate in patients admitted with cardiovascular diseases during lockdown was similar to that of patients during the same period in 2019. Published on behalf of the European Society of Cardiology. All rights reserved.
AIMS: To investigate the admission rates of cardiovascular diseases, overall and according to subgroups, and subsequent mortality rates during the coronavirus disease 2019 societal lockdown (12 March 2020) and reopening phase (15 April 2020) in Denmark. METHODS AND RESULTS: Using Danish nationwide registries, we identified patients with a first-time acute cardiovascular admission in two periods: (i) 2 January-16 October 2019 and (ii) 2 January-15 October 2020. Weekly incidence rates of a first-time cardiovascular admission, overall and according to subtypes, in the two periods were calculated. The incidence rate of first-time cardiovascular admissions overall was significantly lower during the first weeks of lockdown in 2020 compared with a similar period in 2019 but increased after the gradual reopening of the Danish society. A similar trend was observed for all subgroups of cardiovascular diseases. The mortality rate among patients admitted after March 12 was not significantly different in 2020 compared with 2019 [mortality rate ratio 0.98; 95% confidence interval (CI) 0.91-1.06)]. CONCLUSION: In Denmark, we observed a substantial decrease in the rate of acute cardiovascular admissions, overall and according to subtypes, during the first weeks of lockdown. However, after the gradual reopening of the Danish society, the admission rates for acute cardiovascular diseases increased and returned to rates similar to those observed in 2019. The mortality rate in patients admitted with cardiovascular diseases during lockdown was similar to that of patients during the same period in 2019. Published on behalf of the European Society of Cardiology. All rights reserved.
Authors: Vess Stamenova; Cherry Chu; Andrea Pang; Jiming Fang; Ahmad Shakeri; Peter Cram; Onil Bhattacharyya; R Sacha Bhatia; Mina Tadrous Journal: PLoS One Date: 2022-04-25 Impact factor: 3.752
Authors: Daniel Mølager Christensen; Jawad Haider Butt; Emil Fosbøl; Lars Køber; Christian Torp-Pedersen; Gunnar Gislason; Matthew Phelps Journal: Am Heart J Date: 2021-07-15 Impact factor: 4.749