Literature DB >> 3372359

LL-F28249 antibiotic complex: a new family of antiparasitic macrocyclic lactones. Isolation, characterization and structures of LL-F28249 alpha, beta, gamma, lambda.

G T Carter1, J A Nietsche, M R Hertz, D R Williams, M M Siegel, G O Morton, J C James, D B Borders.   

Abstract

A new family of antiparasitic macrolides has been isolated from Streptomyces cyaneogriseus sp. noncyanogenus. The compounds, designated LL-F28249 alpha, beta, gamma and lambda, possess potent antiparasitic activity. The isolation, purification and structure determination by spectroscopic methods are presented.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3372359     DOI： 10.7164/antibiotics.41.519

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  9 in total

Review 1.  Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters.

Authors:  Haruo Ikeda; Shin-ya Kazuo; Satoshi Omura
Journal:  J Ind Microbiol Biotechnol       Date:  2013-08-29       Impact factor: 3.346

2.  Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolites.

Authors:  Mamoru Komatsu; Kyoko Komatsu; Hanae Koiwai; Yuuki Yamada; Ikuko Kozone; Miho Izumikawa; Junko Hashimoto; Motoki Takagi; Satoshi Omura; Kazuo Shin-ya; David E Cane; Haruo Ikeda
Journal:  ACS Synth Biol       Date:  2013-01-17       Impact factor: 5.110

3.  Two new α-class milbemycin metabolites from mutant Streptomyces avermitilis NEAU1069-3.

Authors:  Lian-jie Li; Dan Zhou; An-liang Chen; Jun Huang; Hui Zhang; Ji-dong Wang; Wen-sheng Xiang
Journal:  J Antibiot (Tokyo)       Date:  2014-11-26       Impact factor: 2.649

4.  Urban park soil microbiomes are a rich reservoir of natural product biosynthetic diversity.

Authors:  Zachary Charlop-Powers; Clara C Pregitzer; Christophe Lemetre; Melinda A Ternei; Jeffrey Maniko; Bradley M Hover; Paula Y Calle; Krista L McGuire; Jeanne Garbarino; Helen M Forgione; Sarah Charlop-Powers; Sean F Brady
Journal:  Proc Natl Acad Sci U S A       Date:  2016-11-28       Impact factor: 11.205

5.  Development of a mechanism of action-based screen for anthelmintic microbial metabolites with avermectinlike activity and isolation of milbemycin-producing Streptomyces strains.

Authors:  C L Haber; C L Heckaman; G P Li; D P Thompson; H A Whaley; V H Wiley
Journal:  Antimicrob Agents Chemother       Date:  1991-09       Impact factor: 5.191

Review 6.  Heartworm disease - Overview, intervention, and industry perspective.

Authors:  Sandra Noack; John Harrington; Douglas S Carithers; Ronald Kaminsky; Paul M Selzer
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2021-04-27       Impact factor: 4.077

7.  Evaluation of Bacillus cereus and Bacillus pumilus metabolites for anthelmintic activity.

Authors:  M L Vijaya Kumar; B Thippeswamy; I L Kuppust; K J Naveenkumar; C K Shivakumar
Journal:  Pharmacognosy Res       Date:  2015 Jan-Mar

Review 8.  Perspectives on the utility of moxidectin for the control of parasitic nematodes in the face of developing anthelmintic resistance.

Authors:  Roger K Prichard; Timothy G Geary
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2019-06-15       Impact factor: 4.077

Review 9.  The equine ascarids: resuscitating historic model organisms for modern purposes.

Authors:  Jennifer L Cain; Martin K Nielsen
Journal:  Parasitol Res       Date:  2022-08-20       Impact factor: 2.383
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.